#39B - Abnormal Uterine Bleeding (Part II)

#39B - Abnormal Uterine Bleeding (Part II)

Author: 1PM July 26, 2026 Duration: 43:50

First Principles of Abnormal Uterine Bleeding (AUB)

In this episode, we're going to break it all down from first principles. We'll walk through how to take a focused history without getting lost in the menstrual timeline, what investigations actually matter (and which ones don't), and how management changes depending on what's causing the bleeding.

As always, this isn't about memorising endless lists. It's about understanding the why behind the questions you ask and the tests you order, so the next time you're on ward rounds or in an OSCE, you'll know exactly where to start.

So grab your coffee, your notebook, or your favourite study snack, and let's dive into abnormal uterine bleeding—because periods might be monthly, but OSCEs can ask about them any day of the year!


Disclaimer: This episode was recorded on 8 May 2026. At the time of recording, the condition now known as Polyendocrine Metabolic Ovarian Syndrome (PMOS) was referred to as Polycystic Ovary Syndrome (PCOS). Following the official nomenclature change announced on 12 May 2026, the term PMOS is now preferred. References to "PCOS" in this episode reflect the terminology that was in use at the time of recording.


Check out the online note here: ⁠https://1pm.notion.site/39-Abnormal-Uterine-Bleeding-37def1d0b55f803e8439dbd37275bf2c⁠


=== Other Links ===

1PM Website

Check out our new website⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠1pm.wiki⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ for the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Notion document⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, free Anki flashcards, and podcast episodes.

Instagram 

⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/firstprinciplesofmedicine/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠


Recorded 8 May 2026.

Hosts: Angela Goh, Julia Jolly, Jasmyne Le

Produced by Angela Goh.


If you have any ideas or feedback, comment on this Notion document, or shoot us an email at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠hello@1pm.wiki⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

© First Principles of Medicine 2026



There's a particular kind of pressure in medicine, where complex problems demand clear thinking under duress. First Principles of Medicine is built for those moments. Instead of offering memorized lists or surface-level reviews, this podcast from 1PM digs down to the foundational concepts that govern how the human body works and how we approach its care. Each episode takes a seemingly intricate topic in health, fitness, or clinical medicine and deconstructs it into its most basic, undeniable components. What you'll hear are conversations and analyses that rebuild understanding from the ground up. The aim is to equip you with a flexible framework, a way of thinking that holds up when straightforward answers aren't available. By consistently returning to these core tenets, the podcast fosters a deeper, more intuitive grasp of medical science. Whether you're a student, a practitioner, or simply someone fascinated by how we heal and function, tuning in provides a mental toolkit. It's about cultivating the confidence to reason through uncertainty, using first principles as a reliable guide. This isn't just another medical show; it's an ongoing exercise in intellectual clarity for practical application.
Author: Language: English Episodes: 50

First Principles of Medicine
Podcast Episodes
#30B - Shock...in 5 minutes! [not-audio_url] [/not-audio_url]

Duration: 5:25
The First Principles of Shock (Summary): a 5 minute summary covering the causes, symptoms, types, and management of shock.⁠1PM Notion: Shock⁠=== Other Links ===Check out our new website⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠1pm.wiki⁠⁠⁠⁠⁠⁠⁠⁠⁠…
#30A - Shock! When oxygen delivery begins to stop [not-audio_url] [/not-audio_url]

Duration: 34:00
The First Principles of Shock: Join us as we break down the essentials, covering everything from the causes and symptoms, to the latest management strategies. We go through all of the shocking details as well as a case e…
#29B - Pneumonia...OSCE-style summary in 7 minutes! [not-audio_url] [/not-audio_url]

Duration: 7:41
The First Principles of Pneumonia: Join us as we break down the essentials, covering everything from the causes and symptoms to the latest management strategies. Whether it's community-acquired, hospital-acquired, or the…
#29A - Pneumonia: Did you eat any steak? [not-audio_url] [/not-audio_url]

Duration: 46:07
The First Principles of Pneumonia: Join us as we break down the essentials, covering everything from the causes and symptoms to the latest management strategies. Whether it's community-acquired, hospital-acquired, or the…
#28B - PPH: OSCE-style summary [not-audio_url] [/not-audio_url]

Duration: 5:42
The First Principles of PPH: Join us as we dive into the 4 T's – Tone, Trauma, Tissue, and Thrombin – the key culprits behind excessive bleeding. From uterine atony to clotting issues, we’ll walk you through each cause a…
#28A - PPH: Push! Push! Harder! [not-audio_url] [/not-audio_url]

Duration: 34:10
The First Principles of PPH: Join us as we dive into the 4 T's – Tone, Trauma, Tissue, and Thrombin – the key culprits behind excessive bleeding. From uterine atony to clotting issues, we’ll walk you through each cause a…
#27B - Vertigo: OSCE-style summary [not-audio_url] [/not-audio_url]

Duration: 3:12
The First Principles of Vertigo: Feeling dizzy? Or did you just get hit in the ear? Join us for a spin on the world of vertigo: whether it's crystals in your ears or something more sinister, we've got you covered with ti…
#27A - Vertigo: Did you get hit in the ear? [not-audio_url] [/not-audio_url]

Duration: 30:30
The First Principles of Vertigo: Feeling dizzy? Or did you just get hit in the ear? Join us for a spin on the world of vertigo: whether it's crystals in your ears or something more sinister, we've got you covered with ti…
#26B - Anemia...in 5 minutes! [not-audio_url] [/not-audio_url]

Duration: 4:13
The First Principles of Anemia from the beginning: erythropoiesis, the components of a full blood count, and the general approach to the MCV. Dive into the world of hypersegmented neutrophils and hyperdynamic states – it…
#26A - Anemia: Hyperdynamic & Hypersegmented [not-audio_url] [/not-audio_url]

Duration: 39:57
The First Principles of Anemia from the beginning: erythropoiesis, the components of a full blood count, and the general approach to the MCV. Dive into the world of hypersegmented neutrophils and hyperdynamic states – it…