Methylene Blue: Biohacker's Delight, or Playing With Fire?

Methylene Blue: Biohacker's Delight, or Playing With Fire?

Author: Chris Masterjohn, PhD September 1, 2023 Duration: 1:18:20

Get the written and referenced version here:

https://chrismasterjohnphd.substack.com/p/the-guide-to-methylene-blue

This is a 51-page guide in which you will learn the following:

The Origin of Methylene Blue

The Entry of Methylene Blue Into Medicine

From Malaria to Many Uses in Medicine

How Methylene Blue Works

A Redox-Reactive Dye

The Blue Bottle Experiment

Methylene Blue Radicals, Photoexcited States, and Demethylated Metabolites

Methylene Blue Can Oxidize and Reduce Many Targets

Methylene Blue Can Rewire the Mitochondrial Respiratory Chain

Rewiring the Respiratory Chain Does Not Make It Better

Methylene Blue Increases Hydrogen Peroxide Hydrogen Peroxide Kills Microbes, Has Hormetic Benefits, But Is Still Ultimately Toxic

Methylene Blue Causes Redox Cycling of Hemoglobin Methylene Blue Is a Strong Monoamine Oxidase A Inhibitor

Methylene Blue Inhibits Nitric Oxide Synthase Mechanistic Conclusions Is Methylene Blue Fundamentally Hormetic?

Methylene Blue Fails in Alzheimer's, and Causes a Worrisome Side Effect

Whether Methylene Blue Helps Or Hurts Depends on Whether You Need It

Natural Alternatives for Hormesis and Rewiring the Respiratory Chain

Who Should Use Methylene Blue?

Once more you can get it here:

https://chrismasterjohnphd.substack.com/p/the-guide-to-methylene-blue

Chris Masterjohn, PhD, is the Founder and Scientific Director of the mitochondria test Mitome.


Chris Masterjohn, PhD hosts Mastering Nutrition, a podcast that digs into the science of how our bodies work at a fundamental level. The focus here is on mitochondrial health-the energy powerhouses within our cells-and how optimizing them forms the cornerstone of lasting vitality. Chris brings his background as a nutrition scientist and his experience founding BioOptHealth to these conversations, which move beyond generic diet advice. Instead, the podcast explores how individual differences, informed by tools like whole genome sequencing and detailed biochemical data, can reveal personalized paths to better metabolic function. Listeners will hear deep dives into cutting-edge research, practical interpretations of complex studies, and discussions on how to apply these insights in a real-world context. This isn't about quick fixes or trending superfoods; it's about building a coherent, scientifically-grounded understanding of nutrition from the cellular level up. Each episode aims to provide the kind of nuanced, evidence-based perspective that can help you make sense of conflicting health information. Whether the topic is a specific nutrient, a metabolic pathway, or a broader principle of wellness, Chris works to translate dense science into actionable knowledge. Tune in for a thoughtful, detailed exploration of what it truly means to master your own nutritional landscape.
Author: Language: English Episodes: 712

Mastering Nutrition
Podcast Episodes
Will the booster shot be worth it? | Masterjohn Q&A Files #288 [not-audio_url] [/not-audio_url]

Duration: 14:36
Short Answer: If optimizing for efficacy, the booster shot will likely be worth it for Pfizer, whereas other vaccines don't have clear evidence of declining efficacy yet. If optimizing for safety, one should be skeptical…
How to use carbs and glycine for sleep. | Masterjohn Q&A Files #287 [not-audio_url] [/not-audio_url]

Duration: 10:52
Short Answer: To get adequate raw material for melatonin synthesis in the brain, carbs can come any time of day and are best if high-glycemic. To suppress brain histamine levels, carbs in the evening, with low protein an…
NEW! Version 7 of the COVID Guide! [not-audio_url] [/not-audio_url]

Duration: 7:43
Newly updated September 25, 2021, and now in Version 7: https://chris-masterjohn-phd.myshopify.com/products/the-food-and-supplement-guide-for-the-coronavirus This guide provides my recommendations for nutritional and her…