What if sweetness itself isn’t the real problem?
In this episode, Claudia welcomes back Sakiko Reuterskiöld, founder and CEO of NOMOSU, to explore the science of sugar, fructose, fiber, cravings, sweeteners, the microbiome, and metabolic health. Sakiko explains why many people may be blaming the wrong thing when it comes to blood sugar, weight gain, and long-term metabolic dysfunction and why the bigger issue may be excess sugar, especially liquid fructose, low fiber intake, and the structure of modern foods.
They discuss the difference between sweet taste and metabolic harm, why liquid fructose may be especially damaging over time, how fiber supports satiety, insulin sensitivity, and gut health, and what the science really says about stevia, erythritol, cacao, and so-called “healthy” sugars. This episode is especially relevant for anyone who wants better energy, fewer cravings, improved blood sugar control, and a smarter, more science-backed relationship with sweetness.
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Timestamps
00:00 Intro and Sakiko’s mission to rethink sweetness through metabolic and gut health
02:08 Why sweetness itself may not be the real problem
03:57 Glucose vs fructose — and why fructose can be more harmful over time
05:32 Why liquid fructose is especially damaging for metabolic health
06:44 Sakiko’s personal story with sugar, cravings, and energy
08:39 Dates, honey, maple syrup, and agave — are they really healthier?
12:18 The biggest misinformation around sweeteners and health headlines
13:55 Stevia, monk fruit, erythritol, xylitol, allulose, and sweet proteins explained
16:19 Erythritol controversy — what people may be misunderstanding
19:38 Stevia deep dive — insulin sensitivity, cravings, and misconceptions
24:17 Have we lost the ability to taste real sweetness?
26:57 How to reset your palate and reduce sugar cravings
27:45 Why fiber is foundational for metabolic health and healthspan
29:49 Fiber, satiety hormones, GLP-1, and fullness signals
30:46 Easy fiber upgrades and practical daily strategies
31:12 Fiber, cravings, short-chain fatty acids, and the microbiome
32:28 Inulin, fructose handling, and the gut-liver connection
34:00 Fiber and cardiovascular health, LDL, ApoB, and inflammation
44:33 Where to find Sakiko and learn more about NOMOSU
Learn more about Peptides for High Performance; https://peptidefoundation.lumaralearn.com/
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