Why You’re Tired, Gaining Weight & Aging Faster - Fix Metabolic Health | Dr Darshan Shah

Why You’re Tired, Gaining Weight & Aging Faster - Fix Metabolic Health | Dr Darshan Shah

Author: Sarah Ann Macklin December 10, 2025 Duration: 1:18:44

👉 Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. https://sarahmacklin.substack.com/


Longevity is everywhere right now, but has it become a trend instead of a truth?


In a world overflowing with health hacks, supplements, and promises of a longer life, it has never been harder to know what actually works. Beneath the noise, there is a clear science to living well for longer, but only if we learn to tune out the hype and return to what our biology has been asking of us all along.


Today I am joined by Dr. Darshan Shah, medical doctor, longevity expert, and founder of Next Health. Dr. Shah became a doctor at 21 and has since guided thousands of patients through metabolic healing, functional medicine, and evidence-based longevity. Together, we explore what truly extends your healthspan and what does not.


This conversation is a practical and compassionate look at longevity, what it means, where to begin, and why most people focus on the wrong things. Dr. Shah breaks longevity into a simple health pyramid, starting with foundational habits, then biomarkers, hormones, detoxification, brain health, and emerging therapies such as peptides.


Here’s What We Dive Into:

- What longevity truly means, and why adding years is different from adding healthy years.

- Why metabolic health is the most important predictor of long term wellbeing.

- How simple habits before and after meals support better blood sugar regulation.

- Why quarterly biomarker testing may be the most effective prevention tool we have.

- What optimal blood ranges look like, and why normal ranges are not always healthy.

- How functional medicine identifies the eight root causes behind most chronic disease.

- Why toxins, microplastics, and everyday chemicals affect long term health.

- How women’s hormones, menopause, and brain health relate to Alzheimer’s risk.

- What creatine offers for muscles, cognition, and healthy aging.

- Why peptides are rising in popularity, and how to approach them with safety and clarity.


Love,

Sarah Ann 💛


***


This episode is sponsored by:

NOWATCH: The compassionate health tracker

Connecting body and mind with unique stress recovery insights so you can live fully today

15% off with code LWBW15 at nowatch.com


***


Let’s be friends!

📷 Instagram:  / sarahannmacklin

📹 Subscribe:   / @livewellbewellsarah  

🐦 Twitter:  / sarahannmacklin  

📱 TikTok:  / sarahannnutrition  

💌 Newsletter: https://sarahmacklin.substack.com/


***


If You Enjoyed This Episode, You Might Also Like:

Improve Your Health With Biohacking: Expert Tips From Dr Molly Maloof


No.1 Gut Scientist: Insane Fiber Benefits to HEAL YOUR GUT & Beat Disease | Dr Will Bulsiewicz


***


Sign up to Sarah’s Compassionate Cure newsletter:


Science Simplified, Health Humanised. Join thousands in exploring actionable insights that prioritise compassion, clarity, and real-life impact. https://sarahmacklin.substack.com/


***


Highlights

What real longevity means and why it matters (00:00:00)

The rise of chronic illness and metabolic decline (00:03:12)

The eight root causes behind most modern diseases (00:06:58)

How continuous glucose monitors reshape daily habits (00:09:41)

Using data without falling into overwhelm (00:13:28)

The biomarkers that matter most for preventive health (00:16:44)

Why normal blood sugar is not always optimal (00:20:26)

Muscle mass and metabolism across the ageing process (00:20:26)

Creatine for strength, cognition, and longevity (00:28:14)

Toxins, microplastics, and their impact on long-term health (00:32:48)

Alzheimer’s risk and the role of women’s hormonal health (00:38:07)

Peptides, benefits, and precautions for safe use (00:47:22)


***


Love what you’re hearing?

My small ask is to please rate and review Live Well Be Well. This helps the show expand and allows me to keep producing these with the best quality guests. It means a huge amount to me, so thank you.


There's a lot of noise out there about what it means to be healthy, and Live Well Be Well with Sarah Ann Macklin cuts straight through it. Sarah Ann brings a grounded perspective shaped by both personal experience and formal study, moving beyond quick fixes to explore what sustainable wellness actually looks like. Each conversation in this podcast feels like a thoughtful exploration rather than a lecture, tackling the interconnected areas of holistic health, practical nutrition, and realistic lifestyle shifts. You'll hear from a range of insightful guests alongside Sarah Ann's own reflections, all aimed at making sense of the information overload. The tone is refreshingly human-this isn't about perfection, but about finding a smarter, more integrated approach to everyday living. Tuning into this podcast feels like gaining a knowledgeable, empathetic friend who believes that feeling well shouldn't feel like a constant struggle. It’s a space for anyone wanting to move past the confusion and cultivate a genuine sense of vitality that fits into a real, busy life.
Author: Language: English Episodes: 100

Live Well Be Well with Sarah Ann Macklin | Health, Lifestyle, Nutrition
Podcast Episodes
Why Being Truly Seen Feels So Terrifying for Women | Paul Brunson [not-audio_url] [/not-audio_url]

Duration: 11:53
Are you wondering how dating has changed since 2008, and why authenticity now matters so much? In this conversation, we explore how the main way people met partners used to be through work or church, compared with today…