Functional Forum Live from San Francisco

Functional Forum Live from San Francisco

Author: Functional Forum May 26, 2026 Duration: 35:39

What if chronic disease, cognitive decline, and even trauma were not fixed conditions—but modifiable biological states?

In this Functional Forum episode, James Maskell and Matt Wiggins bring together leading clinicians and researchers to explore the frontiers of precision and functional medicine.

They discuss SUPAR, a powerful biomarker for systemic inflammation that could reshape early disease detection. The conversation then turns to a groundbreaking cognitive decline trial showing major improvements in patients treated with functional medicine protocols compared to standard care.

The episode also explores the biology of loneliness and the "cell danger response," the reversibility of trauma through epigenetic mechanisms and psychedelic-assisted therapy, and emerging ideas about measuring masculinity as a clinical health indicator.

Together, these insights point toward a future where chronic disease may be detected earlier, treated systemically, and in some cases reversed.

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About the Guests:

This episode features multiple leading voices from the Functional Forum community, including clinicians and researchers in functional and precision medicine:

Matt Wiggins – Health innovator focused on bringing advanced biomarker testing, including SUPAR, into clinical practice

Dr. Kat Toups – Clinician involved in cognitive decline research using precision functional medicine approaches

Dr. Molly Maloof – Physician and educator specializing in metabolic health, loneliness biology, and cellular stress responses

Dr. David Rabin – Psychiatrist and neuroscientist studying trauma, epigenetics, and psychedelic-assisted therapy

Dr. Brad Jacobs – Clinician exploring novel frameworks for men's health and masculinity as a clinical metric

Dr. Ryan Adler – Advocate for integrating cognitive health protocols into mainstream clinical practice

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Social Handles:

Website: https://www.jamesmaskell.com/

X: https://x.com/mrjamesmaskell

Instagram: https://www.instagram.com/mrjamesmaskell

Facebook: https://www.facebook.com/jamesedwardmaskell/

Linkedin: https://www.linkedin.com/in/jamesmaskell

Youtube: https://www.youtube.com/FunctionalForum

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PODCAST

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Hosted by the Functional Forum, Evolution of Medicine Podcast sits at the intersection of health, fitness, and alternative approaches to well-being. It’s a space for conversations that go beyond conventional treatment, exploring the ideas and practitioners actively reshaping how we think about care. Each episode features in-depth discussions with clinicians, researchers, and thought leaders who are redefining the patient journey. You’ll hear practical insights into functional medicine, preventative strategies, and the nuanced connections between lifestyle, nutrition, and long-term health. This podcast digs into the real-world application of these evolving principles, offering listeners a forward-looking perspective on what it means to truly support the body's innate capacity for healing. Tune in for a thoughtful exploration of the systems, science, and stories driving this shift, providing a valuable resource for both healthcare professionals and anyone invested in taking a more active role in their own wellness. The dialogue here is dedicated to understanding the full spectrum of what modern medicine can become.
Author: Language: English Episodes: 100

Evolution of Medicine Podcast
Podcast Episodes
Cleveland Clinic Functional Medicine Update [not-audio_url] [/not-audio_url]

Duration: 26:24
Dr. James Carter, the director of the Center for Functional Medicine at Cleveland Clinic, discusses his journey to functional medicine and his role at Cleveland Clinic. Dr. Carter is also a vascular medicine specialist a…
Anthroposophic Medicine [not-audio_url] [/not-audio_url]

Duration: 39:26
In this episode, we learn about anthroposophic medicine from James Maskell's guest, Adam Blanning, MD. Anthroposophic medicine takes a holistic approach to humans, nature, illness, and healing by addressing the physical,…
Toxicity in Children: Protecting Future Generations [not-audio_url] [/not-audio_url]

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James Maskell's guest on this episode is Dr. Elisa Song, a holistic pediatrician whose mission is to educate clinicians and parents alike about environmental toxicity in children and how to help children thrive by improv…
Clearing Confusion Around Botanical Medicine with Dr. Guilliams [not-audio_url] [/not-audio_url]

Duration: 49:44
In this episode, Dr. Tom Guilliams rejoins the podcast to explore the complexities and misconceptions surrounding botanical medicine and how clinicians can maximize the therapeutic effects of herbs. We learn from Dr. Gui…
The Vagus Nerve: The Organ of Unity [not-audio_url] [/not-audio_url]

Duration: 46:17
In this podcast episode, James Maskell interviews Dr. Navaz Habib about the importance of the vagus nerve in healing and overall health. Dr. Habib explains that the vagus nerve plays a critical role in shifting the body…
Detox: What You Need To Know with Dr. Jeffrey Morrison [not-audio_url] [/not-audio_url]

Duration: 45:26
James Maskell's guest on this episode is Jeffrey Morrison, MD, whose clinical approach is to use nutrition to prevent or reverse degenerative and chronic disease. In both his clinical practice and as a member of the Boar…
Functional Optometry with Dr. Bryce Appelbaum [not-audio_url] [/not-audio_url]

Duration: 38:05
In this episode, James interviews Dr. Bryce Appelbaum, a neuro-optometrist. For the first time ever on the podcast, we learn about the field of functional optometry, including how it differs from traditional optometry. D…
Business of Functional Medicine: Live Life by Design [not-audio_url] [/not-audio_url]

Duration: 50:28
In this episode, Dr. Joan Rosenberg discusses her book, 90 Seconds to A Life You Love, and the concept of living life by design. Many believe their circumstances dictate their lives; our guest asserts that one can design…