Episode 254: Picking the Right Probiotic

Are you totally confused by probiotics or not sure which one to choose? Want to ensure you are getting the best bang for your buck and that your probiotic is actually doing something? Curious about how to pulse your probiotics based on symptoms and season? Tune in to hear Ali and Becki go down the rabbit hole on strain-specific research and discuss what to look for in a probiotic, best formulas for desired clinical outcomes, and how to tell if a probiotic is good quality. 

In this episode, Ali and Becki go into detail on some of the most widely researched probiotic strains, from lactobacillus to bifidobacterium to saccharomyces boulardii and beyond. Learn about promising clinical outcomes from reduction of IBS and IBD pain, regulation of bowels post antibiotic, prevention of candida overgrowth, and yeast infection and UTI treatment. Plus we discuss thoughts on probiotics formulated with prebiotics as well as some of the new spore-based probiotics and share our current favorite cultured foods to get a daily dose of probiotics!

Also in this episode:

• 12 Week Virtual Ketosis Program - Only $99 through 9/1! 
• Episode 230: Dysbiosis through Disconnection
• Episode 198: So You’re On an Antibiotic
• Episode 174: The Dysbiosis Disease Connection and Ali’s Cleanse
• Episode 60: Dysbiosis and the Microbiome
• Episode 68: Supporting Your Immune System Naturally (Deep dive on ear infections & antibiotic use in kids)
• Episode 87: The Gut Brain Axis
• Episode 131: Candida and SIBO Deep Dive
• What is the Microbiome?
• The Role of Probiotics
• Probiotics and Immune Health 
  • Belkaid Y, Hand TW. 2014. Role of the microbiota in immunity and inflammation. Cell157: 121–141. https://doi.org/10.1016/j.cell.2014.03.011 
  • Collins, N., & Belkaid, Y. (2018). Do the Microbiota Influence Vaccines and Protective Immunity to Pathogens? Engaging Our Endogenous Adjuvants. Cold Spring Harbor perspectives in biology, 10(2), a028860. https://doi.org/10.1101/cshperspect.a028860 
  • Kim, C.H. (2018), Immune regulation by microbiome metabolites. Immunology, 154: 220-229. doi:10.1111/imm.12930 
  • Pickard, J. M., Zeng, M. Y., Caruso, R., & Núñez, G. (2017). Gut microbiota: Role in pathogen colonization, immune responses, and inflammatory disease. Immunological reviews, 279(1), 70–89. https://doi.org/10.1111/imr.12567 
• What to Look for When Choosing a Probiotic
  • ID Guarantee
• Why We Don’t Include Prebiotics in Our Probiotics
  • Phytofiber
• Strain Specific Research
  • Lactobacillus Acidophilus NCFM
    • D’Souza, B., et al. (2015), ‘Randomized controlled trial of probiotics after colonoscopy’. ANZ Journal of Surgery, doi: 10.1111/ans.13225.
    • Engelbrektson, A.L .et al., (2009). ‘Probiotics to minimize the disruption of faecal microbiota in healthy subjects undergoing antibiotic therapy’. Journal of Medical Microbiology, 58:663-670.
    • Engelbrektson, A.L. et al., (2006). ‘Analysis of treatment effects on the microbial ecology of the gastrointestinal tract’. FEMS Microbiol. Ecol. 57:239-250.
    • Faber S.E., (2003), ‘Comparison of probiotics with antibiotics to probiotics alone in treatment of diarrhea predominant IBS (D-IBS), alternating (A-IBS) and constipation (C-IBS) patients’, Gastroenterology, 124(4):A687-A688.
    • Faber, S.M., (2000). ‘Treatment of abnormal gut flora improves symptoms in patients with irritable bowel syndrome’. American Journal of Gastroenterology, 95(9):2533.
    • Forssten, S., et al., (2014). ‘Influence of a probiotic mixture on antibiotic induced microbiota disturbances’. World Journal of Gastroenterology, 20(33):11878-85.
    • Leyer, G.J., et al., (2009). ‘Probiotic Effects on Cold and Influenza-Like Symptom Incidence and Duration in Children’. Pediatrics; 124 (2): 172-179.
    • Restore Baseline Probiotic
    • Targeted Strength Probiotic - use code TARGETPRO18 for 18% off 
    • KidsBiotic
  • How to Take Probiotics With Antibiotics
  • Bifidobacterium lactis Bi-07
    • Gobel et al., (2010). ‘Probiotics to young children with atopic dermatitis: A randomized placebo-controlled trial’. International Journal of Probiotics and Prebiotics, 5(2):53-59.
    • Lammers, K.M., (2003). ‘Immunomodulatory effects of probiotic bacteria DNA: IL-1 and IL-10 response in human peripheral blood mononuclear cells’. FEMS Immunology and Medical Microbiology 38: 165-172.
    • Leyer G.J. et al., (2009). ‘Probiotic effects on cold and influenza-like symptom incidences and duration in children’. Pediatrics, 124:72-179.
    • Maneerat S. et al., (2013). ‘Consumption of Bifidobacterium lactis Bi-07 by healthy elderly adults enhances phagocytic activity of monocytes and granulocytes’ J Nutr Sci.., 2(2):e44.
    • Masco L. et al., (2004). ‘Polyphasic taxonomic analysis of Bifidobacterium animalis and Bifidobacterium lactis reveals relatedness at the subspecies level: reclassification of Bifidobacterium animalis subsp. Animalis subsp. nov. and Bifidobacterium lactis as Bifidobacterium animalis subsp. Lactis subsp. Nov’. Int. J. System. Evol. Microbiol., 54(4): 1137-1143.
  • Lactobacillus Plantarum
    • Rebuild Spectrum Probiotic
    • Post Surgical Protocol
  • Saccharomyces Boulardii
    • Abbas Z. et al., (2014), ‘Cytokine and clinical response to Saccharomyces boulardii therapy in diarrhea-dominant irritable bowel syndrome: a randomized trial’, Eur J Gastroenterol Hepatol, 26(6):630-9.
    • Akil I. et al., (2006), ‘Influence of oral intake of Saccharomyces boulardii on Escherichia coli in enteric flora’, Pediatr Nephrol, 21(6):807-10.
    • Algin C., et al. (2005) ‘Effectiveness of Bombesin and Saccharomyces boulardii against the translocation of Candida albicans in the digestive tract in immunosuppressed rats’. Surgery Today, 35: 869.
    • Bafutto M. et al., (2013), ‘Treatment of diarrhea-predominant irritable bowel syndrome with mesalazine and/or Saccharomyces boulardii’,Arq Gastroenterol, 50(4):304-9.
    • Berg R. et al., (1993), ‘Inhibition of Candida albicans translocation from the gastrointestinal tract of mice by oral administration of Saccharomcyes boulardii’. J. Infect. Dis. 168(5):1314-8.
    • Billoo A.G. et al., (2006), ‘Role of a probiotic (Saccharomyces boulardii) in management and prevention of diarrhoea’, World J Gastroenterol, 12(28):4557-60.
    • Bin, Z., et al. (2015). The Efficacy of Saccharomyces boulardii CNCM I-745 in Addition to Standard Helicobacter pylori Eradication Treatment in Children. Pediatric Gastroenterology, Hepatology & Nutrition, 18(1), 17–22.
    • Blehaut, H. et al., (1989) ‘Disposition kinetics of Saccharomyces boulardii in man and rat’. Biopharm Drug Dispos, 10: 353–364.
    • Bruggencate T., (2015), ‘The effect of a multi-strain probiotic on the resistance toward Escherichia coli challenge in a randomized, placebo-controlled, double-blind intervention study’. European Journal of Clinical Nutrition, 69:385-391.
    • Burande M.A., (2013), ‘Comparison of efficacy of Saccharomyces boulardii strain in the treatment of acute diarrhea in children: A prospective, single-blind, randomized controlled clinical trial’, J Pharmacol Pharmacother, 4(3):205-8.
    • Buts J. et al., (1993), ‘Saccharomyces boulardii for Clostridium difficile-Associated Enteropathies in Infants’. Journal of Pediatric Gastroenterology and Nutrition, 16:419-425.
  • Lactobacillus rhamnosus & Lactobacillus reuteri
    • Anukam et al., (2006), ‘Clinical study comparing probiotic Lactobacillus GR-1® and RC-14® with met*******ole vaginal gel to treat symptomatic bacterial vaginosis’. Microbes Infect.8(12-13):2772-6.
    • Anukam K.C. et al., (2006), ‘Augmentation of antimicrobial met*******ole therapy of bacterial vaginosis with oral probiotic Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14: randomized, double-blind, placebo controlled trial’. Microbes Infect. 8(6): 1450-4.
    • Anukam et al., (2009), ‘Oral use of probiotics as an adjunctive therapy to fluconazole in the treatment of yeast vaginitis: A study of Nigerian women in an outdoor clinic’. Microb. Ecol. Health Dis., 21(2):72-77.
    • Beerepoot et al., (2012), ‘Lactobacilli vs antibiotics to prevent urinary tract infections: a randomized, double-blind, noninferiority trial in postmenopausal women’. Arch. Intern. Med., 172(9):704-12.
    • Women’s Flora Probiotic
  • Bacteriophages
    • GI Clean Up
• Probiotic Challenge
• Choosing the Right Probiotic Chart
• What About Soil Based Probiotics
• Favorite Probiotic Foods

Sponsors for this Episode: 

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This episode is also sponsored by Santa Cruz Medicinals, makers of potent and affordable CBD with effective dosing. For more information check out www.scmedicinals.com and use code ALIMILLERRD for 15% off your order.