Exploring the Link Between Niacin and Fatty Liver Disease

Exploring the Link Between Niacin and Fatty Liver Disease

Author: Dr. Mercola February 24, 2026 Duration: 14:19
  • Fatty liver disease is the most common liver disorder, driven by obesity, Type 2 diabetes, and insulin resistance. It often progresses silently for years before symptoms appear
  • Niacin helps your body use energy better. It turns down a molecule called microRNA-93, which normally blocks two key proteins that help your cells make energy and burn fat. By restoring those proteins, niacin helps your mitochondria work more efficiently. This shift supports fat burning in your liver instead of fat storage
  • Higher niacin intake has been linked to reduced liver fat, lower inflammation, improved insulin sensitivity, better cholesterol levels, and reduced long-term mortality in fatty liver patients
  • Niacinamide is the better choice compared to niacin because of its function as an NAD+ precursor. The ideal dosage is 50 milligrams three times a day, ideally in powder form for precise intake. Niacinamide also doesn't cause skin flushing
  • Increasing choline intake is the best way to manage fatty liver disease. Research shows it helps transport fat out of the liver. While there are several types of choline supplements available, citicoline is the preferred one because of its high bioavailability

Each week, Dr. Joseph Mercola-Take Control of Your Health offers a direct conversation about navigating the often-confusing world of wellness. Dr. Mercola brings decades of experience as a natural health advocate to these discussions, focusing on practical strategies that go beyond conventional approaches. The episodes dig into the interconnected areas of holistic health, physical fitness, and alternative methods for building resilience. You’ll hear detailed explorations of how everyday choices impact long-term vitality, with an emphasis on personal agency and evidence-informed alternatives. This isn’t about quick fixes but about understanding the underlying principles that can help you make better decisions for yourself and your family. The tone is straightforward and investigative, aiming to equip you with knowledge that is frequently overlooked. Tuning into this podcast feels like accessing a deep resource of non-mainstream health perspectives, all centered on the fundamental goal of sustainable well-being. It’s for anyone who feels that managing their health requires looking at the full picture, from nutrition and movement to the less obvious environmental factors. Dr. Mercola’s weekly insights serve as a catalyst for taking a more active, informed role in your own health journey.
Author: Language: English Episodes: 100

Dr. Joseph Mercola - Take Control of Your Health
Podcast Episodes
Mercury Fillings Raise Mercury Levels Throughout Your Body [not-audio_url] [/not-audio_url]

Duration: 6:49
Dental "silver fillings" are made with roughly 50% mercury, and researchers found adults with amalgam fillings carried significantly higher blood mercury levels than people without them The study showed that mercury expo…
Are You Taking Vitamin D at the Wrong Time? [not-audio_url] [/not-audio_url]

Duration: 6:42
Taking vitamin D at midday with your largest meal improves absorption and helps your body use it more effectively for mood, sleep, and brain function Normal vitamin D blood levels don't guarantee results because your bod…
Garden Therapy: Why Getting Your Hands Dirty Is the Best 'Medicine' [not-audio_url] [/not-audio_url]

Duration: 7:14
Gardening adds meaningful weekly physical activity without requiring a formal workout, helping you build strength, balance, and endurance through real-world movement Spending time in the garden lowers stress hormones and…
Can You Prevent the Hunched Back of Kyphosis? [not-audio_url] [/not-audio_url]

Duration: 6:16
A hunched back develops gradually as weak muscles, poor posture, and declining bone strength allow gravity to pull your spine forward over time Up to 40% of adults over 60 experience significant spinal curvature, and the…
Study Reveals Bile as Reservoir for Microplastics in Humans [not-audio_url] [/not-audio_url]

Duration: 6:02
Microplastics have been found in every human bile sample tested, showing that your body is likely actively storing them in a key digestive fluid Higher levels of microplastics are linked to gallstones, meaning everyday p…