Methylene Blue: Biohacker's Delight, or Playing With Fire?

Methylene Blue: Biohacker's Delight, or Playing With Fire?

Author: Chris Masterjohn, PhD September 1, 2023 Duration: 1:18:20

Get the written and referenced version here:

https://chrismasterjohnphd.substack.com/p/the-guide-to-methylene-blue

This is a 51-page guide in which you will learn the following:

The Origin of Methylene Blue

The Entry of Methylene Blue Into Medicine

From Malaria to Many Uses in Medicine

How Methylene Blue Works

A Redox-Reactive Dye

The Blue Bottle Experiment

Methylene Blue Radicals, Photoexcited States, and Demethylated Metabolites

Methylene Blue Can Oxidize and Reduce Many Targets

Methylene Blue Can Rewire the Mitochondrial Respiratory Chain

Rewiring the Respiratory Chain Does Not Make It Better

Methylene Blue Increases Hydrogen Peroxide Hydrogen Peroxide Kills Microbes, Has Hormetic Benefits, But Is Still Ultimately Toxic

Methylene Blue Causes Redox Cycling of Hemoglobin Methylene Blue Is a Strong Monoamine Oxidase A Inhibitor

Methylene Blue Inhibits Nitric Oxide Synthase Mechanistic Conclusions Is Methylene Blue Fundamentally Hormetic?

Methylene Blue Fails in Alzheimer's, and Causes a Worrisome Side Effect

Whether Methylene Blue Helps Or Hurts Depends on Whether You Need It

Natural Alternatives for Hormesis and Rewiring the Respiratory Chain

Who Should Use Methylene Blue?

Once more you can get it here:

https://chrismasterjohnphd.substack.com/p/the-guide-to-methylene-blue

Chris Masterjohn, PhD, is the Founder and Scientific Director of the mitochondria test Mitome.


Chris Masterjohn, PhD hosts Mastering Nutrition, a podcast that digs into the science of how our bodies work at a fundamental level. The focus here is on mitochondrial health-the energy powerhouses within our cells-and how optimizing them forms the cornerstone of lasting vitality. Chris brings his background as a nutrition scientist and his experience founding BioOptHealth to these conversations, which move beyond generic diet advice. Instead, the podcast explores how individual differences, informed by tools like whole genome sequencing and detailed biochemical data, can reveal personalized paths to better metabolic function. Listeners will hear deep dives into cutting-edge research, practical interpretations of complex studies, and discussions on how to apply these insights in a real-world context. This isn't about quick fixes or trending superfoods; it's about building a coherent, scientifically-grounded understanding of nutrition from the cellular level up. Each episode aims to provide the kind of nuanced, evidence-based perspective that can help you make sense of conflicting health information. Whether the topic is a specific nutrient, a metabolic pathway, or a broader principle of wellness, Chris works to translate dense science into actionable knowledge. Tune in for a thoughtful, detailed exploration of what it truly means to master your own nutritional landscape.
Author: Language: English Episodes: 712

Mastering Nutrition
Podcast Episodes
7 Steps to Cure Histamine Intolerance | Chris Masterjohn Lite #95 [not-audio_url] [/not-audio_url]

Duration: 9:27
Here's a 7-step protocol to tackle histamine intolerance. Tune in to learn more! This episode is brought to you by Ancestral Supplements' "Living" Collagen. Our Native American ancestors believed that eating the organs f…
Is Alcohol Good for You? | Chris Masterjohn Lite #94 [not-audio_url] [/not-audio_url]

Duration: 10:43
Is alcohol good for you? It's clear to me that 1) alcohol is a toxin and 2) it can help with having fun, which is good for you, but in this episode I consider whether some dose of alcohol might actually be fundamentally…
Alcohol and Histamine | Chris Masterjohn Lite #93 [not-audio_url] [/not-audio_url]

Duration: 4:33
Could drinking alcohol be contributing to your allergies or histamine intolerance? When my allergies started going nuts in Greece this summer, I was drinking more alcohol. Alcohol impairs the clearance of histamine *and*…
How to Test for Histamine Intolerance | Chris Masterjohn Lite #89 [not-audio_url] [/not-audio_url]

Duration: 6:37
Do you have histamine intolerance? It could be confused with an increased burden of mast cells, one of the main types of cells that release histamine. Tune in for two lab tests that can help you tell the difference. This…
How to Manage Your Selenium Status | Chris Masterjohn Lite #87 [not-audio_url] [/not-audio_url]

Duration: 9:10
Selenium makes you resilient to all kinds of stress, including the physical attacks of infections and toxins. It keeps your nails healthy, prevents the wear and tear on your tissues as you age, keeps your body from launc…
How to Manage Your Vitamin C Status | Chris Masterjohn Lite #86 [not-audio_url] [/not-audio_url]

Duration: 10:23
Vitamin C protects against bleeding gums, makes your bones strong, helps keep you from getting sick, protects against the normal wear and tear on our tissues, helps us deal with alcohol, cigarette smoke, and toxins in ou…