Why do healthy people still get Alzheimer’s disease? | Dr Darshan Shah

Why do healthy people still get Alzheimer’s disease? | Dr Darshan Shah

Author: Sarah Ann Macklin February 9, 2026 Duration: 4:28

Watch the FULL podcast here: https://youtu.be/qHFymGgsYyE


Can you do everything right and still face Alzheimer’s risk? It can happen, and we discuss how environmental toxins, metabolic health, and shifting hormones may play a role. This clip explores two grandmothers with opposite lifestyles, highlighting possible factors like hemoglobin A1c, menopause-related drops in estrogen, and other hormones including IGF-1 and thyroid. We also consider genetic resilience and detox capacity, and why relying on luck isn’t wise. Women are addressed directly, with advice to see a good hormone doctor during perimenopause and menopause.

Dr Darshan Shah in conversation with Sarah Ann


Listen to the full episode⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠


Watch the full episode on YouTube ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠⁠⁠⁠

***

This episode is sponsored by:

NOWATCH: The compassionate health trackerConnecting body and mind with unique stress recovery insights so you can live fully today15% off with code LWBW15 at https://nowatch.com/


Mojo: the app for expert-led courses in better sex.Learn from world-class sex therapists and relationship experts with courses tailored to your needs.15% off with code LiveWell15 at mymojo.com/livewellbewell


***


The Great British Veg OutHow to support your gut, energy, and hormones by eating more — not less.👉 https://sarahmacklin.substack.com/p/the-great-british-veg-outReset Your HealthIf your body feels off after stress, travel, or burnout — this is where to start.👉 https://sarahmacklin.substack.com/s/reset-your-health-in-30-days


👉 Practical beats perfect.Here’s a free 5-recipe PDF I use to support energy and stress during busy weeks.https://sarahannmacklin.com/5_free_recipes

👉 If this resonates, you can join the thousands who readThe Compassionate Cure each week.https://sarahmacklin.substack.com/


**


Let’s be friends!

📷 Instagram: https://www.instagram.com/sarahannmacklin/

📹 Subscribe: http://www.youtube.com/@livewellbewellsarah

🐦 Twitter: https://x.com/SarahAnnMacklin

📱 TikTok: https://www.tiktok.com/@livewellbewellpodcast

💌 Newsletter: https://sarahmacklin.substack.com/


There's a lot of noise out there about what it means to be healthy, and Live Well Be Well with Sarah Ann Macklin cuts straight through it. Sarah Ann brings a grounded perspective shaped by both personal experience and formal study, moving beyond quick fixes to explore what sustainable wellness actually looks like. Each conversation in this podcast feels like a thoughtful exploration rather than a lecture, tackling the interconnected areas of holistic health, practical nutrition, and realistic lifestyle shifts. You'll hear from a range of insightful guests alongside Sarah Ann's own reflections, all aimed at making sense of the information overload. The tone is refreshingly human-this isn't about perfection, but about finding a smarter, more integrated approach to everyday living. Tuning into this podcast feels like gaining a knowledgeable, empathetic friend who believes that feeling well shouldn't feel like a constant struggle. It’s a space for anyone wanting to move past the confusion and cultivate a genuine sense of vitality that fits into a real, busy life.
Author: Language: English Episodes: 100

Live Well Be Well with Sarah Ann Macklin | Health, Lifestyle, Nutrition
Podcast Episodes
Why Being Truly Seen Feels So Terrifying for Women | Paul Brunson [not-audio_url] [/not-audio_url]

Duration: 11:53
Are you wondering how dating has changed since 2008, and why authenticity now matters so much? In this conversation, we explore how the main way people met partners used to be through work or church, compared with today…