35. The Science Showing Seed Oils Are The Drivers Of Metabolic Disease With Dr. Cate Shanahan

In this eye-opening episode of Healthy AF, Zane sits down with renowned physician and author Dr. Cate Shanahan to expose what might be the biggest hidden driver of metabolic disease today: seed oils. Dr. Cate breaks down the hard science behind how oxidative stress—not sugar—is at the root of most chronic diseases, and why the most oxidized ingredient in the American diet is also the most overlooked.

You'll learn how seed oils create toxic byproducts, disrupt energy production at the cellular level, and set off a cascade of free radical damage that leads directly to insulin resistance. From debunking myths around omega-6s to explaining why most antioxidant supplements are useless, this conversation reframes the conversation around fat, inflammation, and what's truly making us sick.

🎧 Tune in to hear how ditching seed oils could be the most powerful change you make for your metabolic health—backed by science, not ideology.

What You'll Learn in This Episode:

• Why oxidative stress—not sugar—is the root cause of modern disease
• How seed oils fuel metabolic dysfunction through toxic byproducts
• The real formation of insulin resistance (it's not what you've been told)
• Why PUFA (polyunsaturated fats) + free radicals = a metabolic disaster
• Why omega-6 in whole foods isn't the problem
• The myth of omega-6 to omega-3 ratios causing disease
• Why most antioxidant supplements aren't worth your money
• How dietary dogma has buried real science about fats and health
  
  

🔥 If you've been told seed oils are heart-healthy, this episode will challenge everything. Share it with a friend, subscribe, and leave a review to help more people take back control of their metabolic health.

LINKS:

• https://drcate.com/the-energy-model-of-insulin-resistance-weight
• IG: @‌drcateshanahan
• https://free40plan.com

Episode Minute By Minute Recap:

• 00:00 – Meet Dr. Cate Shanahan and the seed oil epidemic
• 03:00 – What is oxidative stress and why it's worse than sugar
• 06:30 – PUFA and the free radical cascade
• 10:00 – How seed oils disrupt energy and raise blood sugar
• 13:00 – Gluconeogenesis and the formation of insulin resistance
• 17:00 – Why omega-6 in real food isn't the enemy
• 21:00 – Most antioxidants don't work—here's why
• 25:00 – How metabolism breaks down when cells can't make energy
• 28:00 – Whole food fats vs. extracted oils: what's the difference?
• 32:00 – The diet wars: how ideology is blocking science
• 35:00 – Final thoughts and Dr. Cate's call to change the conversation