In THE HEADACHE: The Science of a Most Confounding Affliction-and a Search for Relief (Mariner Books; on sale 7/15/2025), veteran science journalist Tom Zeller Jr. delivers a deeply reported journey into the world of headaches-equal parts gripping memoir, cutting-edge science, and insightful exploration of what it means to live with severe, unexplained, and recurrent head pain.For decades, Zeller has battled excruciating cluster headaches, a disorder so painful it is sometimes described as "suicide headache" in the scientific literature. But instead of succumbing to despair, he used his unique skills as a journalist to dig deeper. THE HEADACHE chronicles his personal quest for answers-from experimental drug trials to groundbreaking research on brain function, and even the unexpected possibilities of psychedelic therapy. Zeller's captivating narrative explores the history of headache treatment, the science behind the nervous system, and how modern medicine is finally starting to take these conditions seriously

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