Cracking the Cardiac Code

Cracking the Cardiac Code

Author: Children's Hospital Colorado May 6, 2025 Duration: 30:56

The heart is an involved organ in many syndromes impacting kids. Our understanding of the genetic underpinnings of pediatric heart conditions has improved greatly with better access to genetic testing. From inherited arrythmias to structural congenital heart defects, genetic testing is becoming an essential part of the diagnosis, treatment and family counseling in kids with heart problems.

To help us understand this evolving field, we are joined by Kathryn Chatfield, MD. She is the director of the Cardiac Genetics and Aortopathy Program at Children's Hospital Colorado and specializes in clinical genetics and genomics, as well as cardiology. She is also an Associate Professor of Pediatric Cardiology at the University of Colorado School of Medicine.

Some highlights from this episode include: 

  • How to determine which kids should undergo a cardiac genetics workup and which ones may not need it 
  • Understanding if these diseases are inherited, spontaneous or mutations 
  • Why some kids with heart conditions are not seen until they are older 
  • How primary care providers can interact with specialized genetics clinics 

 For more information on Children's Colorado, visit: childrenscolorado.org. 


For those dedicated to the health of children, Charting Pediatrics serves as a vital, ongoing conversation directly from the front lines of pediatric care. Produced by the multidisciplinary experts at Children's Hospital Colorado, this weekly podcast delves into the nuanced realities of modern medicine for young patients. Each episode moves beyond textbook summaries to explore the practical application of groundbreaking research, emerging innovations, and essential educational resources. The discussions are candid, often tackling the complex challenges that clinicians face daily, from evolving treatment protocols to systemic issues within the healthcare community. Now in its eighth season, the program has established itself as a trusted source for physicians, nurses, and allied health professionals seeking to deepen their knowledge and refine their practice. Listening to this podcast feels like gaining direct access to a roundtable of specialists, all focused on a single goal: empowering medical providers with the context and confidence needed to make the best decisions for their patients. The tone is collegial and insightful, transforming the latest evidence and clinical experience into actionable understanding. It’s where the science of pediatrics meets the art of its application, fostering a supportive dialogue for anyone committed to advancing child health.
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