Sam Altman on Where AI Models Go Next, with Nicholas Thompson

Sam Altman on Where AI Models Go Next, with Nicholas Thompson

Author: Atlantic Re:think April 29, 2026 Duration: 53:15
OpenAI’s Sam Altman sits for an interview with Nicholas Thompson, CEO of The Atlantic, to discuss AI’s trustworthiness, its dangers, and its impact on young people. Altman also discusses his company’s pledge to “stop competing and start assisting” rival projects that approach AGI, and why he thinks we’re not there yet. In a thorough and wide-ranging conversation, Altman opens up about where he thinks AI will go next and the mysteries that he still can’t solve. Recorded at OpenAI’s offices in San Francisco. (00:00) Introduction (02:33) Is our understanding of AI keeping pace with its growth in power? (05:10) Is chain-of-thought the key to trusting a model? (11:07) Open source AI, cybersecurity, and "infected" agents (16:26) Have we hit recursive self-improvement? (19:18) What does AI do on Sam Altman's computer? (21:15) Why hasn't AI made an impact in business yet? (24:04) Will AI make the wealth gap worse? (27:01) Why do young people hate AI?  (30:23) The challenges of AI sycophancy  (33:36) Do you regret making AI so human-like?  (36:53) Synthetic data and "mad cow disease"  (39:22) The future of publishing and media  (41:54) Do we need neurosymbolic AI?  (43:40) Will you cooperate with Anthropic if they get to AGI first?  (47:42) What is your advice to parents who are anxious for their kids' future?  (49:46) If you had infinite resources, what would you pursue?? Learn more about your ad choices. Visit podcastchoices.com/adchoices

Nicholas Thompson sits down with some of the sharpest minds working at the edges of artificial intelligence in The Most Interesting Thing in A.I.. This isn't a dry technical briefing or a series of speculative futures; instead, each conversation digs into the tangible, often surprising ways this technology is already altering the fabric of our daily lives and institutions. You'll hear from leading thinkers who cut through the hype to discuss the real ethical dilemmas, economic shifts, and social transformations unfolding right now. Produced by Atlantic Re:think and PwC, the podcast provides a grounded space to explore questions about creativity, power, work, and truth in an age of intelligent machines. The discussions are built on the premise that understanding AI's impact requires looking beyond code and algorithms to consider human values and consequences. Tune in for thoughtful, accessible dialogues that reframe how we think about one of the most significant forces of our time.
Author: Language: English Episodes: 41

The Most Interesting Thing in AI
Podcast Episodes
The Case Against the AI Bubble - Azeem Azhar with Nicholas Thompson [not-audio_url] [/not-audio_url]

Duration: 1:05:15
Among the many eye-popping numbers of the AI industry—from trillions in investments to billions in spending—one stands out: $0 in profit among leading AI companies. According to Bloomberg, “never before has so much money…
The Race to Superintelligence - Richard Socher with Nicholas Thompson [not-audio_url] [/not-audio_url]

Duration: 1:08:45
As AI’s capabilities improve, reports of “rogue” agents and misaligned systems are becoming more frequent. In response, some activists, academics, and politicians have called for a pause in development, warning of the da…
How to Get Hired in the AI Era - Clara Shih with Nicholas Thompson [not-audio_url] [/not-audio_url]

Duration: 50:43
For years, tech CEOs have promised that AI will take on the menial, repetitive tasks that have long been a part of office life. Typically, those tasks are assigned to younger, less experienced workers—and poll after poll…
Meta's Plan to Win in AI - Andrew Bosworth with Nicholas Thompson [not-audio_url] [/not-audio_url]

Duration: 50:58
However you feel about Meta, Andrew Bosworth has likely played a part in it. The long-serving right hand to Mark Zuckerberg and current Chief Technology Officer, “Boz” has helped shape almost every stage of the company’s…