991: Pair Programming with AI in Your Python Notebook, with Dr. Trevor Manz

991: Pair Programming with AI in Your Python Notebook, with Dr. Trevor Manz

Author: Jon Krohn May 12, 2026 Duration: 1:08:51
Dr. Trevor Manz of Marimo talks to Jon Krohn about Marimo Pair, an open-source agent skill that teaches coding agents like Claude Code how to drive a reactive Python notebook, reading cell state, running Python in the kernel, taking screenshots of cells, and iterating on data tasks the way agents iterate on traditional software. Trevor also unpacks recursive language models, his AnyWidget project that bridges Python and the web, and his journey from a Wisconsin small town and Harvard bioinformatics research to founding-engineer life at Marimo. Listen to the episode to hear why no matter where AI takes us, curiosity and going deep on a topic will always be valuable. Additional materials: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠www.superdatascience.com/991⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Interested in sponsoring a SuperDataScience Podcast episode? Email natalie@superdatascience.com for sponsorship information. In this episode you will learn: (07:04) What Marimo Pair is and how it teaches agents to use notebooks as a tool (13:03) How agent skills work as folders of markdown files (24:15) Trevor's day-to-day workflow combining Claude Code and Marimo Pair (31:51) Recursive language models and why they could be the future of agentic reasoning (57:33) Career advice on curiosity, going deep, and becoming a domain expert

Hosted by Dr. Jon Krohn, Super Data Science: ML & AI Podcast with Jon Krohn is a deep and accessible exploration of how artificial intelligence and machine learning are reshaping our world. Each episode features conversations with leading researchers, engineers, and entrepreneurs from both academia and industry, breaking down complex ideas into something tangible and relevant. You'll hear firsthand about emerging techniques, practical applications, and the evolving landscape of data-driven careers. The sheer volume of data in our world is growing at a staggering rate, and this podcast serves as a guide to understanding that expansion and finding your place within it. Rather than offering abstract theory, these discussions focus on real-world impact, from cutting-edge algorithms to the human stories behind major breakthroughs. Tune in for a thoughtful, nuanced look at the tools and trends that are defining the future, all through the lens of experts who are building that future every day. Whether you're actively working in the field or simply curious about the forces driving technological change, this podcast provides a consistent source of insight and inspiration, demystifying the science that is quietly transforming every aspect of our lives.
Author: Language: English Episodes: 100

Super Data Science: ML & AI Podcast with Jon Krohn
Podcast Episodes
937: How to Design AI-First Products, with Marc Dupuis [not-audio_url] [/not-audio_url]

Duration: 59:32
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936: LLMs Are Delighted to Help Phishing Scams [not-audio_url] [/not-audio_url]

Duration: 5:07
How much power – and risk – do we carry around with us in our pockets? A Reuters investigation about how easily LLMs can be utilized for online phishing scams is the subject of this week’s Five-Minute Friday with Jon Kro…
934: Is AI Replacing Junior Workers? [not-audio_url] [/not-audio_url]

Duration: 6:55
With the number of jobs dramatically slowing in the last year, many question if this decline is down to companies turning to AI for completing entry-level tasks in particular. Research published earlier this month by Yal…
932: Should You Build or Buy Your AI Solution? With Larissa Schneider [not-audio_url] [/not-audio_url]

Duration: 29:10
Larissa Schneider speaks to Jon Krohn in this Feature Friday about finding the right time to invest in AI solutions, and when it’s better to build them yourself. She discusses her work leading global strategy and operati…
930: In Case You Missed It in September 2025 [not-audio_url] [/not-audio_url]

Duration: 37:25
Jon Krohn’s highlights from this month of interviews focus on ways to future-proof your career, looking at the hardware that will get you the most mileage, the emerging roles that are well worth a look, and the developme…
928: The “Lethal Trifecta”: Can AI Agents Ever Be Safe? [not-audio_url] [/not-audio_url]

Duration: 5:55
Prompt injections, malicious code, and AI agents: In this week’s Five-Minute Friday, Jon Krohn looks into the current security weaknesses found in AI systems. A structural vulnerability that The Economist dubs a “lethal…