Two-Time Survivor: Cheyenne Heflin on Losing a Leg, a Lung, and Never Losing Humor.

Two-Time Survivor: Cheyenne Heflin on Losing a Leg, a Lung, and Never Losing Humor.

Author: Dr. Brad Miller July 3, 2026 Duration: 1:08:12

On this episode of the Cancer and Comedy Podcast, Dr. Brad Miller and Cheyenne Heflin open up about a topic that rarely makes it into the discharge summary—but lives in the classroom, the family room, and the therapist’s chair:

What happens to your identity, your mental health, and your sense of “who I am” when cancer takes your leg at 13…and then comes back for your lung just as you’re about to become a counselor?

Speaking from her own story—first as a middle‑schooler with osteosarcoma and an above‑knee amputation, then as a grad student blindsided by a lung recurrence—Cheyenne has a candid, funny, and deeply compassionate conversation with Brad about living in a changed body, using humor as both lifeline and mask, and learning to become more than “the cancer kid.”

In this honest, tender, and laugh‑out‑loud real conversation, Brad and Cheyenne share:

  • Going from knee pain to a childhood bone cancer diagnosis and chemo in a matter of weeks
  • Losing her leg above the knee and starting high school bald, disabled, and in a new city where she knew no one
  • Leaning hard into humor—cracking jokes about her missing leg so other people wouldn’t feel awkward
  • Using her prosthetic leg as a prop: hiding by the choir room door and swinging it at classmates (and her choir teacher) to “guard” the room
  • Becoming “the funny one” in choir and activities, melting tension when rehearsal stress was sky‑high
  • Realizing in college and during COVID that humor wasn’t just coping—it was hiding the depth of her pain
  • Losing a close friend who saw through the jokes, insisted “you are not fine,” and stepped away when Cheyenne refused to face what she was feeling
  • Hitting a breaking point in COVID—moving back home, clashing with her sisters, explosive arguments with her dad, and finally snapping under the weight of it all
  • Sitting on the porch while her dad, scared for her, says, “We need to get you real help,” and pushing her to consider antidepressants
  • Wrestling with fear that taking meds meant she’d end up like her mom, who also struggled with mental illness—and then discovering medication actually made therapy skills usable
  • Letting go of med‑school dreams, admitting she struggled with heavy science, and pivoting toward psychology and counseling
  • Getting all the way to her counseling internship in a pediatric practice—only to have a persistent cough lead to scans that read “highly suspicious for recurrent cancer”
  • Facing a massive lung tumor, chemo that didn’t shrink it, and a total removal of her right lung—and what day‑to‑day life is really like with only one lung

They also talk about:

  • Choosing to show up to chemo in ridiculous hats—frogs, buckets, propellers—and inviting family, friends, and coworkers to join the bit so they could bring light instead of pity
  • How her internship coworkers even sent a funny hat in a care package, giving them a way to participate in her healing
  • The huge mental‑health gap in pediatric cancer care: being checked only to see if she was suicidal, then left to navigate school, disability, and trauma mostly on her own
  • Why she’s determined to close that gap as a therapist and speaker, using her story to advocate for psychosocial care alongside medical treatment
  • Working with a young patient diagnosed with OCD, using exposure therapy grounded in trust and warmth, and watching that child’s symptoms disappear
  • The powerful moment when that family told her how much better life was—and Cheyenne finally believed, “I really can help people.”

This episode isn’t a how‑to manual for “perfect resilience after cancer.” It’s a real‑world guide to:

  • Talking about the hard stuff instead of hiding behind “I’m fine” and a joke
  • Using humor as a tool for light, not a mask that keeps you from feeling
  • Redefining yourself when your body has been cut, stitched, rearranged—and labeled “survivor” before you’re ready

If cancer has changed your body, your plans, or the way you see yourself in the mirror, this conversation will help you:

  • Feel less alone in the awkward, unspoken mix of laughter, grief, and growth
  • Start the conversations you’ve been avoiding—about mental health, medication, and who you are beyond your diagnosis
  • Find hope, humor, and new ways to see yourself as more than what happened to you in a “new normal” you never chose

Together, we can keep turning the grim realities of cancer into the grin of a life still full of purpose, connection, and laughter that tells the truth.


There's a particular kind of alchemy that happens when serious things meet sincere laughter, and that's the space where you'll find Cancer and Comedy: Helping Cancer Impacted People to Cope with Hope and Humor. Hosted by Dr. Brad Miller, this podcast emerged from a deeply personal place. Fresh into retirement after 43 years as a pastor, Brad received a prostate cancer diagnosis during the Christmas season of 2022. His instinctive reaction-to laugh as a way to keep from crying-sparked a mission. Each episode is built on the belief that those touched by cancer are not done living, and that facing the grim with a grin is a powerful form of resilience. You'll hear conversations that blend candid stories from the cancer journey with a genuine, often surprising, sense of humor. It’s not about dismissing the difficulty, but about discovering pockets of light and levity within it. Brad brings his unique perspective as both a longtime spiritual guide and a current patient, creating dialogues that are as educational about mental and physical wellness as they are uplifting. This isn't a lecture; it's a companionable audio experience for anyone seeking to fortify their spirit with hope and an honest, sometimes healing, laugh. Tune in for a podcast that redefines strength, proving that coping can be a creative, and even comedic, act of self-improvement.
Author: Language: English Episodes: 50

Cancer and Comedy: Helping Cancer Impacted People to Cope with Hope and Humor
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