What to Do About Your COMT Genes | Chris Masterjohn Lite #42

What to Do About Your COMT Genes | Chris Masterjohn Lite #42

Author: Chris Masterjohn, PhD January 16, 2018 Duration: 7:12

Do you have anxiety? Depression? Attention problems? Or are you worried about estrogen and cancer?

If so, listen to this podcast to learn about the role of your COMT genetics.

COMT metabolizes dopamine, estrogen, and various other things. Half of us have the genetic for intermediate activity. The other half of us are split evenly between high and low activity. When nutrition is optimal, this just leads to personality differences: with low COMT activity, you're better at focusing, but tend to ruminate on things rather than letting them go; with high COMT activity, you rarely get stuck in a rut, but you just as rarely sit down to focus on one single thing. When nutrition is off, we can go to pathological extremes, whether it's depression and anxiety on one hand, or attention deficit and hyperactivity on the other. Robust COMT activity is also needed to get rid of harmful forms of estrogen that contribute to cancer risk.

I recommend testing your COMT genes with StrateGene, which you can get here:

chrismasterjohnphd.com/strategene

To get these episodes free of ads, with transcripts, and weeks or sometimes even months before they are released to the public, along with access to monthly live Q&A sessions, sign up for the CMJ Masterpass at https://chrismasterjohnphd.com/masterpass. Use the code LITE10 to get 10% off. To make it easier to get the discount, use this link, which has the coupon already activated: https://masterpass.chrismasterjohnphd.com/cmj-masterpass/2200/buy?coupon=LITE10

For more information on how to get the StrateGene report, watch this video, the first of the three MTHFR videos:

https://chrismasterjohnphd.com/2017/12/04/know-need-care-mthfr/

Here are the two other MTHFR videos:

https://chrismasterjohnphd.com/2017/12/06/what-to-do-about-mthfr/

https://chrismasterjohnphd.com/2017/12/11/bloodwork-get-mthfr/

Access the show notes, transcript, and comments here.

Chris Masterjohn, PhD, is the Founder and Scientific Director of the mitochondria test Mitome.


Chris Masterjohn, PhD hosts Mastering Nutrition, a podcast that digs into the science of how our bodies work at a fundamental level. The focus here is on mitochondrial health-the energy powerhouses within our cells-and how optimizing them forms the cornerstone of lasting vitality. Chris brings his background as a nutrition scientist and his experience founding BioOptHealth to these conversations, which move beyond generic diet advice. Instead, the podcast explores how individual differences, informed by tools like whole genome sequencing and detailed biochemical data, can reveal personalized paths to better metabolic function. Listeners will hear deep dives into cutting-edge research, practical interpretations of complex studies, and discussions on how to apply these insights in a real-world context. This isn't about quick fixes or trending superfoods; it's about building a coherent, scientifically-grounded understanding of nutrition from the cellular level up. Each episode aims to provide the kind of nuanced, evidence-based perspective that can help you make sense of conflicting health information. Whether the topic is a specific nutrient, a metabolic pathway, or a broader principle of wellness, Chris works to translate dense science into actionable knowledge. Tune in for a thoughtful, detailed exploration of what it truly means to master your own nutritional landscape.
Author: Language: English Episodes: 712

Mastering Nutrition
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