#227 The Gut-Longevity Connection: How Pendulum’s Live Akkermansia Is Revolutionizing Metabolic Health - Dr. Colleen Cutcliffe

#227 The Gut-Longevity Connection: How Pendulum’s Live Akkermansia Is Revolutionizing Metabolic Health - Dr. Colleen Cutcliffe

Author: Claudia von Boeselager November 12, 2025 Duration: 48:02
When it comes to longevity, your gut might hold the master key. In this fascinating episode, Colleen Cutcliffe, PhD, CEO and co-founder of Pendulum Therapeutics, reveals how a single gut bacteriu, Akkermansia muciniphila - is transforming the future of metabolic and hormonal health. From her daughter’s early health challenges to pioneering live Akkermansia in supplement form, Colleen shares her journey from biotech to natural therapeutics. Discover how the microbiome impacts metabolism, energy, brain function, menopause, and even GLP-1 hormone production—the same pathway drugs like Ozempic mimic. We explore: - Why 88% of Americans are metabolically unhealthy - The gut’s role as the root system of longevity - How Akkermansia acts as “the glue” for gut lining integrity - The connection between gut bacteria and women’s hormones - Breakthroughs in microbiome-based therapies and “bugs as drugs” Whether you’re curious about reversing metabolic dysfunction or optimizing your healthspan naturally, this episode is your deep dive into the science and soul of gut health. This episode is brought to you by Pendulum - get 20% off your first membership order at pendulumlife.com/CLAUDIA20, your discount applies automatically.

Hosted by Claudia von Boeselager, The Longevity & Lifestyle Podcast moves beyond simple health tips to explore a more integrated vision of well-being. Each conversation focuses on practical, often overlooked strategies drawn from pioneering experts across various fields. The aim is to provide listeners with tangible tools and perspectives that contribute to a longer, more vibrant life, framing personal health as the foundation for greater impact. This isn't just about adding years; it's about enriching the quality of every day, examining how daily choices in fitness, mindset, and self-improvement collectively shape our potential. Claudia's approach is grounded in empowerment, offering a blend of alternative and mainstream wisdom to help you craft a resilient and optimized lifestyle. You'll hear detailed discussions on applying these principles in realistic ways, breaking down complex ideas into actionable steps. The podcast serves as a dedicated space for anyone looking to thoughtfully upgrade their habits and outlook, driven by a mission to make holistic health knowledge accessible and actionable. Tune in for a deep, nuanced exploration of what it truly means to live at your best, discovering how refined daily practices can extend your healthspan and amplify your capacity to contribute positively to the world around you.
Author: Language: English Episodes: 100

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