Therapy for Stage IV NSCLC Without Driver Alterations: ASCO Living Guideline Update 2026.3.1 Part 1

Therapy for Stage IV NSCLC Without Driver Alterations: ASCO Living Guideline Update 2026.3.1 Part 1

Author: American Society of Clinical Oncology (ASCO) May 26, 2026 Duration: 13:27

Dr. Lyudmila Bazhenova joins the podcast to share the update to the living guideline on stage IV NSCLC without driver alterations. Dr. Bazhenova discusses the evidence reviewed for both non-squamous NSCLC, including the POD1IM-304 and BAP BRAIN trials, and squamous cell NSCLC, including the HARMONi-6 trial. She shares how these results impacted the clinical practice guideline, what they mean for patients receiving immunotherapy and chemotherapy, and where the panel is waiting for additional evidence to clarify the role of therapeutic options. Dr. Bazhenova encourages listeners to stay tuned for future updates to the living guideline after publication of data from the 2026 ASCO Annual Meeting.

Read the full living guideline "Therapy for Stage IV Non-Small Cell Lung Cancer without Driver Alterations, ASCO Living Guideline Version 2026.3.1"

LINK TO FULL TRANSCRIPT


The ASCO Guidelines podcast, from the American Society of Clinical Oncology, serves as an authoritative audio companion for oncology professionals. Each episode delves into the rationale and practical application of the society's latest evidence-based clinical practice guidance. You'll hear directly from the experts who helped develop these critical recommendations, gaining a deeper understanding of the data and discussions that shape contemporary cancer care. This podcast provides a vital channel for staying current in a rapidly advancing field, translating complex guidelines into actionable knowledge for clinical practice. It’s an essential resource for anyone dedicated to implementing the highest standards in oncology, offering clarity and context that goes beyond the published document. Tune in for a focused exploration of how new research directly informs treatment pathways and patient management strategies.
Author: Language: en-us Episodes: 50

ASCO Guidelines
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