A New Approach to OCD: Internal Family Systems w/ Melissa Mose

A New Approach to OCD: Internal Family Systems w/ Melissa Mose

Author: Robert Duff, Ph.D. November 10, 2025 Duration: 1:17:26

In this deeply informative episode, I'm joined by licensed marriage and family therapist Melissa Mose, LMFT, who brings 30 years of clinical experience to the table and a unique approach to treating OCD by integrating Internal Family Systems (IFS) with traditional methods like Exposure and Response Prevention (ERP).

Melissa shares how a personal experience—her daughter's sudden-onset OCD—propelled her into the world of OCD treatment and changed the direction of her career. We talk through how OCD manifests, why traditional ERP can be both life-changing and difficult for people, and how IFS can offer a more compassionate, effective way to approach healing by helping clients access their internal "Self."

We also discuss Melissa's new book for clinicians, her training work, and the upcoming OCD SoCal Conference happening online on November 15–16, 2025.


🧠 What We Discuss in This Episode:

  • Melissa's unexpected path from literature and mythology to psychotherapy

  • The sudden-onset OCD experience with her daughter that changed everything

  • What OCD really is – beyond stereotypes – and why it's often misunderstood

  • Core concepts of ERP (Exposure and Response Prevention)

  • How Internal Family Systems (IFS) works and its 8 C's of Self-energy

  • Why combining IFS and ERP may provide better outcomes for some people

  • "Self-led ERP" – Melissa's integrative model for treating OCD

  • Real-life examples of recovery using this compassionate framework

  • The importance of identifying OCD early, especially in kids

  • Training efforts to help clinicians recognize and effectively treat OCD

  • Hope for those who feel "too far gone"


⏱️ Episode Chapters & Timestamps:

00:00 – Intro to Melissa Mose and IFS for OCD
03:00 – Melissa's background and shift from English literature to psychology
08:00 – Early career in teen and family systems therapy
11:00 – Her daughter's sudden-onset OCD and the diagnosis of PANDAS
14:30 – Navigating confusion, misdiagnosis, and treatment discovery
18:00 – What OCD actually is: the obsession-compulsion cycle
22:00 – How compulsions generalize and worsen OCD
24:30 – Introduction to ERP and how it works
29:00 – What is Internal Family Systems (IFS)?
34:00 – Comparing IFS to ACT and other models
42:00 – Mapping OCD symptoms to internal "parts" using IFS
48:00 – A self-led approach to ERP: empowering the Self
50:30 – Client success stories and examples
55:00 – The rise of IFS in the OCD world
58:00 – Is IFS evidence-based for OCD?
01:00:00 – Melissa's "Self-led ERP" model explained
01:02:00 – Workbook and practical tools coming soon
01:04:00 – How to get started with IFS
01:08:00 – Inside Out, visualization, and self-awareness
01:10:00 – Making IFS for OCD more accessible worldwide
01:12:00 – Final thoughts: hope and next steps for those struggling


📚 Resources & Links from the Episode

🔹 Melissa Mose's Website
https://www.melissamosemft.com/

🔹 IFS for OCD Resources and Courses
https://www.ifsforocd.com/blog

🔹 Melissa's Book:
Internal Family Systems Therapy for OCD: A Clinician's Guide
📘 On Amazon: Buy here
📘 On Routledge: https://www.routledge.com/Internal-Family-Systems-Therapy-for-OCD-A-Clinicians-Guide/Mose/p/book/9781032583730

🔹 OCD SoCal 2025 Online Conference (November 15–16, 2025)
🌐 Full Program Info: https://ocdsocal.org/conference/
🎟️ Register Here: https://www.eventbrite.com/e/2025-online-ocd-conference-a-global-event-tickets-1531193865069?aff=oddtdtcreator

🎧 Stay Connected with Me


Robert Duff, Ph.D., is a neuropsychologist who finds most self-help advice too sanitized to be useful. On The Hardcore Self-Help Podcast with Duff the Psych, he cuts through the fluff with a direct, science-backed approach. Each episode is built on the premise that real improvement requires honest, sometimes uncomfortable conversations. Duff brings his background in neuroscience and clinical psychology to interviews with a wide range of fascinating guests, dissecting topics from mental health struggles and relationship dynamics to the latest brain research. Listeners consistently note his skill at asking pointed questions that get to the heart of an issue, then translating complex psychological concepts into language anyone can apply. This isn't about quick fixes or vague positivity; it's a practical, evidence-based look at how our minds work and how we can work with them better. The tone is conversational and grounded, like getting actionable advice from a knowledgeable friend who isn't afraid to tell it like it is. Whether exploring anxiety, habits, or the science of motivation, this podcast delivers substance without the jargon, making professional insights accessible for everyday life. You'll find the discussions are both deeply informative and surprisingly relatable, a combination that has built a dedicated audience for Duff's unique perspective.
Author: Language: English Episodes: 100

The Hardcore Self-Help Podcast with Duff the Psych
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