Feeling Tired? This Molecule Could Be Why After 30

Feeling Tired? This Molecule Could Be Why After 30

Author: Dear Media April 20, 2026 Duration: 1:07:27
🎟️ Don’t miss your chance to experience the Behind the Curtain tour LIVE! Grab your tickets now before they’re gone! Get yours here: https://linktr.ee/over50flourishing In this episode of Over 50 & Flourishing, I sit down with one of the leading minds in longevity science to unpack one of the most talked-about molecules in aging today: NAD. We’ve all heard the buzz, but what is NAD, and why does it matter so much as we age? From energy and brain function to hormones, skin, and metabolism, this powerful molecule plays a critical role in how our bodies function and declines significantly after our 30s. Dr. Andrew Salzman breaks down the science in a way that actually makes sense, helping us understand what’s really happening inside our cells and how it impacts aging, menopause, and overall vitality. We also dive into the connection between NAD, inflammation, the microbiome, and cellular energy, and what we can do to better support our bodies as we move through life. Dr. Andrew Salzman is a Harvard-educated physician and biomedical entrepreneur with more than 30 years of experience in drug discovery. He has published over 170 clinical studies, holds more than 50 patents, and is known for pioneering work in NAD biology, DNA repair, and longevity science. He currently serves as Chief Medical Officer at Wonderfeel, where he focuses on developing science-backed solutions for healthy aging. Subscribe and save $15 off the one-time price at https://getwonderfeel.com Custom Promo Code: FLOURISHINGOffer: Customers will receive a travel-size, seven-day Youngr™ NMN pouch with their order Campaign Duration: April 20–April 27 Keep in Touch:Website: ⁠⁠⁠⁠⁠⁠⁠https://dominiquesachse.tv/⁠⁠⁠⁠⁠⁠⁠Book: ⁠⁠⁠⁠⁠⁠⁠https://dominiquesachse.tv/book/Insta: ⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/dominiquesachse/Facebook: ⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/DominiqueSachse/TikTok: ⁠⁠⁠⁠⁠⁠⁠https://www.tiktok.com/@dominiquesachse?lang=enYouTube: ⁠⁠⁠⁠⁠⁠⁠https://www.youtube.com/@dominiquesachsetv Have a question for Dominique? Submit it here for a chance to have it answered on the show! https://forms.gle/MpTeWN1oKN8t18pm6  Interested in being featured as a guest? Please email ⁠⁠⁠⁠⁠⁠⁠courtney@dominiquesachse.tv⁠⁠⁠⁠⁠⁠⁠  We want to make the podcast even better. Help us learn how we can: ⁠⁠⁠⁠⁠⁠⁠https://bit.ly/2EcYbu4⁠⁠⁠⁠⁠⁠⁠ Please note that this episode may contain paid endorsements and advertisements for products and services. Individuals on the show may have a direct or indirect financial interest in products or services referred to in this episode. Produced by Dear Media. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Navigating life after fifty can feel like uncharted territory, but it’s also a space brimming with potential for renewal and vibrant growth. That’s the heart of Over 50 & Flourishing with Dominique Sachse. Drawing from her own journey and a career built on curiosity-first in television news and later through creating a deeply personal YouTube community-Dominique facilitates honest conversations that move far beyond the typical narratives about aging. This podcast, from Dear Media, delves into the multifaceted reality of this life chapter, exploring topics from physical health and fitness to cultural shifts, continuous education, and profound self-improvement. Listeners will hear interviews and reflections that tackle the real questions women are asking about purpose, wellness, relationships, and identity. It’s a resource for anyone ready to redefine what it means to flourish, offering practical wisdom and genuine camaraderie. Each episode aims to provide both insight and inspiration, proving that the years after fifty are not an ending, but a compelling new beginning rich with opportunity for the woman who is wise, healthy, and wonderfully aware of her own strength. Tune in for a dialogue that honors experience while eagerly exploring what comes next.
Author: Language: English Episodes: 100

Over 50 & Flourishing with Dominique Sachse
Podcast Episodes
Breaking the Silence: The Menopause Movement with Tamsen Fadal [not-audio_url] [/not-audio_url]

Duration: 40:14
Happy Monday, Over 50 & Flourishing family! I’m so excited to welcome back the incredible Tamsen Fadal to the show. Tamsen is making waves with her groundbreaking new documentary, The M Factor, which fearlessly breaks th…
Finding the Funny: Ellen Skrmetti on Comedy, Faith & Chasing Dreams [not-audio_url] [/not-audio_url]

Duration: 56:25
For the first time on Over 50 & Flourishing, I’m thrilled to sit down with a comedian! Meet Ellen Skrmetti, the Alabama-based humorist who’s captured hearts and laughs online with her viral Instagram reels. Combining sou…
Protect Your Heart: Preventive Strategies for Lifelong Health [not-audio_url] [/not-audio_url]

Duration: 58:43
Welcome back to Over 50 & Flourishing! This week, I’m joined by Dr. Tracy Paeschke, a board-certified cardiologist and health coach with a passion for preventive care. Dr. Paeschke shares actionable insights on how to pr…
Life Check-In: Leaving The News and What's Ahead in 2025 [not-audio_url] [/not-audio_url]

Duration: 54:08
Welcome to Over 50 & Flourishing! Surprise—we’re coming to you from a brand-new studio! In this episode, Courtney and I answer your burning questions, share exciting updates, and give you an exclusive sneak peek into wha…
How Functional Nutrition is Redefining Chronic Health [not-audio_url] [/not-audio_url]

Duration: 55:32
This week, I’m joined by the incredible Andrea Nakayama, a pioneering Functional Medicine Nutritionist and founder of the Functional Nutrition Alliance. Andrea is revolutionizing the way we understand and approach chroni…
Nourish to Flourish: Discover the Healing Power of Food [not-audio_url] [/not-audio_url]

Duration: 1:01:16
Today, I’m thrilled to introduce my special guest, Sarah Wragge. After years of facing chronic health challenges, Sarah embraced a holistic approach to wellness, transforming her health through the power of food. With he…
The Ultimate Dating Checklist: Must-Haves for a Meaningful Relationship [not-audio_url] [/not-audio_url]

Duration: 1:08:04
This week we welcome back the fabulous dating expert and relationship coach Laurie Gerber, who’s here to share her game-changing 'Date Like You Mean It' dating checklist. Together, we dive into four essential strategies…
Laughter & Resilience: Finding Joy in the Journey [not-audio_url] [/not-audio_url]

Duration: 53:47
October is Breast Cancer Awareness Month, and I'm honored to welcome the inspiring Julie Edelman as my guest. A bestselling author, lifestyle expert, and speaker, Julie is known for her hit book The Accidental Housewife…
Ageless Style: Dressing to Empower & Highlight Your Best Self [not-audio_url] [/not-audio_url]

Duration: 57:41
Midlife doesn’t mean we have to lose our sense of style or conform to outdated expectations. In fact, it’s a time to embrace our individuality and dress with more confidence than ever. Today, we're discussing fashion wit…
Heart and Hustle: Finding Harmony in Family and Career [not-audio_url] [/not-audio_url]

Duration: 55:03
Happy Monday, Over 50 & Flourishing community! 🌸 Today, I'm thrilled to welcome Maddy Zeringue, Head of Marketing at Merit Street Media, to the podcast! We’re diving into how working women can master the art of storytell…