The Truth about Magnesium Spray: What is the Scientific Evidence?

The Truth about Magnesium Spray: What is the Scientific Evidence?

Author: Annika Angelo, M.S. January 10, 2025 Duration: 34:32

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Ever wonder if there's any truth to those advertisements about magnesium spray? Well, look no further: I've looked into the research FOR you! Today I break down the research on magnesium spray and tell you the truth about if it works, how to absorb it, and who might benefit from it. Scroll down to find specific topics and jump to that time in the episode.


As always, nutrition does not heal mental health; however, it can support the management of symptoms.


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TIMESTAMPS

(00:00) Intro

(03:27) Magnesium's role in the body

(06:23) Can magnesium be absorbed by the skin?

(10:46) Research studies on magnesium spray

(22:44) Topical magnesium for active labor study

(24:58) Recap

(29:20) How to make your own magnesium spray

REFERENCES

Al Bakir, I., Adaba, F., Patel, K., & Nightingale, J. (2018). Topical magnesium therapy treats hypomagnesaemia in some ileostomy patients. Clinical Nutrition, 37(Supplement 1), S69. ⁠https://doi.org/10.1016/j.clnu.2018.06.1284⁠

Arezoo Heydari, Nourossadat Kariman, Zahra Naeje, & Farzaneh Ahmadi. (2018). Effect of Topical Application of Magnesium Sulfate on the Intensity of Labor Pain: Double Blind Clinical Trial. Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 21(5), 58–65. ⁠https://doi.org/10.22038/ijogi.2018.11385⁠

Athavale, A., Miles, N., Pais, R., Snelling, P., & Chadban, S. J. (2023). Transdermal Magnesium for the Treatment of Peripheral Neuropathy in Chronic Kidney Disease: A Single-Arm, Open-Label Pilot Study. Journal of Palliative Medicine, 26(12), 1654–1661. ⁠https://doi.org/10.1089/jpm.2023.0229⁠

Engen, D. J., McAllister, S. J., Whipple, M. O., Cha, S. S., Dion, L. J., Vincent, A., Bauer, B. A., & Wahner-Roedler, D. L. (2015). Effects of transdermal magnesium chloride on quality of life for patients with fibromyalgia: a feasibility study. Journal of Integrative Medicine, 13(5), 306–313. ⁠https://doi.org/10.1016/S2095-4964(15)60195-9⁠

Jain, V., Urvashi, Khan, J., & Gambhir, S. (2023). A randomized controlled trial of transdermal magnesium oil for chronic low back pain management. Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research), 14(4), 1992–1997.

Kuriyama, A., Maeda, H. & Sun, R. Topical application of magnesium to prevent intubation-related sore throat in adult surgical patients: a systematic review and meta-analysis. Can J Anesth/J Can Anesth 66, 1082–1094 (2019). ⁠https://doi.org/10.1007/s12630-019-01396-7⁠

Lindsy Kass, Andrea Rosanoff, Amy Tanner, Keith Sullivan, William McAuley, & Michael Plesset. (2017). Effect of transdermal magnesium cream on serum and urinary magnesium levels in humans: A pilot study. PLoS ONE, 12(4), e0174817. ⁠https://doi.org/10.1371/journal.pone.0174817⁠

Navin Chandrakanth Chandrasekaran, Sanchez, W. Y., Mohammed, Y. H., Grice, J. E., Roberts, M. S., & Barnard, R. T. (2016). Permeation of topically applied Magnesium ions through human skin is facilitated by hair follicles. Magnesium Research, 29(2), 35–42.

https://doi.org/10.1684/mrh.2016.0402Rahmanian, E., Tanideh, N., Karbalay-doust, S., Mehrabani, D., Rezazadeh, D., Ketabchi, D., EskandariRoozbahani, N., Hamidizadeh, N., Rahmanian, F., & Namazi, M. R. (2024). The effect of topical magnesium on healing of pre-clinical burn wounds. Burns, 50(3), 630–640. ⁠https://doi.org/10.1016/j.burns.2023.10.015⁠



Hosted by nutrition research expert and science communicator Annika Angelo, M.S., The Nutritional Mental Health Podcast explores the fascinating and growing discipline of nutritional psychology. Each episode delves into the tangible connections between what we consume and how we think and feel, moving beyond general wellness trends to focus on evidence-based discussions. Annika brings clarity to complex research, particularly regarding ADHD and cognitive function, translating scientific findings into practical insights. This isn't just about listing superfoods; it's a deep, nuanced conversation on how specific nutrients, dietary patterns, and gut health directly influence mood, focus, and mental resilience. Tuning into this podcast means hearing from a knowledgeable guide who is passionate about making nutritional science accessible and actionable. You'll find episodes that examine the mechanisms behind food-mood interactions, debunk common myths, and offer realistic strategies for harnessing diet to support mental well-being. For those looking to engage further, Annika offers additional resources through her Nutrimind Community and a weekly newsletter, both focused on continuing the conversation around ADHD and nutrition. The overall aim is to provide a reliable, science-backed resource for anyone curious about taking a more informed and intentional approach to their mental health through the lens of nutrition.
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