SNR #193: Lyle McDonald - Nutrient Partitioning & Fuel Utilization

SNR #193: Lyle McDonald - Nutrient Partitioning & Fuel Utilization

Author: Danny Lennon August 22, 2017 Duration: 1:21:42

Lyle McDonald

Lyle is the author of the Ketogenic Diet, the Rapid Fat Loss Handbook and the Guide to Flexible Dieting. He has been interested in all aspects of human performance physiology since becoming involved in competitive sports as a teenager. Pursuing a degree in Physiological Sciences from UCLA, he has spent almost 20 years of his life studying human physiology and the science, art and practice of human performance, muscle gain, fat loss and body recomposition.

Over the years, in addition to working with the general public, Lyle has worked primarily with endurance athletes, a few powerlifters, and some bodybuilders. Through his books, articles and his forum, he has helped thousands lose fat, gain muscle and get stronger or perform better.

In This Episode We Discuss:

Fundamentals of calorie partitioning
What actually influences the partitioning of fuel substrates and the fate of the calories we consume
Genetic differences in how much our body composition proportionally changes when either in a hyper- or hypo- caloric diet
Is there anything we can really do to modify this?
Insulin sensitivity in muscle and adipose tissue
Blood glucose responses to meals: For healthy individuals, how much does it matter?
Should you match carbohydrate intake to insulin sensitivity?


Sigma Nutrition Radio, hosted by nutrition scientist Danny Lennon, moves beyond the noise of diet trends and simplistic advice to explore the complex, fascinating world of human nutrition. This is a space for deep, evidence-based conversations that acknowledge the nuance and often contradictory nature of scientific research. Each episode delves into a specific topic within health, fitness, or dietetics, breaking down the underlying physiology, examining the latest studies, and discussing practical implications with expert guests. The goal isn't to hand out rigid meal plans but to cultivate the critical thinking skills necessary to navigate the ever-changing landscape of nutritional science. You'll hear detailed analyses of how research is conducted, thoughtful debates on contentious issues, and explorations of how evidence translates-or doesn't-into real-world recommendations for different individuals. Tuning into this podcast means committing to a more sophisticated understanding of how food, movement, and metabolism interact, leaving you better equipped to make informed decisions about your own health and skepticism towards the next big headline. Danny’s approach is both rigorous and accessible, making even the most detailed biochemical pathways relevant to everyday life. It’s for anyone who has ever wondered about the real story behind a nutrition claim and values substance over soundbites.
Author: Language: English Episodes: 620

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