How to Engineer AI Inference Systems with Philip Kiely - #766

How to Engineer AI Inference Systems with Philip Kiely - #766

Author: Sam Charrington April 30, 2026 Duration: 54:51
In this episode, Philip Kiely, head of AI education at Baseten, joins us to unpack the fast-evolving discipline of inference engineering. We explore why inference has become the stickiest and most critical workload in AI, how it blends GPU programming, applied research, and large-scale distributed systems, and where the line sits between inference and model serving. Philip shares how research-to-production can move in hours, not months, and why understanding “the knobs” of inference—batching, quantization, speculation, and KV cache reuse—lets teams design better products and SLAs. We trace the inference maturity journey from closed APIs to dedicated deployments and in-house platforms, discuss GPU lifecycles, and survey today’s runtime landscape, including vLLM, SGLang, and TensorRT LLM. Finally, we look ahead to agents and multimodality, making the case for specialized, workload-specific runtimes when performance and efficiency matter most. The complete show notes for this episode can be found at https://twimlai.com/go/766.

Hosted by industry analyst and commentator Sam Charrington, The TWIML AI Podcast (formerly This Week in Machine Learning & Artificial Intelligence) serves as a vital conduit between cutting-edge research and its real-world implications. This isn't just a series of technical lectures; it's a series of conversations that unpack how AI and machine learning are actively reshaping industries and societal structures. Each episode connects you directly with leading researchers, engineers, and innovative thinkers who are defining the frontiers of the field. The discussions go beyond abstract theory to explore the practical challenges, ethical considerations, and business transformations driven by these technologies. Whether you're a data scientist deep in the code, a tech-savvy leader strategizing implementation, or simply fascinated by the future of intelligent systems, this podcast provides the context and depth needed to stay informed. By focusing on the people behind the algorithms and the ideas powering the platforms, Sam creates a resource that is both intellectually substantive and genuinely engaging, building a thoughtful community around one of the most significant technological shifts of our time.
Author: Language: English Episodes: 100

The TWIML AI Podcast (formerly This Week in Machine Learning & Artificial Intelligence)
Podcast Episodes
π0: A Foundation Model for Robotics with Sergey Levine - #719 [not-audio_url] [/not-audio_url]

Duration: 52:30
Today, we're joined by Sergey Levine, associate professor at UC Berkeley and co-founder of Physical Intelligence, to discuss π0 (pi-zero), a general-purpose robotic foundation model. We dig into the model architecture, w…