#511 Alzheimer's Disease: Updates in Diagnosis and Treatment

#511 Alzheimer's Disease: Updates in Diagnosis and Treatment

Author: The Curbsiders Internal Medicine Podcast January 12, 2026 Duration: 1:16:48

Blood-based Biomarkers, Anti-Amyloid Therapies and Beyond

From blood-based biomarkers to anti-amyloid treatments, join us as we explore the latest in Alzheimer’s disease diagnosis and treatment with Dr. Halima Amjad. This episode will equip you to guide your patients about the latest Alzheimer’s diagnostics as well as eligibility, risks and monitoring for anti-amyloid therapies.

Claim CME for this episode at curbsiders.vcuhealth.org!

Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CME

Show Segments

  • Intro
  • Case
  • Cognitive and functional history reminders
  • Diagnosing Alzheimer’s Disease
  • Blood-based biomarkers
  • Anti-amyloid therapy indications, eligibility and contraindications
  • Patient counseling and treatment decisions
  • ARIA
  • Key takeaways
  • Outro

Credits

  • Written and Produced by: Natalie Barrett DO, Rachel K Miller MD
  • Show notes, cover art and infographic: Natalie Barrett DO, Rachel K Miller MD, Leah Witt MD
  • Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP   
  • Reviewer: Sai S Achi MD, MBA,FACP
  • Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
  • Technical Production: PodPaste
  • Guest: Halima Amjad, MD


Disclosures

Dr. Amjad reports financial relationships with Centene (Advisor) and Craniometrix (Advisor). Relationships have not ended. The Curbsiders report no relevant financial disclosures. 

The production of this episode was supported by the Penn Geriatrics AGE-SMART Geriatric Workforce Enhancement Grant. This podcast content is solely the responsibility of the authors and does not necessarily represent the official views of the Health Resources and Services Administration or the U.S. Department of Health and Human Services. 


Sponsor:
Babbel 

Right now get up to 55% off your Babbel subscription at Babbel.com/CURB.

Sponsor: Quince

Go to Quince.com/curb for free shipping on your order and 365-day returns. Now available in Canada, too.

Sponsor:
Sanford Guide

Search for Sanford Guide in the app stores. And, Curbsiders listeners can get 20% off the already very moderately priced yearly subscriptions directly at sanfordguide.com. Go to sanfordguide.com and use the code, CURB at checkout.


Tune in to The Curbsiders Internal Medicine Podcast for a direct line to practical clinical knowledge and the ever-evolving art of patient care. This isn't a dry lecture series; it's a dynamic conversation among practicing physicians who break down complex topics into actionable insights you can use. Each episode delves into the nuances of internal medicine, from managing common chronic conditions to interpreting the latest guidelines and navigating diagnostic dilemmas. You'll hear honest discussions about challenges at the bedside, evidence-based debates, and expert interviews that go beyond textbook summaries to reveal how medicine works in the real world. The podcast serves as both a continuing education resource and a professional companion, offering thoughtful analysis and clinical pearls that resonate whether you're a seasoned hospitalist, a resident in training, or a primary care provider. The focus is consistently on deepening understanding and improving daily practice, making the rounds or the clinic day feel a little less daunting and a lot more informed. Listen for a blend of curiosity, camaraderie, and a genuine commitment to mastering the craft of medicine, all delivered through engaging dialogue that feels like consulting with a trusted colleague.
Author: Language: English Episodes: 100

The Curbsiders Internal Medicine Podcast
Podcast Episodes
UNLOCKED #43 Exclusive! HFrEF (TFTC audio) [not-audio_url] [/not-audio_url]

Duration: 30:37
Join us at patreon.com/curbsiders today and save 20% on NEW Annual Memberships with promo code: UNLOCKED. *This offer expires at 3am EST on May 15, 2025. Matt and Paul recap top pearls from a recent episode on heart fail…
#482 Recap from SHM #Converge25 [not-audio_url] [/not-audio_url]

Duration: 1:29:15
Highlights and Pearls from SHM’s Annual MeetingWe recap the top pearls for the hospitalist from #SHM #Converge25 hitting updates in GI, stroke, anticoagulation, perioperative medicine, artificial intelligence, and more.…
#481 Prediabetes and Diabetes Prevention with Dr. Scott Isaacs [not-audio_url] [/not-audio_url]

Duration: 1:33:25
Conquer prediabetes and diabetes prevention! We’re joined by Dr. Scott Isaacs, who provides essential pearls on navigating screening tests for diabetes and prediabetes, identifying atypical cases of prediabetes, and indi…
#480 Hypermobility with Dr. Linda Bluestein [not-audio_url] [/not-audio_url]

Duration: 1:24:11
Don’t bend the knee to hypermobility! Learn how to evaluate patients for possible joint hypermobility, what associated conditions to be mindful of, and where to start with management. We’re joined by Dr. Linda Bluestein,…
#479 Managing Treatment-Resistant Depression featuring Dr. Jessi Gold [not-audio_url] [/not-audio_url]

Duration: 1:34:04
Lead the way in depression management! We’re joined by Dr. Jessi Gold, a psychiatrist and mental health advocate, who provides essential pearls on ways to recognize the multifaceted nature of depression and similarly pre…
#478 Dementia 2.0 with Anna Chodos [not-audio_url] [/not-audio_url]

Duration: 1:30:06
Updates in classification, evaluation, and treatmentBecome dexterous with dementia management! We’re talking with Dr. Anna Chodos about cognitive domains, diagnostic criteria, patient and caregiver resources, new antibod…