David Pfau: Manifold Factorization and AI for Science

David Pfau: Manifold Factorization and AI for Science

Author: Daniel Bashir July 11, 2024 Duration: 2:00:52

Episode 130

I spoke with David Pfau about:

* Spectral learning and ML

* Learning to disentangle manifolds and (projective) representation theory

* Deep learning for computational quantum mechanics

* Picking and pursuing research problems and directions

David’s work is really (times k for some very large value of k) interesting—I’ve been inspired to descend a number of rabbit holes because of it.

(if you listen to this episode, you might become as cool as this guy)

While I’m at it — I’m still hovering around 40 ratings on Apple Podcasts. It’d mean a lot if you’d consider helping me bump that up!

Enjoy—and let me know what you think!

David is a staff research scientist at Google DeepMind. He is also a visiting professor at Imperial College London in the Department of Physics, where he supervises work on applications of deep learning to computational quantum mechanics. His research interests span artificial intelligence, machine learning and scientific computing.

Find me on Twitter for updates on new episodes, and reach me at editor@thegradient.pub for feedback, ideas, guest suggestions.

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Outline:

* (00:00) Intro

* (00:52) David Pfau the “critic”

* (02:05) Scientific applications of deep learning — David’s interests

* (04:57) Brain / neural network analogies

* (09:40) Modern ML systems and theories of the brain

* (14:19) Desirable properties of theories

* (18:07) Spectral Inference Networks

* (19:15) Connections to FermiNet / computational physics, a series of papers

* (33:52) Deep slow feature analysis — interpretability and findings on eigenfunctions

* (39:07) Following up on eigenfunctions (there are indeed only so many hours in a day; I have been asking the Substack people if they can ship 40-hour days, but I don’t think they’ve gotten to it yet)

* (42:17) Power iteration and intuitions

* (45:23) Projective representation theory

* (46:00) ???

* (46:54) Geomancer and learning to decompose a manifold from data

* (47:45) we consider the question of whether you will spend 90 more minutes of this podcast episode (there are not 90 more minutes left in this podcast episode, but there could have been)

* (1:08:47) Learning embeddings

* (1:11:12) The “unexpected emergent property” of Geomancer

* (1:14:43) Learned embeddings and disentangling and preservation of topology

* n/b I still haven’t managed to do this in colab because I keep crashing my instance when I use s3o4d :(

* (1:21:07) What’s missing from the ~ current (deep learning) paradigm ~

* (1:29:04) LLMs as swiss-army knives

* (1:32:05) RL and human learning — TD learning in the brain

* (1:37:43) Models that cover the Pareto Front (image below)

* (1:46:54) AI accelerators and doubling down on transformers

* (1:48:27) On Slow Research — chasing big questions and what makes problems attractive

* (1:53:50) Future work on Geomancer

* (1:55:35) Finding balance in pursuing interesting and lucrative work

* (2:00:40) Outro

Links:

* Papers

* Natural Quantum Monte Carlo Computation of Excited States (2023)

* Making sense of raw input (2021)

* Integrable Nonparametric Flows (2020)

* Disentangling by Subspace Diffusion (2020)

* Ab initio solution of the many-electron Schrödinger equation with deep neural networks (2020)

* Spectral Inference Networks (2018)

* Connecting GANs and Actor-Critic Methods (2016)

* Learning Structure in Time Series for Neuroscience and Beyond (2015, dissertation)

* Robust learning of low-dimensional dynamics from large neural ensembles (2013)

* Probabilistic Deterministic Infinite Automata (2010)

* Other

* On Slow Research

* “I just want to put this out here so that no one ever says ‘we can just get around the data limitations of LLMs with self-play’ ever again.”



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Hosted by Daniel Bashir, The Gradient: Perspectives on AI moves beyond surface-level headlines to explore the intricate machinery and human ideas shaping artificial intelligence. Each episode is built on a foundation of deep research, leading to conversations that are both technically substantive and broadly accessible. You'll hear from researchers, engineers, and philosophers who are actively building and critiquing our technological future, discussing not just how AI systems work, but the larger implications of their integration into society. This isn't about speculative hype; it's a grounded examination of real progress, persistent challenges, and ethical considerations from those on the front lines. The discussions peel back layers on topics like model architecture, policy, and the fundamental science behind the algorithms becoming part of our daily lives. For anyone curious about the substance behind the buzz-whether you have a technical background or are simply keen to understand a defining technology of our age-this podcast offers a crucial and thoughtful resource. Tune in for a consistently detailed and nuanced take that treats artificial intelligence with the complexity it deserves.
Author: Language: English Episodes: 100

The Gradient: Perspectives on AI
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