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Could a keto diet help treat bipolar depression?

Could a keto diet help treat bipolar depression?

Author: BBC Radio 4 June 9, 2026 Duration: 28:23
All in the Mind
HealthHealth & FitnessFitnessScience

Claudia Hammond explores intriguing early evidence that a ketogenic diet - high fat, low carbs - might help treat bipolar depression.

We already know this diet can help with some kinds of epilepsy. But now, after a promising pilot study, the Wellcome trust is funding a £7.9 million trial to look at whether it could also help reduce depression in people living with bipolar disorder. Professor Daniel Smith and research fellow Dr Iain Campbell from the University of Edinburgh, take us into the emerging field of ‘metabolic psychiatry’.

Also in the programme, Professor Nilli Lavie of UCL reveals what happens to our brain’s grey matter as we try to stay focused in an age of constant distraction. As information and entertainment are always within reach, her research asks how these shifting habits may be reshaping our attention - and our brains.

And Professor Daryl O’Connor discusses emerging research into the hormone oxytocin and its surprising role in wound healing, as well as new insights into how cultural experiences might help slow the ageing process.

Presenter: Claudia Hammond Producer: Pamela Rutherford Studio Manager: Tim Heffer Production Coordinator: Jana Bennett-Holesworth Content Editor: Ilan Goodman


Ever wondered why we do the things we do, or how our thoughts truly shape our reality? All in the Mind, from BBC Radio 4, moves beyond simple self-help to explore the intricate workings of the human psyche. Guided by Claudia Hammond, each episode is a thoughtful journey into the latest research and evidence from the worlds of psychology, neuroscience, and mental health. You'll hear from leading scientists, clinicians, and sometimes people with direct personal experience, all contributing to a deeper understanding of topics like memory, emotion, resilience, and perception. This isn't just a theoretical discussion; it's about connecting scientific discovery to the everyday experiences that define us. The conversations in this podcast are designed to be accessible yet deeply informative, stripping away jargon to reveal what the evidence really tells us about our minds. Whether it's unpacking the mechanics of anxiety, the science of happiness, or the mysteries of consciousness, Claudia's nuanced approach provides clarity and insight. Tune in for a compelling blend of personal stories and rigorous science that challenges assumptions and illuminates the hidden forces behind our behaviour. This is a space for curious listeners who want to look beneath the surface of thought and feeling, discovering the fascinating evidence that explains how we all operate.
Author: Language: English Episodes: 50

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All in the Mind
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