Bacteriophages

Bacteriophages

Author: BBC Radio 4 August 1, 2024 Duration: 50:43

Melvyn Bragg and guests discuss the most abundant lifeform on Earth: the viruses that 'eat' bacteria. Early in the 20th century, scientists noticed that something in their Petri dishes was making bacteria disappear and they called these bacteriophages, things that eat bacteria. From studying these phages, it soon became clear that they offered countless real or potential benefits for understanding our world, from the tracking of diseases to helping unlock the secrets of DNA to treatments for long term bacterial infections. With further research, they could be an answer to the growing problem of antibiotic resistance.

With

Martha Clokie Director for the Centre for Phage Research and Professor of Microbiology at the University of Leicester

James Ebdon Professor of Environmental Microbiology at the University of Brighton

And

Claas Kirchhelle Historian and Chargé de Recherche at the French National Institute of Health and Medical Research’s CERMES3 Unit in Paris.

Producer: Simon Tillotson

In Our Time is a BBC Studios Audio Production

Reading list:

James Ebdon, ‘Tackling sources of contamination in water: The age of phage’ (Microbiologist, Society for Applied Microbiology, Vol 20.1, 2022)

Thomas Häusler, Viruses vs. Superbugs: A Solution to the Antibiotics Crisis? (Palgrave Macmillan, 2006)

Tom Ireland, The Good Virus: The Untold Story of Phages: The Mysterious Microbes that Rule Our World, Shape Our Health and Can Save Our Future (Hodder Press, 2024)

Claas Kirchhelle and Charlotte Kirchhelle, ‘Northern Normal–Laboratory Networks, Microbial Culture Collections, and Taxonomies of Power (1939-2000)’ (SocArXiv Papers, 2024)

Dmitriy Myelnikov, ‘An alternative cure: the adoption and survival of bacteriophage therapy in the USSR, 1922–1955’ (Journal of the History of Medicine and Allied Sciences 73, no. 4, 2018)

Forest Rohwer, Merry Youle, Heather Maughan and Nao Hisakawa, Life in our Phage World: A Centennial Field Guide to Earth’s most Diverse Inhabitants (Wholon, 2014)

Steffanie Strathdee and Thomas Patterson (2019) The Perfect Predator: A Scientist’s Race to Save Her Husband from a Deadly Superbug: A Memoir (Hachette Books, 2020)

William C. Summers, Félix d`Herelle and the Origins of Molecular Biology (Yale University Press, 1999)

William C. Summers, The American Phage Group: Founders of Molecular Biology (University Press, 2023)


For anyone with a restless mind, the weekly In Our Time podcast from BBC Radio 4 offers a deep and engaging conversation across the vast terrain of human thought and experience. Host Misha Glenny guides a panel of distinguished academics, not in lecture format, but through a lively, accessible discussion where ideas genuinely collide and unfold. You might find yourself immersed in the complex legacy of a figure like Napoleon one week, and the next be untangling the scientific principles of photosynthesis or the philosophical arguments of the Enlightenment. The scope is deliberately broad, covering history, religion, culture, science, and philosophy, because understanding one often requires context from another. What you hear is the genuine process of exploration-the questions, the debates, and the connections made in real time by leading experts. It’s the kind of podcast that doesn’t just recount the Sack of Rome or the intricacies of Russian court politics, but examines why these moments mattered and how their echoes are still felt. The result is a consistently stimulating hour that treats listeners as curious equals, offering the intellectual satisfaction of following a great conversation to its illuminating conclusion.
Author: Language: English Episodes: 100

In Our Time
Podcast Episodes
Napoleon's Hundred Days [not-audio_url] [/not-audio_url]

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Melvyn Bragg and guests discuss the Serbian-American inventor Nikola Tesla (1856-1943) and his role in the development of electrical systems towards the end of the nineteenth century. He made his name in New York in the…
The Kalevala [not-audio_url] [/not-audio_url]

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Melvyn Bragg and guests discuss the Finnish epic poem that first appeared in print in 1835 in what was then the Grand Duchy of Finland, part of the Russian Empire and until recently part of Sweden. The compiler of this e…
Julian the Apostate [not-audio_url] [/not-audio_url]

Duration: 50:14
Melvyn Bragg and guests discuss the last pagan ruler of the Roman Empire. Fifty years after Constantine the Great converted to Christianity and introduced a policy of tolerating the faith across the empire, Julian (c.331…
The Waltz [not-audio_url] [/not-audio_url]

Duration: 52:12
Melvyn Bragg and guests discuss the dance which, from when it reached Britain in the early nineteenth century, revolutionised the relationship between music, literature and people here for the next hundred years. While i…
The Mokrani Revolt [not-audio_url] [/not-audio_url]

Duration: 57:32
Melvyn Bragg and guests discuss the revolt that broke out in 1871 in Algeria against French rule, spreading over hundreds of miles and countless towns and villages before being brutally suppressed. It began with the powe…
Heisenberg's Uncertainty Principle [not-audio_url] [/not-audio_url]

Duration: 58:02
Melvyn Bragg and guests discuss the German physicist who, at the age of 23 and while still a student, effectively created quantum mechanics for which he later won the Nobel Prize. Werner Heisenberg made this breakthrough…
The Sack of Rome 1527 [not-audio_url] [/not-audio_url]

Duration: 46:32
Melvyn Bragg and guests discuss the infamous assault of an army of the Holy Roman Emperor on the city of Rome in 1527. The troops soon broke through the walls of this holy city and, with their leader shot dead early on,…
Alice's Adventures in Wonderland [not-audio_url] [/not-audio_url]

Duration: 49:58
Melvyn Bragg and guests discuss Lewis Carroll's book which first appeared in print in 1865 with illustrations by John Tenniel. It has since become one of the best known works in English, captivating readers who follow yo…