Bills vs Patriots Week Five Preview & Bold Predictions

Bills vs Patriots Week Five Preview & Bold Predictions

Author: Blue Wire October 3, 2025 Duration: 45:01

On this episode of Talking Buffalo, Patrick Moran previews the exciting Sunday night football Week five matchup between the Buffalo Bills and New England Patriots at Highmark Stadium in addition to his three keys to a Bills victory, five game bold predictions and a stab at nailing the final score.

Buffalo is the last remaining undefeated team in the AFC and just one of two left in the league. They should expect a stiff test from a 2-2 Patriots team with plenty to prove and is excited for the opportunity to come to Orchard Park and knock off the powerhouse Bills. They better because if the Bills win this game the AFC east will be all but locked up before we hit Columbus Day.

Patrick takes a look at the strengths and weakness of both teams coming in and a potential good vs good matchup as the Bills running game is the best in football while New England's one of the best at stopping in. He then outlines three big keys to a Bills victory including being able to shut down New England's reigning AFC Special Teams Player of the Week, who decimated Carolina last week on punt returns.

As always, Patrick offers five bold predictions for the game and one of them has Ty Johnson, who's done basically nothing for the Buffalo offense this season finding his way to the end. Before leaving Patrick gives his final score prediction. Will the Bills cover the 7.5 spread? That and plenty more.

The Talking Buffalo online merch store is now live! You can purchase t shirts, hoodies, zip ups, crewnecks and polos in a couple of different styles and colors. Visit our online page for pricing and options and while there, check out Buf on Weck for tons of cool gear!

Major props to Talking Buffalo sponsor, Sonny Red’s at 1841 Abbott Road in Lackawanna, just minutes from Highmark Stadium. We consider them THE most underrated spot for wings, pizza and other great food in Western New York plus it’s a great place to drink and have a great time. Also big thanks to Imperial Pizza and their two locations (1035 Abbott Road and 1655 Main Street), home of not only great pizza and tons of other delicious eats but also the best everyday lunch special in town.

♦♦♦♦♦

Follow Patrick Moran/Talking Buffalo Podcast 

Substack: Patrick Moran’s Substack

Twitter: @PatrickMoranTB

Blue Sky: @PatrickMoranTB.bsky.social

Instagram: @PatrickMoranTB

Facebook: Talking Buffalo Podcast 


Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.


There's a particular kind of passion that comes from following Buffalo sports, a mix of unwavering hope and hardened realism that Talking Buffalo captures perfectly. Hosted by Buffalo-born Patrick Moran, this Blue Wire podcast dives deep into the heart of the city's teams, with a primary focus on the emotional rollercoasters provided by the Bills and Sabres. Patrick doesn't just report on games; he lives them, offering a perspective that can swing from critical skepticism to full-blown optimism in a single conversation. That authentic, sometimes self-deprecating fan voice is exactly what drives each episode. The show regularly features interviews with guests from across the sports world, media, and even pop culture, providing unique angles and insider insights you won't find elsewhere. It’s this blend of local passion, candid analysis, and diverse conversations that gives the podcast its character. You'll hear the highs, the lows, and all the gritty commentary in between, all filtered through the experience of someone who truly understands what it means to invest in these teams. For anyone who bleeds blue and red or simply appreciates the complex narrative of a sports city, Talking Buffalo feels like a conversation with a knowledgeable, and admittedly opinionated, friend.
Author: Language: English Episodes: 1000

Talking Buffalo
Podcast Episodes
Bills vs Eagles Preview, Predictions [not-audio_url] [/not-audio_url]

Duration: 39:38
On this Black Friday episode of Talking Buffalo, Patrick Moran is joined by Anthony Marino from Buffalo Rumblings for a second consecutive day, this time to preview the Buffalo Bills vs Philadelphia Eagles showdown on Su…
A Talking Buffalo Thanksgiving [not-audio_url] [/not-audio_url]

Duration: 32:10
On this Thanksgiving day episode of Talking Buffalo, Patrick Moran is joined by friend and recurring guest Anthony Marino from Buffalo Rumblings to discuss the Buffalo Bills, more specifically a dive into their offense a…
Bills Film Study & PFF Grades Analysis, Week 11 [not-audio_url] [/not-audio_url]

Duration: 41:34
On this episode of Talking Buffalo, Patrick Moran has his weekly thoughts and observations on the Buffalo Bills after watching the coaches All-22 film and analyzing the PFF grades of a dominating 32-6 victory over the Ne…
Let's Go, Buffalo? [not-audio_url] [/not-audio_url]

Duration: 1:29:57
On this episode of Talking Buffalo, Patrick Moran is joined by writer and sports media personality Joe Yerdon to discuss a rare double win for Buffalo on Sunday as both the Bills and Sabres got much needed victories. Is…
Reaction: Bills Offense Finally Explodes on Jets [not-audio_url] [/not-audio_url]

Duration: 1:17:41
On this episode of Talking Buffalo, Patrick Moran is joined by longtime friend and recurring guest Tone Pucks for his weekly visit to discuss the Buffalo Bills offense finally having the explosion we've been waiting on i…
Bills vs Jets Keys To Game, Predictions & Reading Your Comments [not-audio_url] [/not-audio_url]

Duration: 40:36
On this rare weekend episode of Talking Buffalo, Patrick Moran talks about Buffalo's critical showdown Sunday with the New York Jets, offers his three biggest Bills key to the game and a prediction in addition to reading…
Chad DeDominicis Talks Sabres & Bills (Live From Imperial) [not-audio_url] [/not-audio_url]

Duration: 1:11:14
On this episode of Talking Buffalo, it’s another installment of the “Live from Imperial” series as Patrick Moran is joined by Expected Buffalo creator and Buffalo Sabres blogger Chad DeDominicis to discuss turbulent time…
Ken Dorsey's Firing Is Deserved But Doesn't Solve Biggest Issue [not-audio_url] [/not-audio_url]

Duration: 50:57
On this episode of Talking Buffalo, Patrick Moran discusses the Buffalo Bills firing of offensive coordinator Ken Dorsey on Tuesday morning--how much of it is deserves and how much of it is Dorsey being the scapegoat for…
Live Reaction: The 2023 Buffalo Bills Are Toast [not-audio_url] [/not-audio_url]

Duration: 40:26
On this episode of Talking Buffalo, Patrick Moran recorded (also lived streamed) literally just minutes after the Buffalo Bills blew a late lead, and very likely their season by losing at home in prime time to the Denver…
Are The Bills One of Seven Best in The AFC ? [not-audio_url] [/not-audio_url]

Duration: 1:28:13
On this episode of Talking Buffalo, Patrick Moran is joined by longtime friend and recurring guest Tone Pucks for his weekly visit to discuss the Buffalo Bills must-win game against Denver on Monday night in addition to…