405: 405 Winchester-Roosevelt's Medicine Gun For Lions

405: 405 Winchester-Roosevelt's Medicine Gun For Lions

Author: John McAdams January 8, 2026 Duration: 47:13

We're talking about the 405 Winchester today, which is President Theodore Roosevelt's legendary medicine gun for lions. To this day, that statement remains one of the most effective presidential endorsements of any product ever. We will discuss more details of how that cartridge performed for Theodore Roosevelt in Africa, plus I'll also cover the history and performance specs of the cartridge, it's strengths and limitations, some other hunting stories involving it, and some recommendations on the best use cases for the round. 

Sponsor: Get in touch with me to make your Africa hunting dreams come true on a hunt in South Africa. We offer outstanding hunting safaris, simplified hunt logistics, assistance with many of the pain points associated with a hunt, and up front pricing with no extra fees. We just opened bookings for 2027 and still have a few spots remaining for May, October, and November 2026. Visit bestsafarihunt.com or email me at john@thebiggamehuntingblog.com to learn more. Make sure to state that you're a podcast listener and I'll give you a special bonus!

North Fork produces several projectiles that are outstanding choices for the 405 Winchester that take the performance of the cartridge to the next level. You can purchase North Fork bullets in the .411 and .413 bore diameters (as well as many others: .308, .338, .375 caliber, etc.) directly from the North Fork web site, from MidwayUSA, or from our network of other distributors all over the world.

Please hit that "SUBSCRIBE" or "FOLLOW" button in your podcast app to receive future episodes automatically!


John McAdams hosts the Big Game Hunting Podcast, a conversation grounded in the realities of pursuing game across continents. Each episode feels like a detailed campfire talk, moving from the technical specifics of terminal ballistics and caliber selection to the raw, unforgettable narratives from the field in Africa, North America, and beyond. McAdams brings together a global community, with voices ranging from seasoned industry professionals to fellow hunters who call in with their own experiences. The focus is always on practical knowledge and authentic stories, stripping away any pretense to get to the heart of what hunters actually want to discuss. By sharing his own journey of learning and improvement, McAdams creates a space where curiosity and respect for the wilderness drive the dialogue. Tuning into this podcast means joining a serious yet accessible exchange where the complexities of the hunt are explored without filter. New conversations are released every Thursday, offering a consistent dose of insight and camaraderie for anyone passionate about the pursuit.
Author: Language: English Episodes: 100

Big Game Hunting Podcast - Hunting Africa, North America, & More!
Podcast Episodes
419: 257 Weatherby RPM With Richard Mann [not-audio_url] [/not-audio_url]

Duration: 52:50
Field & Stream shooting editor and 25 caliber aficionado Richard Mann joins me in this podcast episode to discuss the new, SAAMI standardized 257 Weatherby Rebated Precision Magnum. Richard discusses the origins of the 2…
417: Double Rifles, 500 NE & Elephant Charges With Jeff Rann [not-audio_url] [/not-audio_url]

Duration: 1:06:26
Jeff Rann, one of Africa's most legendary professional hunters with nearly 50 years guiding dangerous game, joins me on the podcast to share his incredible stories of hunting elephant in Botswana. He takes us inside what…
416: 416 Caliber Cartridges With Terry Wieland [not-audio_url] [/not-audio_url]

Duration: 1:46:24
Gunwriter Terry Wieland joins me on the show as we discuss his thoughts on the various .416 caliber cartridges: the 416 Rigby, the 416 Remington Magnum the 416 Weatherby Magnum, the 416 Ruger, and even the 416 Hoffman an…
415: 10 Best African Safari Book Recommendations For Hunters [not-audio_url] [/not-audio_url]

Duration: 23:24
Today, I'm unveiling my definitive list of what I think are the 10 greatest African hunting books ever written. This list of African safari book recommendations includes works from people like Hemingway, Roosevelt, Ruark…
414: Leopard Mauling To Sudan Bongo Hunts with Robin Hurt [not-audio_url] [/not-audio_url]

Duration: 1:03:14
Legendary Professional Hunter Robin Hurt joins me on the show today as we discuss some of his adventures hunting all over Africa like Kenya, Tanzania, Uganda, Sudan, Zaire, Zambia, and Namibia. As you can imagine from a…
412: Stories From The African Bushveld With Johan Seyffert [not-audio_url] [/not-audio_url]

Duration: 38:35
I sat down with Johan Seyffert, one of my South African Professional Hunters, at the 2026 Safari Club International convention and recorded a short interview about some of his more memorable hunts from 2025, some funny a…
411: 458 Win Mag vs 45-70 Govt Cartridge Comparison [not-audio_url] [/not-audio_url]

Duration: 1:28:59
Here's how the mighty 458 Winchester Magnum stacks up against the venerable 45-70 Government cartridge, especially with regards to how both perform in Africa. In this episode, we discuss the history, design characteristi…