#40 - Anaphylaxis: Don't Bee Alarmed!

#40 - Anaphylaxis: Don't Bee Alarmed!

Author: 1PM August 9, 2026 Duration: 28:45

First Principles of Anaphylaxis

Anaphylaxis is one of those conditions you never want to miss, but it can be stressful knowing exactly what to do when every second counts. In this episode, we break it all down from first principles.

We'll cover how to recognise anaphylaxis early, what's actually happening in the body, why adrenaline is the treatment of choice, and the key steps in management. As always, this isn't about memorising guidelines, it's about understanding the why behind your decisions, so you'll feel more confident in OSCEs, on the wards, and in clinical practice.

So grab your matcha, your laptop, or your favourite study snack (just maybe double check it isn't hiding any peanuts 🥜), and let's dive into anaphylaxis. From airway and breathing checks to adrenaline and beyond, because knowing what to do in those first few moments can make all the difference.


=== Other Links ===

Notion notes: https://app.notion.com/p/1pm/40-Anaphylaxis-3b9ef1d0b55f801dbfb1f285f3de9da9?source=copy_link


================

Recording date: 27/5/2026

Guests: Angela Goh, Julia Jolly, and Jasmyne Le

Producer: Jasmyne Le


If you have any ideas or feedback, comment on this Notion document, or shoot us an email at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠hello@1pm.wiki⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

© First Principles of Medicine 2026


There's a particular kind of pressure in medicine, where complex problems demand clear thinking under duress. First Principles of Medicine is built for those moments. Instead of offering memorized lists or surface-level reviews, this podcast from 1PM digs down to the foundational concepts that govern how the human body works and how we approach its care. Each episode takes a seemingly intricate topic in health, fitness, or clinical medicine and deconstructs it into its most basic, undeniable components. What you'll hear are conversations and analyses that rebuild understanding from the ground up. The aim is to equip you with a flexible framework, a way of thinking that holds up when straightforward answers aren't available. By consistently returning to these core tenets, the podcast fosters a deeper, more intuitive grasp of medical science. Whether you're a student, a practitioner, or simply someone fascinated by how we heal and function, tuning in provides a mental toolkit. It's about cultivating the confidence to reason through uncertainty, using first principles as a reliable guide. This isn't just another medical show; it's an ongoing exercise in intellectual clarity for practical application.
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