What to Do About Twitching | Masterjohn Q&A Files #314

What to Do About Twitching | Masterjohn Q&A Files #314

Author: Chris Masterjohn, PhD May 8, 2023 Duration: 7:22

Question: What can be done about twitching?

Short Answer: Most twitching will be driven by glutamate/GABA balance or acetylcholine regulation, and the most likely nutritional issues are any of the electrolytes or any factor that influences energy metabolism. The best way to address it is to consider the conditions that influence it and then trial and error your way through each potential nutritional issue in order of which ones make the most sense for your individual case first.

This is a clip from a live Q&A session open to CMJ Masterpass members. In addition to this episode, you can access two other free samples using this link:

https://chrismasterjohnphd.substack.com/p/questions-on-phosphatidylcholine

In that batch of free episodes you will also find the answers to these questions:

  • Phosphatidylcholine and TMAO
  • Vitamin K2 and Undercarboxylated Osteocalcin

If you want to become a Masterpass member so you can participate in the next live Q&A, or so you can have access to the complete recording and transcript of each Q&A session, you can save 10% off the subscription price for as long as you remain a member by using this link to sign up:

https://chrismasterjohnphd.substack.com/qanda

Learn more about the Masterpass here:

https://chrismasterjohnphd.substack.com/about

This snippet is from the December 14, 2022 AMA. The full recording and transcript is reserved for Masterpass members. Here is a preview of what's included:

  • Inositol, What Is It Good For?
  • If I am at risk of heart disease, and phosphatidylcholine raises my TMAO, should I stop the supplement?
  • If undercarboxylated osteocalcin (ucOCN) has health benefits and vitamin K2 decreases it, what does that mean for vitamin K2 supplementation?
  • Maragen Calcium
  • Could slow methylation cause high selenium levels?
  • My current thoughts on cholesterol and heart disease
  • If I already have oxidative stress, what ducks should I have in a row before supplementing with iron?
  • Is it safe to take eight milligrams of zinc daily without copper?
  • What to do about developing sensitivities to an increasingly broad range of foods?
  • What else to do about hemochromatosis besides phlebotomy?
  • If gestational diabetes is just a biotin deficiency, why are women who are insulin resistant prior to pregnancy at higher risk for it, including women with PCOS?
  • What to do about chronically elevated amylase and lipase?
  • What to do about a non-drinker having very high GGT and occasionally high ALT?
  • What are the most common vitamin and mineral deficiencies?
  • What are the best supplements, vitamins, and minerals for OCD and depression?
  • What is the connection between low pyruvate and high ketones?
  • Is high LDL a concern if the carotid IMT and coronary calcium scan are clear? 
  • Do I trust food allergy tests?

Here's a link to the full AMA: https://chrismasterjohnphd.substack.com/p/recording-and-transcript-of-the-december

Access the show notes, transcript, and comments here.

Chris Masterjohn, PhD, is the Founder and Scientific Director of the mitochondria test Mitome.


Chris Masterjohn, PhD hosts Mastering Nutrition, a podcast that digs into the science of how our bodies work at a fundamental level. The focus here is on mitochondrial health-the energy powerhouses within our cells-and how optimizing them forms the cornerstone of lasting vitality. Chris brings his background as a nutrition scientist and his experience founding BioOptHealth to these conversations, which move beyond generic diet advice. Instead, the podcast explores how individual differences, informed by tools like whole genome sequencing and detailed biochemical data, can reveal personalized paths to better metabolic function. Listeners will hear deep dives into cutting-edge research, practical interpretations of complex studies, and discussions on how to apply these insights in a real-world context. This isn't about quick fixes or trending superfoods; it's about building a coherent, scientifically-grounded understanding of nutrition from the cellular level up. Each episode aims to provide the kind of nuanced, evidence-based perspective that can help you make sense of conflicting health information. Whether the topic is a specific nutrient, a metabolic pathway, or a broader principle of wellness, Chris works to translate dense science into actionable knowledge. Tune in for a thoughtful, detailed exploration of what it truly means to master your own nutritional landscape.
Author: Language: English Episodes: 712

Mastering Nutrition
Podcast Episodes
Weston Price and Beyond | Mastering Nutrition #52 [not-audio_url] [/not-audio_url]

Duration: 1:20:02
In this episode, Hilda Librada Gore of the Wise Traditions podcast interviews me about the work of Weston Price, dental researcher extraordinaire and pioneer of nutritional anthropology. In the second half, we talk about…
How to Manage Your Vitamin B6 Status | Chris Masterjohn Lite #85 [not-audio_url] [/not-audio_url]

Duration: 10:56
Vitamin B6 protects against depression, anxiety, insomnia, age-related cognitive decline, hypoglycemia, kidney stones, and the morning sickness of pregnancy. Tune in for everything you need to know about how to manage yo…
How to Manage Your Copper Status | Chris Masterjohn Lite #84 [not-audio_url] [/not-audio_url]

Duration: 11:58
Copper! Copper is needed to prevent anemia, histamine intolerance, high cholesterol, and osteoporosis, probably helps with allergies, and is needed to make you feel good overall. There's a dark side to its toxicity, but…
DON'T Count Your Collagen as Protein | Chris Masterjohn Lite #83 [not-audio_url] [/not-audio_url]

Duration: 10:14
Do you supplement with collagen? Collagen is great, and important, but you SHOULDN'T be counting it toward your protein intake. I've been seeing "collagen protein" bars around, and there's nothing inaccurate about callin…
Zinc for Heavy Metals | Chris Masterjohn Lite #82 [not-audio_url] [/not-audio_url]

Duration: 5:54
Got heavy metals? If the elevation of heavy metals is modest (for example, less than twice the upper limit of the reference range), I think it is best to use zinc supplementation as a gentle approach to help detoxify. He…
Why I DON'T Recommend Zinc Picolinate | Chris Masterjohn Lite #81 [not-audio_url] [/not-audio_url]

Duration: 9:03
There are plenty of zinc supplements out there, and while many are acceptable, I don't recommend using zinc oxide or zinc picolinate. People are often surprised that I recommend against picolinate. So, in this episode, I…
How to Supplement with Zinc | Chris Masterjohn Lite #80 [not-audio_url] [/not-audio_url]

Duration: 7:01
Wondering what the best way is to supplement with zinc? This episode covers what kind to take, what dose, when to take it, how often, with what foods or on an empty stomach, and of course how to know if you should be sup…
How to Manage Your Zinc Status | Chris Masterjohn Lite #79 [not-audio_url] [/not-audio_url]

Duration: 8:35
Zinc is needed for healthy skin, a robust immune system, sharp vision, stable blood sugar control, balanced and strong hormonal health, and far more. It's even needed for protection against the heavy metals that pollute…
7 Natural Ways to Boost Your Glutathione | Chris Masterjohn Lite #78 [not-audio_url] [/not-audio_url]

Duration: 7:13
Glutathione is a molecule you make from the protein in your diet that is incredibly important to protecting your liver, thyroid, and lungs. It's the master antioxidant of the cell, critical to detoxing and cleaning out y…
Glutathione for Asthma | Chris Masterjohn Lite #77 [not-audio_url] [/not-audio_url]

Duration: 5:51
Do you have asthma? Do you know or love someone who does? Here's how to use supplemental glutathione (reduced, liposomal, and nebulized) to help with this condition. This is the link to the episode on nitric oxide, menti…