Charles Guillemet, Ledger CTO — AI Agents, Self-Custody & Wallet Security

Charles Guillemet, Ledger CTO — AI Agents, Self-Custody & Wallet Security

Author: Bitcoin.com July 18, 2026 Duration: 23:34

🎙️ As AI agents become more capable, who should control your crypto wallet—you or the AI?

Charles Guillemet, CTO of Ledger, joins Alex Richardson at Proof of Talk 2026 to discuss the future of crypto security and why self-custody will become even more important in the age of AI.

Guillemet shares how he got started in hardware security, why Ledger built its underground Dungeon security lab, and how the company stress-tests wallets, chips, and software before attackers can exploit them.

The conversation also explores why AI agents should never have direct access to private keys, how Ledger is approaching AI-powered wallets, and the security challenges posed by quantum computing, side-channel attacks, and the next generation of digital assets.

Topics include:

  • Ledger's Dungeon security lab
  • Hardware wallet security
  • AI agents and wallet safety
  • Self-custody and private key protection
  • Clear signing
  • Quantum and side-channel attacks
  • The future of secure wallet design

🎧 Be sure to subscribe on your favorite podcatcher for more conversations with the leaders, builders, and innovators shaping the future of Bitcoin, crypto, and digital finance.

Join our community and follow us for the latest updates ⬇️

► YouTube: https://www.youtube.com/@BitcoincomNews
► X (Bitcoin.com): https://x.com/Bitcoincom
► X (Bitcoin.com News): https://x.com/bitcoinnews
► OrangeRock on X: https://x.com/orangerockxyz
► Telegram: https://t.me/www_Bitcoin_com
► Discord: https://discord.gg/9NGNJEnwmW
► LinkedIn (Bitcoin.com): https://www.linkedin.com/company/bitcoin.com/
► LinkedIn (Bitcoin.com News): https://www.linkedin.com/company/bitcoin-com-news/


Bitcoin.com News Interviews offers a direct line to the people shaping the digital economy. Each episode features a focused conversation, pulling back the curtain on the strategies, challenges, and personal insights of influential figures from across the Bitcoin and broader cryptocurrency landscape. You'll hear founders explaining the real-world problems their projects aim to solve, investors discussing the shifting tides of market sentiment, and veteran leaders reflecting on the industry's rapid evolution. This isn't about hype or price predictions; it's about understanding the foundational ideas and human decisions driving this technological frontier. The discussions are grounded and substantive, providing context that goes far beyond headlines. By listening to this podcast, you gain access to the nuanced perspectives that often remain behind the scenes, offering a clearer picture of where things have been and where they might be headed. It's a resource for anyone looking to move past surface-level news and engage with the substantive dialogue happening within the cryptoverse. These interviews serve as an essential audio companion, translating complex concepts into relatable conversations and connecting the dots between technological innovation, economic shifts, and community building. Tune in for thoughtful, long-form dialogues that illuminate the key players and pivotal moments defining this dynamic space.
Author: Language: en-us Episodes: 50

Bitcoin.com News Interviews
Podcast Episodes
Stablecoins Could Become the Default Money by 2030 | Reeve Collins [not-audio_url] [/not-audio_url]

Duration: 28:47
Could stablecoins become the default way we hold and move money by 2030?WeFi Chairman Reeve Collins Reeve Collins joins Alex Richardson to discuss what could drive the next phase of stablecoin adoption and why banks may…
The CLARITY Act Failed in the Senate. What Comes Next for Crypto? [not-audio_url] [/not-audio_url]

Duration: 35:57
The CLARITY Act failed to advance in the U.S. Senate leaving one of crypto’s biggest regulatory questions unresolved.So what happens now for DeFi, crypto companies, developers, and users in the United States?Orest Gavryl…
Why Bitcoin Miners Are Becoming AI and Energy Companies [not-audio_url] [/not-audio_url]

Duration: 23:04
Bitcoin mining is no longer just about mining machines and hash rate. It is increasingly becoming a story about energy, infrastructure, AI, and compute.Gwyn Lauber, Vice President of Corporate Affairs at Canaan, joins Da…
Inside the Rise of Crypto Wrench Attacks [not-audio_url] [/not-audio_url]

Duration: 1:09:10
Crypto security isn’t just about protecting wallets from hackers. Increasingly, the person holding the crypto can become the target.In this episode, David Sencil sits down with Dr. Marilyne Ordekian Panossian, incoming A…
Bitcoin Miners Are Pivoting to AI. What Happens to Bitcoin Mining? [not-audio_url] [/not-audio_url]

Duration: 19:19
Bitcoin miners are increasingly turning toward AI and data centers, but that shift could create new opportunities for the miners who stay focused on Bitcoin.In this episode, David Sencil sits down with Karun Mackencherry…
Digital Sovereignty and the Global Race for Stablecoin Regulation [not-audio_url] [/not-audio_url]

Duration: 58:21
The Digital Sovereignty Alliance (DSA) is a nonprofit social welfare organization committed to advocating for public policies that support ethical innovation in decentralized technologies, blockchain, cryptocurrency, Web…
Why Korea Blockchain Week 2026 Is Betting Big on Institutions [not-audio_url] [/not-audio_url]

Duration: 39:02
FactBlock CEO Andrew Park joins David Sencil to discuss how Korea Blockchain Week has evolved and why KBW 2026 is leaning further into institutions, policy, real-world assets, stablecoins, tokenized equities, and B2B dea…
Crypto’s $70B vs. $8B Divide: Where Is the Value Really Going? [not-audio_url] [/not-audio_url]

Duration: 51:29
Who is actually capturing the value being created in crypto?In this episode, David Sencil sits down with Lorenzo Valente, Director of Research for Digital Assets at ARK Invest, to unpack a striking gap: centralized crypt…