The Science Behind Autism and Medications

The Science Behind Autism and Medications

Author: Children's Hospital Colorado November 20, 2025 Duration: 35:38

Recently, leucovorin and acetaminophen have been at the center of new discussions in pediatric medicine. Could leucovorin really help some children with autism? Does the latest evidence suggest acetaminophen has any impact on neurodevelopment? In today's episode, we'll break down what the science actually tells us, what remains uncertain and how pediatricians can confidently guide families through these complex topics.

Joining us for this important discussion is Abigail Angulo, MD. She is a developmental-behavioral pediatrician at Children's Hospital Colorado. She is also an associate professor at the University of Colorado School of Medicine.

Some highlights from this episode include: 

  • The science behind autism 
  • The role of Tylenol in pregnancy and newborn development 
  • What leucovorin is used for and when it should be prescribed 
  • How to navigate difficult conversations with families who expect certain outcomes

For more information on Children's Colorado, visit: childrenscolorado.org. 


For those dedicated to the health of children, Charting Pediatrics serves as a vital, ongoing conversation directly from the front lines of pediatric care. Produced by the multidisciplinary experts at Children's Hospital Colorado, this weekly podcast delves into the nuanced realities of modern medicine for young patients. Each episode moves beyond textbook summaries to explore the practical application of groundbreaking research, emerging innovations, and essential educational resources. The discussions are candid, often tackling the complex challenges that clinicians face daily, from evolving treatment protocols to systemic issues within the healthcare community. Now in its eighth season, the program has established itself as a trusted source for physicians, nurses, and allied health professionals seeking to deepen their knowledge and refine their practice. Listening to this podcast feels like gaining direct access to a roundtable of specialists, all focused on a single goal: empowering medical providers with the context and confidence needed to make the best decisions for their patients. The tone is collegial and insightful, transforming the latest evidence and clinical experience into actionable understanding. It’s where the science of pediatrics meets the art of its application, fostering a supportive dialogue for anyone committed to advancing child health.
Author: Language: English Episodes: 100

Charting Pediatrics
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