405: Epilepsy & Seizures - Part 1 - Brain connections, MCAS, Histamines and the GLP1 GLP2 and GIP system!

405: Epilepsy & Seizures - Part 1 - Brain connections, MCAS, Histamines and the GLP1 GLP2 and GIP system!

Author: The Natural Alternative - with Madonna Guy ND July 22, 2026 Duration: 8:19

Epilepsy & Seizures – Part 1: Brain Connections, MCAS, Histamines & the GLP‑1 / GLP‑2 / GIP System**

Epilepsy and seizure activity are not just electrical storms in the brain — they’re deeply connected to **inflammation, mast‑cell activation (MCAS), histamine overload, gut permeability, mitochondrial stress, and disrupted neural signalling**. When mast cells fire too easily, histamine rises, the blood–brain barrier becomes more reactive, and neurons lose their stability. Add poor sleep, stress, nutrient depletion, or environmental triggers, and the brain becomes primed for mis‑firing. The gut–brain axis is central here: when the gut leaks, endotoxins enter circulation, inflammation rises, and neural signalling becomes unstable. This is why many people with seizure patterns also experience sensory overload, anxiety, gut issues, behavioural swings, and histamine symptoms — it’s all part of the same inflammatory loop.

The incretin system — **GLP‑1, GLP‑2 and GIP** — sits right at the centre of this gut–brain connection. **GLP‑1** helps calm inflammation and stabilise metabolic stress, supporting more predictable neural firing. **GLP‑2** repairs gut lining, reduces endotoxin load, and stabilises mast cells, which is crucial when histamine is part of the picture. **GIP** supports metabolic flexibility and energy regulation, helping the brain maintain stable signalling. Many people also explore supportive tools such as **redox signalling support**, **zeolites**, **DHA/EPA**, **phosphatidylserine**, **choline**, **magnesium threonate**, **probiotics**, **homeopathics**, and **Solex AO Bioresonance** for daily frequency balancing, Inner Voice emotional scans, and custom playlists. These approaches don’t “treat” epilepsy — they support the underlying physiology that influences neural stability, inflammation, and signalling.

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# 🌿 **TriGLP Resources, Videos & Ordering Links**

### 🎥 **Hear the Inventors Explain How TriGLP Was Created**  
[https://youtu.be/FRbLhBtWC2U](https://youtu.be/FRbLhBtWC2U)

### 🎥 **Madonna’s 10‑Minute Video: How TriGLP Supports Nutrient Absorption**  
[https://youtu.be/Qyum-XcaydA](https://youtu.be/Qyum-XcaydA)

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# 🛒 **Ordering TriGLP**

### ⭐ **Customer‑Only (Retail)**  
[https://madonnaguy.myorygn.co/shop](https://madonnaguy.myorygn.co/shop)

### ⭐ **Distributor or Retail (Either Option Works)**  
[https://madonnaguy.orygn.co/shop](https://madonnaguy.orygn.co/shop)  
or  
jasonguy.orygn.co

Distributor accounts are **free to join** if people want to share the product and build a business

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# 🌿 **New Leaf Clinic Contact**  
For guidance, education, and support, contact:  
**Madonna – New Leaf Natural Therapies**  
📞 **0417 643 849** (Australia)

#Epilepsy #Seizures #NeuralSignalling #BrainInflammation #MCAS #HistamineIntolerance #GutBrainAxis #GLP1 #GLP2 #GIP #TriGLP #RedoxSignalling #Zeolites #MagnesiumThreonate #DHA #EPA #Phosphatidylserine #Choline #ProbioticsForMood #Homeopathics #SolexAO #InnerVoiceScan #EZScan #Bioresonance #FrequencyHealing #HolisticNeurology #HolisticHealth #NewLeafNaturalTherapies #MadonnaGuy #WholeBodyHealing


Madonna Guy brings a thoughtful and grounded perspective to the often noisy world of wellness in The Natural Alternative. As a practicing naturopath, she sits down with a diverse range of experts-from scientists and researchers to seasoned practitioners in various fields-to explore the practical intersections of traditional wisdom and modern evidence. This isn't about quick fixes or extreme ideologies; instead, each conversation unfolds like a deep dive into how our bodies and minds truly work. You'll hear discussions that thoughtfully examine nutrition, mental well-being, sustainable fitness, and the science behind holistic practices, all aimed at empowering informed choices. The tone is curious and conversational, making complex topics accessible without oversimplifying them. Tune into this podcast for a refreshingly balanced take on health, where the goal is building a resilient and vibrant life through understanding, not dogma. Madonna's approach makes The Natural Alternative a trusted space for anyone looking to move beyond the headlines and cultivate a personal sense of vitality.
Author: Language: English Episodes: 50

The Natural Alternative - with Madonna Guy
Podcast Episodes