Why Psychedelics Don't Always Change Us with Nigel Denning, MA, MPsych

Why Psychedelics Don't Always Change Us with Nigel Denning, MA, MPsych

Author: Lynn Marie Morski, MD, JD September 9, 2026 Duration: 35:55

In this episode of the Psychedelic Medicine Podcast, Nigel Denning, MA, MPsych, joins to discuss the reasons profound psychedelic experiences don't always lead to lasting change. Nigel is a Counselling Psychologist and Director of Integrative Psychology & Medicine, with nearly 40 years of experience working with psychedelic and non-ordinary states. He has trained with MAPS, and served as co-lead therapist on three psychedelic clinical trials.

In this conversation, Nigel emphasizes the importance of preparation, integration, and creating the conditions for new experiences to become part of everyday life for effective psychedelic therapy. He explains that psychedelic sessions can open a period of neuroplasticity, but that without adequate reinforcement, people may naturally return to familiar patterns and ways of understanding themselves. Nigel discusses his three-phase approach to integration, which begins with simply becoming familiar with the experience, moves into narrating and embodying it, and ultimately arrives at meaning-making. He also highlights the importance of somatic awareness, curiosity, breathwork, and stabilization in helping people integrate experiences without prematurely imposing intellectual interpretations. Throughout the conversation, Nigel cautions against rushing back into ordinary routines or repeatedly pursuing psychedelic states in search of a lasting transformation, instead encouraging people to give new experiences time and space to become woven into their everyday life.

 

In this episode, you'll hear:

  • The importance of preparation and setting realistic expectations before a psychedelic experience
  • Why curiosity is more useful than trying to control or rush to interpret what happens during a session
  • How somatic awareness and breathwork can help integrate psychedelic experiences
  • Why integration requires stabilization and creating space after an experience
  • Why it's never too late to begin integrating a psychedelic experience from the past
  • The risks of "state change chasing" and repeatedly pursuing psychedelic experiences instead of integrating them

 

Quotes:

"[Psychedelic therapy] is a very different way of intervening psychologically. You're really preparing someone to be curious about anything that arises so that they're not going in with expectations that this is going to be this incredibly wonderful experience that's just going to change their life—it might be a really awful experience—but that as long as you can make meaning of it as you're coming out of it, that's where the transformation comes." [5:28]

"We can't predict, we can't shape and control what happens in the session. Therefore, let's just get really curious. Let's learn how to breathe and slow down and relax ourselves into meeting anything that emerges." [6:11]

"The real meaning, the real return to subjectivity, is part of the integration process" [7:21]

"[Integration] is all about familiarizing the unfamiliar without racing into a top-down reduction of it into a thing that meant this." [21:45]

"It's amazing how stabilizing the breath can be. If you're in the depths of a psychedelic hell-world and you've got no perspective on anything, what you can still do is breathe. … that quality of centering in the breath creates then that capacity to at least remember you have a body." [27:21]

 

Links:

Nigel on LinkedIn

Integrative Psychology & Medicine website

Integrative Psychology & Medicine on Instagram

Psychedelic Medicine Association

Porangui


Exploring the frontier of mind and medicine, the Psychedelic Medicine Podcast with Dr. Lynn Marie Morski delves into the complex world of psychedelic substances and their potential to heal. Hosted by Lynn Marie Morski, a physician and attorney, this podcast navigates the intricate intersection of cutting-edge science, clinical practice, and evolving policy. Each episode brings a grounded, expert perspective to conversations about psilocybin, MDMA, ketamine, LSD, ayahuasca, ibogaine, and other compounds, moving beyond hype to examine the real-world implications of this therapeutic renaissance. Listeners will hear detailed discussions on the latest peer-reviewed research, practical insights from medical professionals integrating these approaches, and thoughtful analysis of the legal landscape shaping access. The dialogue is rooted in a commitment to safety, ethics, and evidence, offering a clear-eyed look at both the profound promise and the challenges inherent in psychedelic medicine. Whether you're a healthcare provider, a patient, a researcher, or simply intellectually curious, this podcast provides an essential, nuanced resource for understanding how these ancient and modern substances are reshaping perspectives on mental health, consciousness, and treatment. It’s a space for serious inquiry, where complex questions about healing, neuroscience, and society are met with informed, accessible conversation.
Author: Language: English Episodes: 50

Psychedelic Medicine Podcast with Dr. Lynn Marie Morski
Podcast Episodes
Who Is a Good Candidate for Ibogaine? with Fernando Rivas, MD [not-audio_url] [/not-audio_url]

Duration: 39:32
In this episode of the Psychedelic Medicine Podcast, Fernando Rivas, MD, joins to unpack the safety and screening considerations for ibogaine therapy. Dr. Rivas is an emergency physician with over 15 years of clinical ex…
Encore Episode: Psychedelics and Breathwork with Kyle Buller [not-audio_url] [/not-audio_url]

Duration: 43:58
This encore episode of the Psychdelic Medicine Podcast features a conversation with Kyle Buller on psychedelics and breathwork. Kyle is co-founder and host of the Psychedelics Today podcast and he has studied breathwork…
Psychedelics and Psychosis with Alexander Lebedev, MD, PhD [not-audio_url] [/not-audio_url]

Duration: 46:09
In this episode of the Psychedelic Medicine Podcast, Alexander Lebedev, MD, PhD joins to discuss psychedelic medicine and psychosis. Dr. Lebedev is a physician-scientist, medical AI engineer, and entrepreneur working at…
Psychedelics and GLP-1s with Arsalan Azam, MD [not-audio_url] [/not-audio_url]

Duration: 36:22
In this episode of the Psychedelic Medicine Podcast, Arsalan Azam, MD joins to unpack the intersection between psychedelics and GLP-1s. Dr. Azam, founder of Daydream MD, completed his residency in Emergency Medicine at t…
Psilocybin vs. Ketamine with Dori Lewis, LPC [not-audio_url] [/not-audio_url]

Duration: 43:11
In this episode of the Psychedelic Medicine Podcast, Dori Lewis, MA, MEd, LPC-S returns to discuss the differences between psilocybin and ketamine. Dori is the Clinical Director of Elemental Psychedelics and Owner/Operat…
Choosing the Right Ketamine Clinic for You with Katie Fassbinder, MD [not-audio_url] [/not-audio_url]

Duration: 50:19
In this episode of the Psychedelic Medicine Podcast, Katie Fassbinder, MD joins to explore how to choose the right ketamine clinic. Dr. Fassbinder is the Faculty Medical Lead for ketamine-assisted psychotherapy training…
The Future of Psychedelic Medicine with Ismail Lourido Ali, JD [not-audio_url] [/not-audio_url]

Duration: 52:24
In the 200th episode of the Psychedelic Medicine Podcast, Ismail Lourido Ali, JD joins to discuss the future of psychedelic medicine. Ismail serves as MAPS Co-Executive Director and has been actively participating in the…
Psychedelics and Neurodiversity with Dr. WaiFung Tsang, DClinPsy [not-audio_url] [/not-audio_url]

Duration: 43:31
In this episode, Dr. WaiFung Tsang, DClinPsy joins to discuss the intersection of psychedelics and neurodiversity. Dr. Tsang is a clinical research psychologist from Hong Kong, musician, and student of Shipibo curanderis…