TRIFLO CARDIOVASCULAR: Deep Dive Podcast

TRIFLO CARDIOVASCULAR: Deep Dive Podcast

Author: Dr. Jeff Cole and Dr. Jeff Brown January 12, 2024 Duration: 45:38

By going back to the drawing board, has this global team of founders solved for tricuspid regurgitation, the “forgotten valve”? How far will they advance this breakthrough solution before one of the 4 major cardiovascular giants want to own it?

“Deep Dive” or uncut version of our video podcast. Drs Jeff Brown and Jeff Cole interview Frank Ahmann of Triflo Cardiovascular.

Tricuspid regurgitation (TR) affects millions of elderly patients and is associated with a significant decrease of quality of life, increased hospitalizations, and impaired survival. Symptomatic severe TR is grossly under-treated. The current leading transcatheter technologies only address a limited segment of the patient population.

Southern California - based Triflo Cardiovascular is developing the Tricuspid Flow Optimizer, a minimally invasive valve specifically ideated for TR. The minimalistic design includes an adaptive mini valve and single size transfemoral delivery system. The Optimizer works in tandem with the native valve regardless of its size and shape therefore treating a broader patient population.

First successful clinical cases have been completed indicating that the device not only reduces regurgitation, but also supports the global cardiac recovery to improve function, exercise capacity, and quality of life. Triflo Cardiovascular is gearing up to expand clinical studies and move towards future regulatory approval. They are preparing to raise a Series B round of funding.

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DISCLAIMER: Merge Medical and the podcast hosts are providing this content for informational and entertainment purposes only and are not broker dealers or registered investment advisors. We are not providing investment or legal advice. We will bring awareness to interesting projects and companies and then leave further discussion of the clinical and/or investable merits of these companies up to free discussion within the forum. Additionally, podcast participants (including the hosts) and Merge Medical forum members may or may not have a financial interest within the companies being interviewed or featured.


Hosted by physicians Dr. Jeff Cole and Dr. Jeff Brown, the Merge Medical Startup Podcast sits at a unique crossroads. It’s built for a community of clinicians and health professionals who look beyond the clinic walls, driven by curiosity about healthcare innovation, investment, and the practical business realities of medicine. Each episode stems from a deep search for the most compelling new companies and technologies emerging in the startup and growth-stage landscape. You’ll hear directly from the founders behind these ventures, getting an unfiltered look at the problems they’re solving and the journeys they’re on. To fit different listening habits, conversations are thoughtfully edited into two distinct formats. There’s a rapid-fire "10 in 10" teaser for a quick insight, alongside longer, in-depth interviews that delve into the nuances of building a health-focused business. This podcast provides a grounded, professional perspective on where medicine meets the market, offering a clear window into the ideas and people shaping the future of care.
Author: Language: English Episodes: 39

Merge Medical Startup Podcast
Podcast Episodes
MICARE PATH: 10 in 10 Podcast [not-audio_url] [/not-audio_url]

Duration: 13:04
MiCare Path is building a closer connection with an ever-growing population through its mobile health platform. Can personalized patient education and data-driven decisions result in better patient outcomes across multip…
RHINOGRAM: Deep Dive Podcast [not-audio_url] [/not-audio_url]

Duration: 1:00:58
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RHINOGRAM: 10 in 10 Podcast [not-audio_url] [/not-audio_url]

Duration: 15:06
With an open rate of 99%, there simply isn’t a better form of Healthcare communication than texting. This multi-patented secure and HIPAA-compliant solution services 13 million patients with AI-driven team-based workflow…
ENTAC MEDICAL: Deep Dive Podcast [not-audio_url] [/not-audio_url]

Duration: 44:54
Can acoustic biomarkers and AI be used to identify entry into disease state transition zones early enough to allow proactive decision making? Predict an ileus multiple days before it happens? Applications for cardiac and…
INTUSCOPE: 10 in 10 Podcast [not-audio_url] [/not-audio_url]

Duration: 10:54
Can this patented Class I FDA Device featuring a reusable blade and reusable handle make intubation easier, faster, and safer in even the most difficult patients and most challenging environments?“10 in 10” or quick-hitt…
DISCGENICS: Deep Dive Podcast [not-audio_url] [/not-audio_url]

Duration: 1:21:50
With a market cap of several hundred million, to call DiscGenics a “Startup” isn’t exactly true. This growth stage company has their eye on becoming a blockbuster (injectable) drug company. Can a new cell line (discogeni…
DISCGENICS: 10 in 10 Podcast [not-audio_url] [/not-audio_url]

Duration: 22:10
With a market cap of several hundred million, to call DiscGenics a “Startup” isn’t exactly true. This growth stage company has their eye on becoming a blockbuster (injectable) drug company. Can a new cell line (discogeni…
TECTON: Deep Dive Podcast [not-audio_url] [/not-audio_url]

Duration: 35:08
Ketones are the most pure form of energy that our body makes. Have these former Coca-Cola executives and the original founder created the ultimate multifunctional energy and health drink?“Deep Dive” or uncut version of o…