Cardiometabolic Disease, Fatty Liver & Weight Loss

Cardiometabolic Disease, Fatty Liver & Weight Loss

Author: Functional Forum April 24, 2024 Duration: 31:40

In this episode James Maskell is joined by returning guest, Dr. Shilpa Saxena, MD to continue exploring the use of GLP-1 agonists, specifically Semaglutide, for weight loss and cardiometabolic diseases.

The conversation reinforces the importance of using GLP-1s responsibly and in conjunction with lifestyle medicine coaching to address underlying behavioral issues and promote sustainable weight loss. Dr. Saxena emphasizes the need to address metabolic dysfunction comprehensively, considering factors such as fatty liver disease and insulin resistance, and using a combination of interventions, including herbs, botanicals, and lifestyle modifications.

They also discuss the potential side effects of GLP-1 agonists and strategies for minimizing them. Additionally, they touch on the role of group visits and community support in facilitating behavior change and long-term success in weight management.

Check out the full episode to hear their thoughts on:

  •        Normalizing discussions around weight without enabling poor health.
  •       The role of supportive communities to support behavior change
  •       Stigma around Semaglutide use
  •        Patient personas who functional medicine providers are best able to help, and those personas that are not a good fit for the functional medicine approach to weight loss.

Learn about Group Visit Toolkits


Hosted by the Functional Forum, Evolution of Medicine Podcast sits at the intersection of health, fitness, and alternative approaches to well-being. It’s a space for conversations that go beyond conventional treatment, exploring the ideas and practitioners actively reshaping how we think about care. Each episode features in-depth discussions with clinicians, researchers, and thought leaders who are redefining the patient journey. You’ll hear practical insights into functional medicine, preventative strategies, and the nuanced connections between lifestyle, nutrition, and long-term health. This podcast digs into the real-world application of these evolving principles, offering listeners a forward-looking perspective on what it means to truly support the body's innate capacity for healing. Tune in for a thoughtful exploration of the systems, science, and stories driving this shift, providing a valuable resource for both healthcare professionals and anyone invested in taking a more active role in their own wellness. The dialogue here is dedicated to understanding the full spectrum of what modern medicine can become.
Author: Language: English Episodes: 100

Evolution of Medicine Podcast
Podcast Episodes
Psychedelic Therapy [not-audio_url] [/not-audio_url]

Duration: 40:06
What does the future of psychiatry look like when psychedelics, functional medicine, and trauma therapy converge? In this episode of The Evolution of Medicine, James Maskell and Will Van Derveer, MD explore how psychedel…
A New Lever for Brain Health: Reversing Alzheimers 2.0 [not-audio_url] [/not-audio_url]

Duration: 32:30
What if cannabis could support brain health and cognitive function? In this episode of The Evolution of Medicine, James Maskell and Dr. Bonni Goldstein explore how medical cannabis interacts with the endocannabinoid syst…
Reversing Alzheimers 2.0 Summit Preview [not-audio_url] [/not-audio_url]

Duration: 34:59
What if cognitive decline and Alzheimer's could be reversed? In this episode of The Evolution of Medicine , James Maskell and Dr. Kristine Burke discuss the 2026 summit's advances in precision medicine and team-based app…
My Bevan Commission Presentation [not-audio_url] [/not-audio_url]

Duration: 31:51
In this solo episode, I'm diving into a concept that's been coming up again and again—in my work, in the data, and in conversations with practitioners around the world: network insufficiency. Put simply, when connections…
The Thyroid to IBS Journey [not-audio_url] [/not-audio_url]

Duration: 31:49
Host James Maskell interviews Dr. Izabella Wentz, a leader in thyroid health and functional medicine, about her new work on IBS (irritable bowel syndrome). The conversation explores how IBS is often misunderstood as a st…
The Pracititoner Burnout Trap [not-audio_url] [/not-audio_url]

Duration: 42:35
In this episode of The Evolution of Medicine, host James Maskell interviews Seth Conger, COO of Freedom Practice Coaching and long-time functional medicine practitioner and mentor. The conversation explores the structura…
Why Brain Health Is the Future of Longevity Medicine [not-audio_url] [/not-audio_url]

Duration: 34:23
In this episode of The Evolution of Medicine, host James Maskell interviews Dr. Ryan Arnold, founder of Clava Health and a former emergency and critical care physician who transitioned into functional medicine. The conve…
Betrayal and the Brain [not-audio_url] [/not-audio_url]

Duration: 34:15
In this episode of The Evolution of Medicine, host James Maskell interviews Debbie Silber, PhD, founder of the Post Betrayal Transformation Institute and author of Unstuck. The conversation explores why betrayal is a dis…
Your Best Shot: Holistic Approach to GLP-1 [not-audio_url] [/not-audio_url]

Duration: 36:12
In this episode of The Evolution of Medicine, host James Maskell interviews registered dietitian Ashley Koff about her new book Your Best Shot. The conversation explores the seismic impact of GLP-1 agonists like Ozempic…
From Artisan to Infrastructure [not-audio_url] [/not-audio_url]

Duration: 31:57
In this episode of The Evolution of Medicine, host James Maskell outlines a pivotal shift for functional medicine practitioners. He argues that the era of the "artisan" solo practitioner is ending—and that survival in 20…