Bacteriophages

Bacteriophages

Author: BBC Radio 4 August 1, 2024 Duration: 50:43

Melvyn Bragg and guests discuss the most abundant lifeform on Earth: the viruses that 'eat' bacteria. Early in the 20th century, scientists noticed that something in their Petri dishes was making bacteria disappear and they called these bacteriophages, things that eat bacteria. From studying these phages, it soon became clear that they offered countless real or potential benefits for understanding our world, from the tracking of diseases to helping unlock the secrets of DNA to treatments for long term bacterial infections. With further research, they could be an answer to the growing problem of antibiotic resistance.

With

Martha Clokie Director for the Centre for Phage Research and Professor of Microbiology at the University of Leicester

James Ebdon Professor of Environmental Microbiology at the University of Brighton

And

Claas Kirchhelle Historian and Chargé de Recherche at the French National Institute of Health and Medical Research’s CERMES3 Unit in Paris.

Producer: Simon Tillotson

In Our Time is a BBC Studios Audio Production

Reading list:

James Ebdon, ‘Tackling sources of contamination in water: The age of phage’ (Microbiologist, Society for Applied Microbiology, Vol 20.1, 2022)

Thomas Häusler, Viruses vs. Superbugs: A Solution to the Antibiotics Crisis? (Palgrave Macmillan, 2006)

Tom Ireland, The Good Virus: The Untold Story of Phages: The Mysterious Microbes that Rule Our World, Shape Our Health and Can Save Our Future (Hodder Press, 2024)

Claas Kirchhelle and Charlotte Kirchhelle, ‘Northern Normal–Laboratory Networks, Microbial Culture Collections, and Taxonomies of Power (1939-2000)’ (SocArXiv Papers, 2024)

Dmitriy Myelnikov, ‘An alternative cure: the adoption and survival of bacteriophage therapy in the USSR, 1922–1955’ (Journal of the History of Medicine and Allied Sciences 73, no. 4, 2018)

Forest Rohwer, Merry Youle, Heather Maughan and Nao Hisakawa, Life in our Phage World: A Centennial Field Guide to Earth’s most Diverse Inhabitants (Wholon, 2014)

Steffanie Strathdee and Thomas Patterson (2019) The Perfect Predator: A Scientist’s Race to Save Her Husband from a Deadly Superbug: A Memoir (Hachette Books, 2020)

William C. Summers, Félix d`Herelle and the Origins of Molecular Biology (Yale University Press, 1999)

William C. Summers, The American Phage Group: Founders of Molecular Biology (University Press, 2023)


For anyone with a restless mind, the weekly In Our Time podcast from BBC Radio 4 offers a deep and engaging conversation across the vast terrain of human thought and experience. Host Misha Glenny guides a panel of distinguished academics, not in lecture format, but through a lively, accessible discussion where ideas genuinely collide and unfold. You might find yourself immersed in the complex legacy of a figure like Napoleon one week, and the next be untangling the scientific principles of photosynthesis or the philosophical arguments of the Enlightenment. The scope is deliberately broad, covering history, religion, culture, science, and philosophy, because understanding one often requires context from another. What you hear is the genuine process of exploration-the questions, the debates, and the connections made in real time by leading experts. It’s the kind of podcast that doesn’t just recount the Sack of Rome or the intricacies of Russian court politics, but examines why these moments mattered and how their echoes are still felt. The result is a consistently stimulating hour that treats listeners as curious equals, offering the intellectual satisfaction of following a great conversation to its illuminating conclusion.
Author: Language: English Episodes: 100

In Our Time
Podcast Episodes
Dragons [not-audio_url] [/not-audio_url]

Duration: 46:13
Melvyn Bragg and guests explore dragons, literally and symbolically potent creatures that have appeared in many different guises in countries and cultures around the world. Sometimes compared to snakes, alligators, lions…
Barbour's 'Brus' [not-audio_url] [/not-audio_url]

Duration: 49:26
Melvyn Bragg and guests discuss John Barbour's epic poem The Brus, or Bruce, which he wrote c1375. The Brus is the earliest surviving poem in Older Scots and the only source of many of the stories of King Robert I of Sco…
The Evolution of Lungs [not-audio_url] [/not-audio_url]

Duration: 48:24
Melvyn Bragg and guests discuss the evolution of lungs and of the first breaths, which can be traced back 400 million years to when animal life spread from rock pools and swamps onto land, as some fish found an evolution…
The Vienna Secession [not-audio_url] [/not-audio_url]

Duration: 54:11
In 1897, Gustav Klimt led a group of radical artists to break free from the cultural establishment of Vienna and found a movement that became known as the Vienna Secession. In the vibrant atmosphere of coffee houses, Fre…
Hypnosis [not-audio_url] [/not-audio_url]

Duration: 45:30
Ever since Franz Anton Mesmer induced trance-like states in his Parisian subjects in the late eighteenth century, dressed in long purple robes, hypnosis has been associated with performance, power and the occult. It has…
Paul von Hindenburg [not-audio_url] [/not-audio_url]

Duration: 52:09
Melvyn Bragg and guests discuss the life and role of one of the most significant figures in early 20th Century German history. Paul von Hindenburg (1847-1934) had been famous since 1914 as the victorious commander at the…
Copyright [not-audio_url] [/not-audio_url]

Duration: 1:00:19
In 1710, the British Parliament passed a piece of legislation entitled An Act for the Encouragement of Learning. It became known as the Statute of Anne, and it was the world’s first copyright law. Copyright protects and…
Lise Meitner [not-audio_url] [/not-audio_url]

Duration: 57:22
Melvyn Bragg and guests discuss the decisive role of one of the great 20th Century physicists in solving the question of nuclear fission. It is said that Meitner (1878-1968) made this breakthrough over Christmas 1938 whi…
The Korean Empire [not-audio_url] [/not-audio_url]

Duration: 47:40
Melvyn Bragg and guests discuss Korea's brief but significant period as an empire as it moved from the 500-year-old dynastic Joseon monarchy towards modernity. It was in October 1897 that King Gojong declared himself Emp…
Molière [not-audio_url] [/not-audio_url]

Duration: 51:24
Melvyn Bragg and guests discuss one of the great figures in world literature. The French playwright Molière (1622-1673) began as an actor, aiming to be a tragedian, but he was stronger in comedy, touring with a troupe fo…