Inhaled Treprostinil for Pulmonary Hypertension due to Interstitial Lung Disease, Omecamtiv Mecarbil for Systolic Heart Failure (HFrEF)

Inhaled Treprostinil for Pulmonary Hypertension due to Interstitial Lung Disease, Omecamtiv Mecarbil for Systolic Heart Failure (HFrEF)

Author: Stephen Jenkins, MD, Austin Rupp, MD January 21, 2021 Duration: 35:37
Today I am joined by pulmonary hypertension and heart failure expert, Dr. John Ryan, to talk about inhaled treprostinil for pulmonary hypertension due to ILD, and a new cardiac myosin activator, omecamtiv mecarbil, for treatment of systolic heart failure. Check it out! Treprostinil for Pulmonary Hypertension due to ILD Omecamtiv Mecarbil for Systolic Heart Failure Music from https://filmmusic.io "Sneaky Snitch" by Kevin MacLeod (https://incompetech.com) License: CC BY (ht...

Keeping up with the flood of new medical research can feel like a full-time job on top of your actual one. That’s where Last Week in Medicine comes in. Hosted by practicing physicians Stephen Jenkins and Austin Rupp, this weekly audio digest is built for clinicians, students, and anyone deeply interested in evidence-based medicine who needs a practical filter for the noise. Instead of spending hours scrolling through tables of contents, you get a curated review of significant findings from top-tier journals like The New England Journal of Medicine, The Lancet, and the JAMA Network, all discussed in a conversational, accessible tone. Each episode breaks down the methodology and clinical implications of recent studies, offering context you won’t find in an abstract. It’s designed to fit into a commute or a workout, transforming dense literature into actionable insight. By tuning in, you’re not just getting updates; you’re hearing two doctors analyze what these advances mean for real-world practice, from hospital medicine to outpatient care. This podcast serves as your ongoing medical education, covering a broad spectrum that includes mental health, fitness, and alternative approaches, all through a rigorous, internal medicine lens. Let Drs. Jenkins and Rupp do the reading, so you can spend your time applying what matters.
Author: Language: en-us Episodes: 67

Last Week in Medicine
Podcast Episodes
Early Vasopressors and Restrictive Fluids in Septic Shock (CLOVERS), Furosemide vs Torsemide in Heart Failure (TRANSFORM-HF), Aspirin vs Enoxaparin after Extremity Fracture (PREVENT CLOT), Haloperidol for ICU Delirium (AID-ICU) [not-audio_url] [/not-audio_url]

Duration: 51:05
We're back with Season 4! Sorry for the unplanned hiatus. Today we talk about the CLOVERS trial, which tested the hypothesis that early vasopressors and restrictive fluid would be superior to liberal fluids plus rescue v…
SGLT2 Inhibitors for Acute Heart Failure, SGLT2 Inhibitors vs Metformin, High Dose Dexamethasone for COVID-19 in ICU, Isolated Distal DVT, Monkeypox, Blood Donor Sex and Mortality, Outcomes in Surgeons Who Operate the Night Before [not-audio_url] [/not-audio_url]

Duration: 44:36
Today we have a couple special guests under the age of 2. Birdie and Gus! Do SGLT2 inhibitors improve diuresis in acute heart failure? Are they better than metformin for reducing cardiovascular mortality? Is high dose de…
Restrictive Fluids in Septic Shock, Short vs Standard Antibiotics in Neutropenic Fever, IV Vitamin C for Septic Shock, Hospitalist Workload and Patient LOS, Fluid Bolus for Intubation, General Internist Practice Choices [not-audio_url] [/not-audio_url]

Duration: 54:50
Today we are joined by Dr. Brian Locke to talk about multiple new critical care trials, including the CLASSIC trial of a restrictive vs standard fluid strategy, the LOVIT trial of vitamin C in septic shock, and the PREPA…
Inpatient Management of Opioid Use Disorder, Hep C Treatment in IVDU, Final SOLIDARITY Results for Remdesivir, TAVI for Moderate Risk Severe AS, Mediterranean Diet vs Low Fat Diet, Steroids for IgA Nephropathy, GLP-1s and Gallbladder Disease [not-audio_url] [/not-audio_url]

Duration: 58:45
Today we had Dr. Patricia Liu to talk about a new study from Journal of Hospital Medicine on the management of opioid use disorder in the hospital. And then we got a little carried away covering way too many articles! In…