Targeting Cellular Senescence for Healthier, More Youthful Skin With Dr. Alessandra Zonari

Targeting Cellular Senescence for Healthier, More Youthful Skin With Dr. Alessandra Zonari

Author: Dr. Kara Fitzgerald July 9, 2024 Duration: 58:11
*Save the date! Join me and Dr. Alessandra Zonari for a free webinar on July 25th 2024 and get your questions answered on all things OS-01 peptide and biological aging. Register at https://www.drkarafitzgerald.com/webinars/

I'm thrilled to be joined by Dr. Alessandra Zonari to take a deep dive into a breakthrough in skincare science that has caught my attention—OneSkin's OS-01 peptide. This episode explores how OS-01 targets cellular senescence, the core of aging, potentially transforming skin health - preserving function, not just aesthetics. I'm particularly impressed by OneSkin's commitment to rigorous research and evidence-based results. Their approach rejuvenates skin function in addition to enhancing its natural radiance, elasticity, and even its microbiome. This could be a significant advancement for individuals managing aging skin or conditions like atopic dermatitis.

Throughout our discussion, we explore the scientific foundation behind OS-01 and its clinical implications and uncover how this peptide may redefine skincare protocols, offering new possibilities for healthier, more radiant skin. Whether you're a practitioner seeking innovative solutions for patients for ultrasensitive skin or dermatitis, or someone passionate about maintaining skin health, this episode promises insights that could reshape your approach to skincare. And if you’re using OneSkin, I'd be curious to hear from you. You can post a comment wherever you're listening to this or email me directly at DrKaraFitzgerald.com. ~DrKF

Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources.

GUEST DETAILS

Alessandra Zonari, PhD

OneSkin co-founder and Chief Scientific Officer, Alessandra Zonari, PhD joined the early team in 2017 dedicating her time to understanding the underlying mechanism of the aging process and developing solutions to reverse skin’s biological age. Zonari is the co-inventor of five patents and has published more than 20 peer-reviewed papers in scientific journals.

Email: alessandra@oneskin.co

THANKS TO OUR SPONSOR

OneSkin: Website

PROMO

Try OneSkin for yourself with coupon code DRKARA15 to receive 15% off your first purchase at Website

SHOW NOTES

Animated science video explaining how OS-01 works Another Study Website

Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models Study Website

In vitro and in vivo toxicity assessment of the senotherapeutic Peptide 14 Study Website

Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging Another Study Website

MolClock: Estimate DNA methylation age of Skin Tissues Study Website

Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation Another Study Website

Senotherapeutics, Senolytics, and Senomorphics -- What are they and what is OS-01? Study Website


In each episode of Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics, host Dr. Kara Fitzgerald sits down with leading researchers and clinicians to explore the intricate science that is reshaping our approach to health. These conversations move beyond surface-level advice, digging into the mechanisms of epigenetics and the practical strategies for extending healthspan. You’ll hear detailed discussions on emerging research, with a focus on how our environment and choices influence genetic expression over a lifetime. This podcast is designed for anyone curious about the actionable science behind longevity, from healthcare practitioners seeking clinical insights to informed patients ready to engage deeply with their own wellness. The dialogue is grounded in functional medicine principles, translating complex studies into meaningful information that can be applied both in clinical settings and daily life. Dr. Fitzgerald guides these explorations with a clear and thoughtful perspective, ensuring each episode builds a comprehensive understanding of how modern science is personalizing the path to lasting health. Tune in for a nuanced and evidence-based journey to the forefront of medicine.
Author: Language: English Episodes: 100

Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics
Podcast Episodes
Seed Oils vs Science: What the Data Shows | Dr. Bill Harris [not-audio_url] [/not-audio_url]

Duration: 1:17:53
Fatty acids remain one of the most debated areas in clinical nutrition, yet many widely held beliefs may not align with current evidence. In this episode of New Frontiers in Functional Medicine, Dr. Kara Fitzgerald sits…
When High Protein Backfires in the Gut  Dr. Tom Fabian [not-audio_url] [/not-audio_url]

Duration: 1:00:02
In this episode of New Frontiers in Functional Medicine, Dr. Kara Fitzgerald speaks with Tom Fabian, PhD, Senior Educator and Research Specialist at Diagnostic Solutions Laboratory, about why higher protein intake doesn’…
Why Bone Loss Accelerates With Aging: The Gut–Bone Connectio [not-audio_url] [/not-audio_url]

Duration: 51:14
Bone loss doesn’t start when fractures happen — it begins years earlier. In this episode, we explore how bone aging accelerates during menopause and the emerging role of the gut microbiome as a driver of skeletal decline…
Epstein Files: A Functional Medicine Response [not-audio_url] [/not-audio_url]

Duration: 58:52
The continued release of the Epstein files has sparked difficult but necessary conversations across the medical, longevity, and wellness communities. In this candid and deeply reflective episode of New Frontiers in Funct…