Colostrum is Liquid Gold

Colostrum is Liquid Gold

Author: Balchem Animal Nutrition & Health January 23, 2024 Duration: 1:04:52

This episode is from a webinar presented by Dr. Sandra Godden from the University of Minnesota Department of Veterinary Population Medicine. To view the full webinar and access the slides referenced during this podcast, visit balchem.com/real science and scroll down to the webinar presented on November 8, 2023.

Dr. Godden begins with the reminder that despite decades of research and definite advances in colostrum management, there's still a lot to learn and research. Her goal is to give an update on new findings that can be utilized in your colostrum management program. (0:21)

Promoting calf health and growth is a balance between maximizing immunity and minimizing infectious disease challenges. Colostrum is one aspect of maximizing immunity and provides passive immunity in the form of immunoglobulins. It also contains bioactive compounds, immune factors, growth hormones, leukocytes, and nutrients. (1:09)

We can measure adequate transfer of passive immunity via serum immunoglobulin G levels, where anything greater than 10 grams per liter is a pass. Passive transfer of immunity is associated with reduced morbidity and mortality, especially in the first 2-3 months of life. Successful passive transfer has many other intermediate and long-term benefits, including improved growth rate and feed efficiency, leading to even longer-term benefits of decreased age at first calving and potentially improved milk production in the first and second lactation. (4:18)

When building a comprehensive colostrum management program, Dr. Godden distills it down to the five Qs: quality, quantity, quickness, squeaky clean, and quantifying. Starting with quantifying passive transfer, in a perfect world, we would have a quick, inexpensive, on-farm serum IgG test that could be run on whole blood. Unfortunately, that test does not exist. In research studies, we send serum samples off to reference labs to have serum IgG tested. On-farm, we use indirect tests such as serum Brix or serum total protein. Historically, the literature has said that a serum total protein of somewhere between 5.0 and 5.2 grams per deciliter most accurately predicts that IgG value of 10 grams per liter. If greater than 10 g/L IgG is a pass, is a higher concentration better? Yes. A good goal would be for 90% of the calves to have serum IgG higher than 10 g/L. More specifically, goals are around 40% of calves in the excellent zone of 25 or greater, roughly 30% of calves in the good zone of 18-25, and around 20% in the fair zone of 10-18. Dr. Godden references the corresponding Brix and total serum protein readings in her slides. (7:24)

Quality refers to the concentration of IgG in the colostrum, and experts have suggested that be at least 50 grams per liter or higher. This corresponds to a Brix reading of approximately 22% or higher. Several factors influencing colostrum quality are under our control, including the dry cow vaccination program, feeding a balanced dry cow ration, avoiding stressors during the dry period, avoiding excessively short dry periods, and milking cows out as soon as you can after calving. (16:18)

When it comes to quantity, a larger volume at first feeding will result in higher IgG concentrations in the calves. One study compared feeding two or four liters at first feeding with a second feeding of two liters at 12 hours. The higher volume first feeding showed better results. (29:23)

As for quickness, IgG absorption efficiency is optimal in the first couple of hours after birth but is then slowly reduced as gut closure occurs. Ideally, we want to feed the calf as soon as possible, hopefully within one to two hours of birth when possible. (30:35)

The last Q is squeaky clean or cleanliness, specifically the level of bacterial contamination in colostrum. Obviously, we don't want to feed colostrum that is laden with pathogens that can cause disease. However, high bacteria counts in colostrum have also been associated with reduced absorption of IgG. Dr. Godden details a number of critical control points that can be assessed if colostrum cleanliness is an issue of concern. (38:19)

Dr. Godden finishes the episode by taking questions from the webinar audience, ranging from average colostrum volume collected at first milking to what temperature colostrum should be frozen at to heat stress impacting quality and quantity of colostrum. (49:20)

Please subscribe and share with your industry friends to bring more people to join us around the Real Science Exchange virtual pub table.  

If you want one of our new Real Science Exchange t-shirts, screenshot your rating, review, or subscription, and email a picture to anh.marketing@balchem.com. Include your size and mailing address, and we’ll get a shirt in the mail to you.


Ever wonder what animal scientists talk about after the formal presentations are over and the notebooks are put away? Real Science Exchange-Dairy captures that exact spirit, moving beyond the lecture hall to explore the ideas shaping dairy and animal nutrition. Presented by Balchem Animal Nutrition & Health, this series feels more like a lively, insightful table conversation among colleagues than a staged interview. You’ll hear leading researchers and experts discuss pressing topics in the field, but in a relaxed, unfiltered way that reveals the person behind the data. The dialogue is driven by genuine curiosity and a shared passion for natural sciences, covering everything from emerging research to practical applications. Each episode is an exchange of perspectives, offering a range of new ideas that challenge conventional thinking. It’s a podcast for anyone interested in the real-world science that impacts animal health and productivity, delivered with the authenticity of a discussion among friends. Tune in for thoughtful, accessible conversations that connect complex concepts to the bigger picture of life and scientific discovery.
Author: Language: English Episodes: 205

Real Science Exchange-Dairy
Podcast Episodes
Legacy Series, Dr. Mike Hutjens, University of Illinois [not-audio_url] [/not-audio_url]

Duration: 1:11:15
Guests: Dr. Mike Hutjens, University of Illinois, Dr. Dave Fischer, University of Illinois, Dr. John Goeser, Rock River Lab and co-host, Dr. Jeff Elliott, BalchemThis week's episode is a favorite for many as part of our…
ADSA Research Winners Live at the Ice Cream Social [not-audio_url] [/not-audio_url]

Duration: 53:24
Today’s episode was recorded live at the American Dairy Science Association Annual Meeting in Kansas City, MO. Joining us are the ADSA research winners to discuss their projects. Lautaro Rostoll Cangiano joins us first.…
ADSA Balchem Research of Interest [not-audio_url] [/not-audio_url]

Duration: 1:48:41
Today’s episode is hosted live at the American Dairy Science Association Annual Meeting. It’s the second in our three-part series from the ADSA meetings.Abomasal infusion of branched-chain amino acids or branched-chain k…
ADSA Balchem Highlighted Research [not-audio_url] [/not-audio_url]

Duration: 1:20:44
Today’s episode is hosted live at the American Dairy Science Association Annual Meeting. It’s the first in our three-part series from the ADSA meetings where we are featuring graduate and post-doc students and their rese…
Surviving HPAI [not-audio_url] [/not-audio_url]

Duration: 57:51
Guests: Dr. Carol Cardona, University of Minnesota School of Veterinary Medicine; Dr. Julie Helm, Clemson Livestock Poultry Health; Myah Walker, Director of Quality and Training at Sparboe Farms; Co-host: Tom Powell, Dir…
Wonderful World of Fungal Toxins [not-audio_url] [/not-audio_url]

Duration: 1:22:28
Guests: Dr. Duarte Diaz, University of Arizona; Dr. Lon Whitlow, North Carolina State UniversityThere are a few things present in almost all environments and one of them is mold. Today on the Real Science Exchange we tal…
May Journal Club [not-audio_url] [/not-audio_url]

Duration: 53:08
Guests: Dr. Bill Weiss, The Ohio State University; Dr. Chanhee Lee, The Ohio State University; Haley Zynda, The Ohio State University Special Guest: Dr. Maurice Eastridge, The Ohio State University Today’s episode is an…