Peptides Beyond GLP-1 and How to Use Them Safely (feat. Dr. Aleksandra Gajer)

Peptides Beyond GLP-1 and How to Use Them Safely (feat. Dr. Aleksandra Gajer)

Author: Jenn Trepeck June 24, 2026 Duration: 43:22

Curious whether peptide therapy is the missing piece in your wellness routine, or just another overhyped trend? This episode breaks down what these powerful chemical messengers do in the body, from healing injuries to balancing brain chemistry, cellular energy and more, plus why sourcing and dosing make all the difference.

Host Jenn Trepeck sits down with Dr. Aleksandra Gajer to explore BPC 157, brain-supporting peptides, and mitochondrial function, while tackling how to use peptides safely, who should avoid them, and why they work best as a tool rather than a magic fix-all.

What You Will Learn in This Episode:

✅ How peptide therapy acts as a chemical messenger system that supports the body's own healing pathways rather than overriding them

✅ Why BPC 157 has become one of the most talked about peptides for tendon repair, gut healing, and recovery

✅ How neuroinflammation, not just neurotransmitter imbalance, may be driving anxiety, depression, and brain fog

✅ The role of mitochondrial function and insulin sensitivity in body composition, energy, and long-term metabolic health

The Salad With a Side of Fries podcast, hosted by Jenn Trepeck, explores real-life wellness and weight-loss topics, debunking myths, misinformation, and flawed science surrounding nutrition and the food industry. Let’s dive into wellness and weight loss for real life, including drinking, eating out, and skipping the grocery store.

TIMESTAMPS:

00:00 Dr. Aleksandra Gajer's path from emergency medicine to proactive, personalized healthcare

08:04 Defining peptides and their relationship to inflammation and healing

10:04 Exploring BPC 157 for tendon injury, gut healing, and tissue recovery

12:31 How peptides support autoimmune conditions by regulating immune balance

15:35 Brain peptides Selank and Semax and the truth behind the neuroinflammation link to anxiety

18:57 Understanding mitochondrial function, fatigue, and brain fog as cellular energy issues

20:35 MOTS-c, insulin sensitivity, and the connection to body composition

22:18 Why peptides work best as a tool, not a replacement for healthy habits

26:03 Safe peptide sourcing, endotoxins, and who should avoid peptide therapy

33:54 Hormone health, dosing strategy, and cycling peptides for sustainable results

KEY TAKEAWAYS:

💎 Peptide therapy works with the body's natural signaling system, supporting existing pathways instead of forcing a reaction the way many medications do

💎 BPC 157 shows strong potential for healing tendons and the gut, but lacks extensive human trials, so working with an informed provider matters

💎 Anxiety and depression may stem from neuroinflammation rather than a simple chemical imbalance, opening the door to new peptide-based approaches

💎 Safe peptide sourcing from a compounding pharmacy or tested lab is essential, since unregulated peptides can carry dangerous endotoxins

ABOUT THE GUEST:

Dr. Aleksandra Gajer, originally from Poland and raised in the United States, is a dedicated medical professional focused on advancing healthcare. She graduated with top honors from the University of Maryland School of Medicine and completed her residency in academic emergency medicine at The George Washington University.

Dr. Gajer’s special interests include sustainable weight loss, balanced hormone health, and longevity. She emphasizes the importance of lifestyle adjustments to optimize patients’ biology, promoting health, vitality, and long-term wellness. Inspired by her experiences in emergency medicine working with communities facing health challenges, she shifted her focus to proactive, comprehensive healthcare. Establishing The Gajer Practice allows her to offer personalized care and empower individuals to lead healthier lives by intervening before illness takes hold.

Driven by her lifelong goal, she is enthusiastic about sharing her expertise and dedication to contribute to a healthier future for her community.

RESOURCES:

Become a Happy Healthy Hub Member

Jenn’s Free Menu Plan

A Salad With a Side of Fries

A Salad With A Side Of Fries Merch

A Salad With a Side of Fries Instagram

About Uncomplicating Wellness

Text ‘Book’ to 833-801-0500

GUEST RESOURCES:

The Gajer Practice - Website

The Gajer Practice | Burke, VA - Facebook

The Gajer Practice - Dr. Aleksandra Gajer (@thegajerpractice) - Instagram

The Gajer Practice - YouTube

The Gajer Practice: Start Here

Free Introductory Call

The Gajer Practice Store

QUOTES:

06:38 “Western medicine is so incredible at certain things, but just doesn't cut it when it comes to chronic diseases, or even creating health for that matter.” - Jenn Trepeck

09:08 “Peptides as a therapeutic group have become popularized because Ozempic was a proof of concept that this can be used and it works.” - Dr. Aleksandra Gajer

14:09 “Some of these peptides can modulate or regulate and bring things back into balance, versus artificially pushing in one direction or the other.” - Jenn Trepeck

14:24 “Medications either force a pathway on or block that pathway, while peptides are like the first domino in a set of dominoes.” - Dr. Aleksandra Gajer

21:56 “A lot of people think peptides are a magic bullet, versus saying they're a tool.” - Jenn Trepeck

33:37 “Dosing matters, because at a certain dose, peptides are no longer acting as a peptide.” - Jenn Trepeck

SEO KEYWORDS:

Jenn Trepeck, Salad With A Side Of Fries, Nutrition Nugget, Health Coach, Weight Loss For Real Life, Peptide Therapy, Peptides, BPC 157, Body Composition, Inflammation, Injury Healing, Brain Health, Energy, Mood, Chemical Messengers, Tendon Injury, Gi Tract Healing, Autoimmune Conditions, Immune Regulation, Thymosin Alpha 1, Kpv, Neuroinflammation, Selank, Semax, Anxiety, Depression, Adhd, Serotonin Hypothesis, Mitochondrial Function, Mots-C, Insulin Sensitivity, Insulin Resistance, Metabolic Flexibility, Glp-1, Weight Loss, Body Recomposition, Hormone Health, Perimenopause, Menopause, Pcos, Compounding Pharmacy, Endotoxins, Peptide Sourcing, Longevity, Mitochondria, Growth Hormone Peptides, Peptides Beyond GLP-1, How To Use Peptides Safely


Ever feel like the world of nutrition and wellness is full of rules that just don't fit into your actual life? That's exactly where Salad With a Side of Fries Nutrition, Wellness & Weight Loss comes in. Hosted by coach Jenn Trepeck, this isn't about rigid meal plans or labeling foods as good or bad. Instead, it's a conversation about finding a practical, balanced approach that sticks. You'll hear honest discussions that cut through the noise of popular trends, offering tools for sustainable healthy eating that doesn't require perfection. Each episode feels like getting actionable advice from a knowledgeable friend who understands the real challenges of maintaining a healthy lifestyle while still enjoying the foods you love. The focus is on strategies that work long-term, moving beyond quick fixes to build a smarter, more flexible relationship with food and your overall well-being. Tune in for a refreshingly realistic take on weight loss and nutrition, where the goal is progress, not punishment, and where a side of fries can absolutely be part of the journey. This podcast provides the grounded perspective and straightforward wellness advice needed to finally feel unstuck and empowered in your choices.
Author: Language: English Episodes: 50

Salad With a Side of Fries  Nutrition, Wellness & Weight Loss
Podcast Episodes
Nutrition Nugget: Retatrutide [not-audio_url] [/not-audio_url]

Duration: 15:57
Nutrition Nugget! Bite-sized bonus episodes offer tips, tricks and approachable science. This week, Jenn is talking about Retatrutide, the third-generation injectable making waves as the most powerful weight-loss drug st…
The Next Frontier Files: Ask the Robot vs. the Tried & True (vol. 4) [not-audio_url] [/not-audio_url]

Duration: 23:50
A robot showed up in everyone's pocket, and it changed how guests answered one simple question for an entire year. This episode of The Next Frontier Files rewinds to year four, when artificial intelligence collided with…
Nutrition Nugget: Cortisol Face [not-audio_url] [/not-audio_url]

Duration: 7:33
Nutrition Nugget! Bite-sized bonus episodes offer tips, tricks and approachable science. This week, Jenn is talking about Cortisol Face. People online seem to have an opinion on that puffy, rounded, rosy-cheeked look, an…
The Next Frontier Files: New Doors, Your Choice (vol. 3) [not-audio_url] [/not-audio_url]

Duration: 24:54
Personalized wellness is reshaping the entire health conversation, and this new The Next Frontier Files episode proves the old rulebook is officially closed for good. From psychedelics and genetic testing to women's heal…
Nutrition Nugget: Kombucha [not-audio_url] [/not-audio_url]

Duration: 9:57
Nutrition Nugget! Bite-sized bonus episodes offer tips, tricks and approachable science. This week, Jenn is talking about Kombucha. Is this fizzy, tangy drink really the gut health hero everyone on social media claims it…
The Next Frontier Files: Precision and Permission (vol. 2) [not-audio_url] [/not-audio_url]

Duration: 27:00
Wellness trends move fast, yet volume two of The Next Frontier Files proves some predictions age well. Revisiting year two of the show, host Jenn Trepeck tracks the guests who forecasted metabolic health, gut health, and…
Nutrition Nugget: Frozen Vegetables [not-audio_url] [/not-audio_url]

Duration: 8:34
Nutrition Nugget! Bite-sized bonus episodes offer tips, tricks and approachable science. This week, Jenn is talking about frozen vegetables. With a summer Cyclospora scare putting salad greens on trial, is the humble fre…
The Next Frontier Files: The Frontier We Didn't Choose (vol. 1) [not-audio_url] [/not-audio_url]

Duration: 29:15
Seven years of Salad With a Side of Fries, seven frontiers, one wild ride through the evolution of wellness trends. Jenn Trepeck is pulling back the curtain on every guest’s “Next Frontier in Wellness” prediction this sh…
Nutrition Nugget: What's In Your Cup? [not-audio_url] [/not-audio_url]

Duration: 5:37
Nutrition Nugget! Bite-sized bonus episodes offer tips, tricks and approachable science. This week, Jenn is talking about what's in your cup, the mindset story that's been sitting with her all week. As Salad With a Side…
Pleasure is an Overlooked Key to Longevity (feat. Susan Bratton) [not-audio_url] [/not-audio_url]

Duration: 56:33
Sexual wellness isn't just about connection; it's a measurable driver of how long and how well you live. This episode reveals why intimacy and longevity are more linked than most people realize, and why so many couples n…