Parkinson's Disease & Gastroparesis: The Gut-Brain Connection Explained

Parkinson's Disease & Gastroparesis: The Gut-Brain Connection Explained

Author: G-PACT non profit August 12, 2026 Duration: 43:45

Could Parkinson's disease begin in the gut? Emerging research suggests the connection between the gut and brain may be much stronger than we once believed.In this episode, Sam talks with Dr. Trisha Pasricha to explore the relationship between Parkinson's disease, gastroparesis, constipation, and other gastrointestinal disorders. Together, they discuss how digestive symptoms often appear years before neurological symptoms, why dopamine plays an important role in both the brain and the digestive tract, and what researchers are learning about the gut-brain axis.Dr. Pasricha explains why many people living with Parkinson's struggle with delayed gastric emptying, constipation, nausea, and other GI symptoms that can significantly impact quality of life. She also shares why treating digestive symptoms can be especially challenging, how specialists approach care, and what promising research may mean for future treatments.The conversation also dives into the importance of multidisciplinary care, the benefits of pelvic floor therapy, patient advocacy, and why understanding the whole body is essential when managing chronic illness.


Hosted by two people navigating life with gastroparesis, Surviving out of Spite is a raw and real conversation from the G-PACT non-profit. This isn't a clinical lecture; it's the sound of two friends unpacking the daily reality of a chronic condition, finding humor in the absurd moments and solidarity in the shared struggles. You'll hear candid personal stories that range from frustrating to triumphant, alongside practical tips forged from lived experience. The dialogue covers everything from managing health and relationships to simply preserving your identity beyond a diagnosis. Tuning into this podcast feels like pulling up a chair to a kitchen table conversation where no topic is off-limits and laughter is considered essential medicine. It builds a community through audio, reminding anyone facing a similar journey that they are understood. Each episode explores the complex patient experience with honesty, aiming to inform, connect, and affirm that navigating life with gastroparesis is a story of resilience, often fueled by a bit of defiant spirit.
Author: Language: en-us Episodes: 50

Surviving out of Spite
Podcast Episodes
Episode 29: Hope in a Broken Digestive System [not-audio_url] [/not-audio_url]

Duration: 51:07
Gastroparesis isn’t just about digestion — it’s about identity, grief, resilience, and learning how to fight for yourself. In this episode, Sam and Dr. Eva Alsheik unpack the science behind gastroparesis, the mental heal…
Episode 28: When Voices Become a Movement [not-audio_url] [/not-audio_url]

Duration: 12:10
In this final episode of the year, Sam pulls back the curtain on what it really takes to grow a chronic illness community. From the early days of G-PACT to the powerful network it’s become today, she reflects on the wins…
Episode 27: The Missing Piece in GI Treatment [not-audio_url] [/not-audio_url]

Duration: 42:16
In this week's episode, Megan Riehl joins the show to break down the brain–gut connection and why it’s a physiological process, not a dismissal. We explore how stress and nervous system dysregulation directly affect GI f…
Episode 26: When Fitness isn't Built for Us [not-audio_url] [/not-audio_url]

Duration: 51:31
In this episode, Sam sits down with Kate Bochnewetch, a physical therapist and running/strength coach, for a conversation about living, moving and thriving with chronic illness. Drawing from her own journey with hEDS syn…
Episode 25: Empowering Patients through Nutrition [not-audio_url] [/not-audio_url]

Duration: 48:23
In this episode, we’re joined by Jennifer Akimoto. She’s a registered dietitian with 20 years of clinical nutrition experience, and today, we are talking about the world of blended tube feeding. Inspired by a patient’s d…