Episode 148: Control of Gene Expression

Episode 148: Control of Gene Expression

Author: James Fodor September 30, 2024 Duration: 1:09:05
An introduction to the processes by which cells control which genes are expressed. We begin with an overview of why genetic regulation is necessary and the key stages where such regulation occurs, including key concepts such as transcription factors and DNA binding domains. We then discuss prokaryotic gene regulation, focusing on the lac operon in E. coli. We then expand the discussion to cover the various mechanisms of eukaryotic gene regulation, including chromatic remodelling, transcriptional regulation, post-transcriptional regulation, RNA editing, and micro RNAs. Recommended pre-listening is Episodes 34-35: DNA Structure and Function, and Episode 118: Cell Signalling. If you enjoyed the podcast please consider supporting the show by making a PayPal donation or becoming a Patreon supporter. https://www.patreon.com/jamesfodor https://www.paypal.me/ScienceofEverything

Curiosity about how the world works is a universal trait, and The Science of Everything Podcast is built on that very impulse. Host James Fodor guides conversations that roam freely across disciplines, from the physics of black holes to the complexities of human behavior studied in social sciences. Each episode feels like a deep dive into a new subject, where the common thread is a rigorous yet accessible application of the scientific method. You’ll hear explanations that break down complex ideas without oversimplifying them, focusing on the fascinating insights that research reveals about our universe and our place within it. This isn't a lecture series, but rather an exploration driven by genuine inquiry. Whether the topic is rooted in biology, chemistry, sociology, or astronomy, the aim is to connect the dots between abstract principles and the tangible reality we experience. The result is a consistently engaging audio experience that reminds us just how much there is left to discover. Tune in to this thoughtful podcast for a regular dose of understanding, designed to satisfy both the casual question-asker and the dedicated lifelong learner.
Author: Language: English Episodes: 50

The Science of Everything Podcast
Podcast Episodes
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Episode 126: Depression and Serotonin [not-audio_url] [/not-audio_url]

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Episode 125: Earthquakes [not-audio_url] [/not-audio_url]

Duration: 1:07:05
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Episode 124: Volcanoes [not-audio_url] [/not-audio_url]

Duration: 55:29
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Episode 123: Respiratory and Circulatory Systems Part 2 [not-audio_url] [/not-audio_url]

Duration: 1:00:28
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Episode 122: Respiratory and Circulatory Systems Part 1 [not-audio_url] [/not-audio_url]

Duration: 47:54
The first in a two-part episode covering the circulatory and respiratory systems, including a discussion of the anatomy of the heart, the process of contraction, and the generation and propagation of electrical activity.…
Episode 121: The Biology of Pain [not-audio_url] [/not-audio_url]

Duration: 51:06
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Episode 120: Computational Chemistry Part 2 [not-audio_url] [/not-audio_url]

Duration: 1:13:01
Building on the previous discussion of Hartree-Fock Theory, I discuss the inclusion of basis functions to produce the Roothaan equations, and the method of solving these using self-consistent field methods. I then provid…