Methylene Blue: Biohacker's Delight, or Playing With Fire?

Methylene Blue: Biohacker's Delight, or Playing With Fire?

Author: Chris Masterjohn, PhD September 1, 2023 Duration: 1:18:20

Get the written and referenced version here:

https://chrismasterjohnphd.substack.com/p/the-guide-to-methylene-blue

This is a 51-page guide in which you will learn the following:

The Origin of Methylene Blue

The Entry of Methylene Blue Into Medicine

From Malaria to Many Uses in Medicine

How Methylene Blue Works

A Redox-Reactive Dye

The Blue Bottle Experiment

Methylene Blue Radicals, Photoexcited States, and Demethylated Metabolites

Methylene Blue Can Oxidize and Reduce Many Targets

Methylene Blue Can Rewire the Mitochondrial Respiratory Chain

Rewiring the Respiratory Chain Does Not Make It Better

Methylene Blue Increases Hydrogen Peroxide Hydrogen Peroxide Kills Microbes, Has Hormetic Benefits, But Is Still Ultimately Toxic

Methylene Blue Causes Redox Cycling of Hemoglobin Methylene Blue Is a Strong Monoamine Oxidase A Inhibitor

Methylene Blue Inhibits Nitric Oxide Synthase Mechanistic Conclusions Is Methylene Blue Fundamentally Hormetic?

Methylene Blue Fails in Alzheimer's, and Causes a Worrisome Side Effect

Whether Methylene Blue Helps Or Hurts Depends on Whether You Need It

Natural Alternatives for Hormesis and Rewiring the Respiratory Chain

Who Should Use Methylene Blue?

Once more you can get it here:

https://chrismasterjohnphd.substack.com/p/the-guide-to-methylene-blue

Chris Masterjohn, PhD, is the Founder and Scientific Director of the mitochondria test Mitome.


Chris Masterjohn, PhD hosts Mastering Nutrition, a podcast that digs into the science of how our bodies work at a fundamental level. The focus here is on mitochondrial health-the energy powerhouses within our cells-and how optimizing them forms the cornerstone of lasting vitality. Chris brings his background as a nutrition scientist and his experience founding BioOptHealth to these conversations, which move beyond generic diet advice. Instead, the podcast explores how individual differences, informed by tools like whole genome sequencing and detailed biochemical data, can reveal personalized paths to better metabolic function. Listeners will hear deep dives into cutting-edge research, practical interpretations of complex studies, and discussions on how to apply these insights in a real-world context. This isn't about quick fixes or trending superfoods; it's about building a coherent, scientifically-grounded understanding of nutrition from the cellular level up. Each episode aims to provide the kind of nuanced, evidence-based perspective that can help you make sense of conflicting health information. Whether the topic is a specific nutrient, a metabolic pathway, or a broader principle of wellness, Chris works to translate dense science into actionable knowledge. Tune in for a thoughtful, detailed exploration of what it truly means to master your own nutritional landscape.
Author: Language: English Episodes: 712

Mastering Nutrition
Podcast Episodes
Why You Should Moderate Your Millet | Chris Masterjohn Lite #17 [not-audio_url] [/not-audio_url]

Duration: 7:20
If you eat millet or eat gluten-free bread, you should watch this video, because you could be hurting your thyroid. Access the show notes, transcript, and comments here. Chris Masterjohn, PhD, is the Founder and Scientif…
How to Read a Science Paper | Mastering Nutrition #29 [not-audio_url] [/not-audio_url]

Duration: 2:04:58
In this episode, I explain how to come up with a good question, obtain the background information you need, find research, obtain full texts, organize them, read the different sections of a paper to get the right kind of…
How to Kill a Cold With Zinc | Chris Masterjohn Lite #16 [not-audio_url] [/not-audio_url]

Duration: 6:23
Last time we talked about supporting zinc nutritional status. Today we talk about how to kill a cold with zinc. Believe it or not, the principles are completely different. Your oysters can help you get sick lest often. B…
How to Make Your Own DIY Home Air Filter | Chris Masterjohn Lite #12 [not-audio_url] [/not-audio_url]

Duration: 3:59
I currently use a Germ Guardian, but for about a decade I used this method, which is half the initial cost and one fifth the long-term maintenance costs. Access the show notes, transcript, and comments here. Chris Master…
How to Know If Coffee Can Save Your Life | Chris Masterjohn Lite #11 [not-audio_url] [/not-audio_url]

Duration: 3:50
If you're one of the 7% who have this gene, then drinking coffee may just save your life. Access the show notes, transcript, and comments here. Chris Masterjohn, PhD, is the Founder and Scientific Director of the mitocho…