February 10, 2026: Amyloidosis in Focus: Diagnosis Delays, Early Treatment, and What Clinicians Must Know | JACC This Week

February 10, 2026: Amyloidosis in Focus: Diagnosis Delays, Early Treatment, and What Clinicians Must Know | JACC This Week

Author: American College of Cardiology February 10, 2026 Duration: 14:57

In this episode of JACC This Week, Dr. Harlan M. Krumholz and Dr. Carolyn S.P. Lam discuss a dedicated issue of JACC focused on cardiac amyloidosis—one of the fastest-evolving areas in cardiovascular medicine.
They explore new evidence highlighting significant delays in diagnosing ATTR cardiomyopathy, the early divergence of mortality benefit with timely treatment, and why time to diagnosis is no longer a neutral factor. The conversation also examines secondary analyses from major clinical trials, practical guidance for amyloidosis evaluation and management, and Dr. Krumholz's Editor's Page on "computable diagnosis" as a moral imperative.
This episode places emerging science in clinical context, emphasizing urgency, equity, and how clinicians should be thinking differently about diagnosis, staging, and access to therapy in amyloid heart disease.
Read Full issue here: https://www.jacc.org/toc/jacc/87/5
Keywords: cardiac amyloidosis, amyloid heart disease, ATTR cardiomyopathy, computable diagnosis


Every week, the editors of one of the world's leading cardiology journals sit down for a conversation that goes beyond the printed page. JACC This Week, from the American College of Cardiology, brings together Editor-in-Chief Dr. Harlan Krumholz and Senior Consulting Editor Dr. Carolyn S.P. Lam. Their discussions provide essential context for the complex research published in the Journal of the American College of Cardiology, translating high-level science into meaningful insights. You’ll hear them dissect new studies, debate emerging trends, and explore the real-world implications of the latest findings in cardiovascular medicine. This isn't just a summary of the issues; it's a dialogue about how evidence is shaping modern heart care, from prevention to advanced intervention. The podcast serves as a direct line to the experts who are curating the science that defines global standards. Each episode feels like joining an informed, behind-the-scenes editorial meeting, where the nuances of patient care and clinical practice are thoughtfully examined. For anyone invested in cardiology-whether a practicing clinician, a researcher, or a dedicated student-this regular audio companion offers clarity and a deeper understanding of the forces driving the field forward. It’s where the published data meets practical conversation, all through the accessible format of a weekly podcast.
Author: Language: English Episodes: 100

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