The Science-Backed Bitter Compound That Mimics GLP-1 (No Injections Needed!)

The Science-Backed Bitter Compound That Mimics GLP-1 (No Injections Needed!)

Author: Dr. Kara Fitzgerald August 5, 2025 Duration: 53:06
Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics
HealthHealth & FitnessFitness
I’ve been watching the science behind Calocurb evolve over the last year, and I have to say—this is one of the most exciting clinical tools I’ve seen emerge in the metabolic space in quite some time. A hops-derived compound that stimulates endogenous GLP-1, CCK, and PYY—without a prescription or injection? That’s a big deal, especially for patients struggling with appetite regulation, weight plateaus, or the aftermath of GLP-1 discontinuation.

In this episode, I sit down with Sarah Kennedy, founder of New Zealand-based Calocurb, to talk about the years of government-funded research that led to this discovery, the remarkable clinical outcomes they’ve seen so far, and how I’ve personally used it in my practice with excellent results. If you’re looking for science-backed, natural strategies to support appetite control, fasting, or GLP-1 transitions—this one’s worth a listen. ~DrKF

Check out the show notes at https://www.drkarafitzgerald.com/fxmed-podcast/ for the full list of links and resources.

GUEST DETAILS Sarah Kennedy, Founder and CEO of Calocurb Ltd.

Email: sarah.kennedy@calocurb.com LinkedIn: https://www.linkedin.com/in/sarah-kennedy-0a840b13/

Sarah Kennedy, BVSc, is a veterinarian and health industry leader with 20+ years in nutrition science and innovation. Now CEO of Calocurb, she brings a unique perspective on natural GLP-1 activation—bridging plant-based research, gut physiology, and clinical application.

THANKS TO OUR SPONSOR: Calocurb

EXCLUSIVE OFFER FOR NEW FRONTIERS LISTENERS

Manage cravings and feel full faster with Calocurb, a 100% natural capsule that supports healthy weight management. Visit http://calocurb.com/drkara10 and use code DRKARA10 at checkout.

CONNECT with DrKF

Join Dr. Kara Fitzgerald and leading experts *LIVE on Sept 17–19, 2025* for a free virtual Masterclass on redefining healthcare & longevity through the lens of science-backed, systems-based approach. Register now: https://www.functionalmedicineislongevitymedicine.com/

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DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb

Younger You book: https://tinyurl.com/mr4d9tym

Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw


In each episode of Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics, host Dr. Kara Fitzgerald sits down with leading researchers and clinicians to explore the intricate science that is reshaping our approach to health. These conversations move beyond surface-level advice, digging into the mechanisms of epigenetics and the practical strategies for extending healthspan. You’ll hear detailed discussions on emerging research, with a focus on how our environment and choices influence genetic expression over a lifetime. This podcast is designed for anyone curious about the actionable science behind longevity, from healthcare practitioners seeking clinical insights to informed patients ready to engage deeply with their own wellness. The dialogue is grounded in functional medicine principles, translating complex studies into meaningful information that can be applied both in clinical settings and daily life. Dr. Fitzgerald guides these explorations with a clear and thoughtful perspective, ensuring each episode builds a comprehensive understanding of how modern science is personalizing the path to lasting health. Tune in for a nuanced and evidence-based journey to the forefront of medicine.
Author: Language: English Episodes: 100

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Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics
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