The Tough Gut Playbook: Rebuilding Gut Resilience in IBS-Prone Patients

The Tough Gut Playbook: Rebuilding Gut Resilience in IBS-Prone Patients

Author: Dr. Kara Fitzgerald March 24, 2026 Duration: 55:49
Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics
HealthHealth & FitnessFitness
As more patients present with digestive sensitivity and increasingly restricted diets, restoring gut resilience has become a central clinical challenge. In this episode of New Frontiers in Functional Medicine, Dr. Kara Fitzgerald speaks with Colleen Cutcliffe, PhD, CEO and co-founder of Pendulum Therapeutics, about emerging microbiome science and practical strategies for supporting microbial balance, dietary tolerance, and metabolic health.

The discussion explores next-generation probiotic strains, fiber diversity, IBS patterns, and real-world approaches clinicians can use to help patients rebuild microbiome resilience and expand diet diversity in practice.

Full show notes + references: https://www.drkarafitzgerald.com/fxmed-podcast/

GUEST DETAILS

Colleen Cutcliffe, PhD, is CEO and Co-Founder of Pendulum Therapeutics, where she focuses on advancing microbiome science and metabolic health through next-generation probiotic research. She holds a PhD in Biochemistry and Molecular Biology from Johns Hopkins University and brings more than 25 years of experience across biotechnology, pharmaceuticals, and academic research.

THANKS TO OUR SPONSOR Pendulum Therapeutics - http://PendulumLife.com/Kara20 Email: hello@pendulumlife.com

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Using next-generation probiotics like live Akkermansia, Pendulum is designed to go beyond gut health to support metabolism. Visit http://PendulumLife.com/Kara20 and use code KARA20 for 20% off your first membership order. CONNECT with DrKF

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In each episode of Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics, host Dr. Kara Fitzgerald sits down with leading researchers and clinicians to explore the intricate science that is reshaping our approach to health. These conversations move beyond surface-level advice, digging into the mechanisms of epigenetics and the practical strategies for extending healthspan. You’ll hear detailed discussions on emerging research, with a focus on how our environment and choices influence genetic expression over a lifetime. This podcast is designed for anyone curious about the actionable science behind longevity, from healthcare practitioners seeking clinical insights to informed patients ready to engage deeply with their own wellness. The dialogue is grounded in functional medicine principles, translating complex studies into meaningful information that can be applied both in clinical settings and daily life. Dr. Fitzgerald guides these explorations with a clear and thoughtful perspective, ensuring each episode builds a comprehensive understanding of how modern science is personalizing the path to lasting health. Tune in for a nuanced and evidence-based journey to the forefront of medicine.
Author: Language: English Episodes: 100

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Dr. Kara Fitzgerald | New Frontiers in Functional Medicine, Longevity, Epigenetics
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