Targeting Senescent Cells? Dose and Timing Matters - with Dr. Greg Kelly

Targeting Senescent Cells? Dose and Timing Matters - with Dr. Greg Kelly

Author: Dr. Kara Fitzgerald March 28, 2024 Duration: 1:16:16
Get ready for a deep dive into the world of cellular senescence and its implications for aging. Dr. Greg Kelly joins me on New Frontiers to explain the science behind targeting this Hallmark of Aging and share natural compounds and activities that target cellular senescence. I am particularly excited for you to hear his thoughts around dosing and cyclical timing of exposure to senolytic compounds, such as fisetin, luteolin, quercetin, and piperlongumine, and why that may make the difference between having the effect you want... or not. Don't miss his advice on smart exercise tweaks for aging and the caution that overdoing it with exercise in our later years is much more harmful than it was in our twenties. Lots to unpack here. Enjoy! - DrKF

In each episode of Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics, host Dr. Kara Fitzgerald sits down with leading researchers and clinicians to explore the intricate science that is reshaping our approach to health. These conversations move beyond surface-level advice, digging into the mechanisms of epigenetics and the practical strategies for extending healthspan. You’ll hear detailed discussions on emerging research, with a focus on how our environment and choices influence genetic expression over a lifetime. This podcast is designed for anyone curious about the actionable science behind longevity, from healthcare practitioners seeking clinical insights to informed patients ready to engage deeply with their own wellness. The dialogue is grounded in functional medicine principles, translating complex studies into meaningful information that can be applied both in clinical settings and daily life. Dr. Fitzgerald guides these explorations with a clear and thoughtful perspective, ensuring each episode builds a comprehensive understanding of how modern science is personalizing the path to lasting health. Tune in for a nuanced and evidence-based journey to the forefront of medicine.
Author: Language: English Episodes: 100

Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics
Podcast Episodes
Seed Oils vs Science: What the Data Shows | Dr. Bill Harris [not-audio_url] [/not-audio_url]

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Fatty acids remain one of the most debated areas in clinical nutrition, yet many widely held beliefs may not align with current evidence. In this episode of New Frontiers in Functional Medicine, Dr. Kara Fitzgerald sits…
When High Protein Backfires in the Gut  Dr. Tom Fabian [not-audio_url] [/not-audio_url]

Duration: 1:00:02
In this episode of New Frontiers in Functional Medicine, Dr. Kara Fitzgerald speaks with Tom Fabian, PhD, Senior Educator and Research Specialist at Diagnostic Solutions Laboratory, about why higher protein intake doesn’…
Why Bone Loss Accelerates With Aging: The Gut–Bone Connectio [not-audio_url] [/not-audio_url]

Duration: 51:14
Bone loss doesn’t start when fractures happen — it begins years earlier. In this episode, we explore how bone aging accelerates during menopause and the emerging role of the gut microbiome as a driver of skeletal decline…
Epstein Files: A Functional Medicine Response [not-audio_url] [/not-audio_url]

Duration: 58:52
The continued release of the Epstein files has sparked difficult but necessary conversations across the medical, longevity, and wellness communities. In this candid and deeply reflective episode of New Frontiers in Funct…