Your Best Shot: Holistic Approach to GLP-1

Your Best Shot: Holistic Approach to GLP-1

Author: Functional Forum February 23, 2026 Duration: 36:12

In this episode of The Evolution of Medicine, host James Maskell interviews registered dietitian Ashley Koff about her new book Your Best Shot. The conversation explores the seismic impact of GLP-1 agonists like Ozempic and Wegovy—and how functional medicine can pivot from a "weight loss" mindset to a "weight health" approach.

Koff reframes these medications not as magic bullets, but as biosimilar hormone replacement tools that "switch on" receptor sites—without repairing the underlying ecosystem. She outlines a five-part Weight Health Hormone assessment and introduces a Physician–Dietitian–Health Coach triad to ensure sustainable outcomes.

The episode challenges practitioners to stay "agnostic about the agonist" and instead focus on metabolic repair, patient education, and structured team-based care.

 

About the Guest:

Ashley Koff, RD is a registered dietitian and functional nutrition expert focused on metabolic health, personalized nutrition, and hormone signaling. She is the author of Your Best Shot and advocates for a "Weight Health" approach that integrates assessment, repair, and team-based implementation.

 

Ashley Koff, RD

Website: https://thebetternutritionprogram.com/your-best-shot/#Order?utm_source=ig&utm_medium=social&utm_content=link_in_bio&fbclid=PAZXh0bgNhZW0CMTEAc3J0YwZhcHBfaWQMMjU2MjgxMDQwNTU4AAGn0Q9_BL_AVS4TE9ropSLtTkwP2y5sIOqKsbxZaaKPv3nNMm0Tq8QuWidcGUk_aem_U9Z5knW9eqsiMjw19fzflA 

Instagram: https://www.instagram.com/ashleykoffapproved/?hl=en

Facebook: https://www.facebook.com/ashleykoffapproved/

Linkedin: https://www.linkedin.com/in/ashley-koff/

 

James Maskell

Website: https://www.jamesmaskell.com/

Instagram: https://www.instagram.com/mrjamesmaskell

Facebook: https://www.facebook.com/jamesedwardmaskell/

LinkedIn: https://www.linkedin.com/in/jamesmaskell

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Hosted by the Functional Forum, Evolution of Medicine Podcast sits at the intersection of health, fitness, and alternative approaches to well-being. It’s a space for conversations that go beyond conventional treatment, exploring the ideas and practitioners actively reshaping how we think about care. Each episode features in-depth discussions with clinicians, researchers, and thought leaders who are redefining the patient journey. You’ll hear practical insights into functional medicine, preventative strategies, and the nuanced connections between lifestyle, nutrition, and long-term health. This podcast digs into the real-world application of these evolving principles, offering listeners a forward-looking perspective on what it means to truly support the body's innate capacity for healing. Tune in for a thoughtful exploration of the systems, science, and stories driving this shift, providing a valuable resource for both healthcare professionals and anyone invested in taking a more active role in their own wellness. The dialogue here is dedicated to understanding the full spectrum of what modern medicine can become.
Author: Language: English Episodes: 50

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